| Cat. No. |
Product Name |
Information |
| PC-20531 |
INCB3284 bismesylate
CCR2 antagonist
|
INCB3284 bismesylate (INCB 3284, INCB003284) is a potent, selective and orally bioavailable hCCR2 antagonist with IC50 of 3.7 nM in antagonism of MCP-1 binding to hCCR2 and 4.7 nM in antagonism of chemotaxis activity. |
| PC-20530 |
INCB3284
CCR2 antagonist
|
INCB3284 (INCB 3284, INCB003284) is a potent, selective and orally bioavailable hCCR2 antagonist with IC50 of 3.7 nM in antagonism of MCP-1 binding to hCCR2 and 4.7 nM in antagonism of chemotaxis activity. |
| PC-20525 |
INCB9471
CCR5 antagonist
|
INCB9471 (INCB 9471) is a potent, selective, and orally bioavailable CCR5 antagonist with IC50 of 6.5 nM in MIP-1β assays, exhibits potent anti-HIV-1 activity against ADA and BaL strains with IC50 of 0.36 and 0.16 nM respectively. |
| PC-20372 |
IPG7236
CCR8 inhibitor
|
IPG7236 (IPG 7236) is a potent and selective CCR8 antagonist with chemotaxis IC50 of 33.8 nM. |
| PC-20291 |
NUCC-390 dihydrochloride
CXCR4 agonist
|
NUCC-390 dihydrochloride (NUCC390) is a small molecule agonist of CXCR4, recapitulates the activity of CXCL12α. |
| PC-20290 |
NUCC-390
CXCR4 agonist
|
NUCC-390 (NUCC390) is a small molecule agonist of CXCR4, recapitulates the activity of CXCL12α. |
| PC-49866 |
RIST4721
CXCR2 inhibitor
|
RIST 4721 (Vimnerixin, AZD 4721) is a potent, specific and orally active antagonist of CXCR2, potently inhibits neutrophil chemotaxis with IC50 of 17 nM. |
| PC-49368 |
LN6023
CXCR7 inhibitor
|
LN6023 (LN-6023) a potent, selective and first-in-class inhibitor of the atypical chemokine receptor 3 (ACKR3, CXCR7) with β-arrestin EC50 of 3.5 uM. |
| PC-49265 |
ACT-660602
CXCR3 antagonist
|
ACT-660602 (ACT660602) is a potent, selective and orally bioavailable CXCR3 antagonist with IC50 of 204 nM in human blood. |
| PC-49264 |
ACT-672125
CXCR3 antagonist
|
ACT-672125 (ACT672125) is a potent, selective CXCR3 antagonist with IC50 of 239 nM in human blood. |
| PC-38757 |
CCR9 inhibitor 12
CCR9 inhibitor
|
CCR9 inhibitor 12 is a potent inhibitor of chemokine receptor 9 (CCR9) with IC50 of 20 nM in calcium (Ca2+) FLIPR assay, shows IC50 of 277 nM in chemotaxis assays. |
| PC-38725 |
WZ811
CXCR4 inhibitor
|
WZ811 is a nonpeptidic, small molecule antagonist of CXCR4 with EC50 of 0.3 nM affinity binding assays, suppresses cancer cells aggressive in a variety of cancers. |
