| Cat. No. |
Product Name |
Information |
| PC-42055 |
SCH-563705
CXCR1/CXCR2 inhibitor
|
SCH-563705 is a potent, orally bioavailable dual CXCR2/CXCR1 receptor antagonist with IC50 of 1.3 nM and 7.3 nM, respectively. |
| PC-45199 |
Vicriviroc maleate
CCR5 antagonist
|
Vicriviroc maleate (SCH417690) is a potent, highly selective, and orally bioavailable CCR5 antagonist with Ki of 2.5 nM. |
| PC-42300 |
CXCR2-IN-1
CXCR2 antagonist
|
CXCR2-IN-1 is a potent, CNS penetrant CXCR2 antagonist with pIC50 of 9.3. |
| PC-45834 |
MK-0812 succinate
CCR2 antagonist
|
MK-0812 succinate is a potent CCR2 specific antagonist that blocks MCP-1 mediated response with an IC50 of 3.2 nM. |
| PC-45833 |
MK-0812
CCR2 antagonist
|
MK-0812 is a potent CCR2 specific antagonist that blocks MCP-1 mediated response with an IC50 of 3.2 nM. |
| PC-45483 |
RS102895
CCR2 antagonist
|
RS-102895 (Abaucin, RS102895) is a potent and specific CCR2 antagonist with binding IC50 of 360 nM, also is a narrow-spectrum activity against A. baumannii. |
| PC-45482 |
RS102895 hydrochloride
CCR2 antagonist
|
RS102895 hydrochloride is a potent and specific CCR2 antagonist with binding IC50 of 360 nM. |
| PC-45824 |
AMD-070 hydrochloride
CXCR4 antagonist
|
AMD-070 (Mavorixafor) hydrochloride is a potent and selective antagonist of CXCR4 with IC50 of 13 nM in a CXCR4 125I-SDF inhibition binding assay. |
| PC-45823 |
AMD-070
CXCR4 antagonist
|
Mavorixafor (AMD-070, AMD-11070) is a potent and selective antagonist of CXCR4 with IC50 of 13 nM in a CXCR4 125I-SDF inhibition binding assay. |
| PC-42391 |
IT1t dihydrochloride
CXCR4 inhibitor
|
IT1t (Isothiourea 1t) dihydrochloride is a highly potent, selective, orally bioavailable CXCR4 inhibitor with binding IC50 of 8 nM for hCXCR4, IC50 of 1.1 nM in Ca2+-mobilization assays. |
| PC-42390 |
IT1t
CXCR4 inhibitor
|
A highly potent, selective, orally bioavailable CXCR4 inhibitor with binding IC50 of 8 nM for hCXCR4, IC50 of 1.1 nM in Ca2+-mobilization assays. |
| PC-24281 |
trans-VUF25471
ACKR3 agonist
|
trans-VUF25471 is a small moleculephotoswitchable atypical chemokine receptor 3 (ACKR3) agonist, can be effectively switched from its thermodynamically stable trans state to the less active cis-isomer with a photostationary state of 96%. |
