| Cat. No. |
Product Name |
Information |
| PC-45834 |
MK-0812 succinate
CCR2 antagonist
|
MK-0812 succinate is a potent CCR2 specific antagonist that blocks MCP-1 mediated response with an IC50 of 3.2 nM. |
| PC-45833 |
MK-0812
CCR2 antagonist
|
MK-0812 is a potent CCR2 specific antagonist that blocks MCP-1 mediated response with an IC50 of 3.2 nM. |
| PC-45483 |
RS102895
CCR2 antagonist
|
RS-102895 (Abaucin, RS102895) is a potent and specific CCR2 antagonist with binding IC50 of 360 nM, also is a narrow-spectrum activity against A. baumannii. |
| PC-45482 |
RS102895 hydrochloride
CCR2 antagonist
|
RS102895 hydrochloride is a potent and specific CCR2 antagonist with binding IC50 of 360 nM. |
| PC-45824 |
AMD-070 hydrochloride
CXCR4 antagonist
|
AMD-070 (Mavorixafor) hydrochloride is a potent and selective antagonist of CXCR4 with IC50 of 13 nM in a CXCR4 125I-SDF inhibition binding assay. |
| PC-45823 |
AMD-070
CXCR4 antagonist
|
Mavorixafor (AMD-070, AMD-11070) is a potent and selective antagonist of CXCR4 with IC50 of 13 nM in a CXCR4 125I-SDF inhibition binding assay. |
| PC-42391 |
IT1t dihydrochloride
CXCR4 inhibitor
|
IT1t (Isothiourea 1t) dihydrochloride is a highly potent, selective, orally bioavailable CXCR4 inhibitor with binding IC50 of 8 nM for hCXCR4, IC50 of 1.1 nM in Ca2+-mobilization assays. |
| PC-42390 |
IT1t
CXCR4 inhibitor
|
A highly potent, selective, orally bioavailable CXCR4 inhibitor with binding IC50 of 8 nM for hCXCR4, IC50 of 1.1 nM in Ca2+-mobilization assays. |
| PC-23972 |
Reparixin L-lysine salt
CXCR1/2 inhibitor
|
Reparixin L-lysine salt (Repertaxin) is a potent, selective, non-competitive allosteric inhibitor of CXCL8 receptor CXCR1 and CXCR2 activation with IC50 of 1 nM and 100 nM, respectively. |
| PC-23971 |
Reparixin
CXCR1/2 inhibitor
|
Reparixin (Repertaxin) is a potent, selective, non-competitive allosteric inhibitor of CXCL8 receptor CXCR1 and CXCR2 activation with IC50 of 1 nM and 100 nM, respectively. |
| PC-23688 |
RS504393
CCR2 antagonist
|
RS504393 is a potent, selective CCR2 antagonist with IC50 of 89 nM, shows no activity against CCR1. |
| PC-23668 |
CTCE-9908
CXCR4 antagonist
|
CTCE-9908 is a potent and selective CXCR4 antagonist, induces mitotic catastrophe in ovarian cancer cells. |
