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Request The Product List ofChemokine Receptor (CCR and CXCR) Chemokine Receptor (CCR and CXCR)

Cat. No. Product Name Information
PC-20372

IPG7236

CCR8 inhibitor

IPG7236 (IPG 7236) is a potent and selective CCR8 antagonist with chemotaxis IC50 of 33.8 nM.
PC-20291

NUCC-390 dihydrochloride

CXCR4 agonist

NUCC-390 dihydrochloride (NUCC390) is a small molecule agonist of CXCR4, recapitulates the activity of CXCL12α.
PC-20290

NUCC-390

CXCR4 agonist

NUCC-390 (NUCC390) is a small molecule agonist of CXCR4, recapitulates the activity of CXCL12α.
PC-49866

RIST4721

CXCR2 inhibitor

RIST 4721 (Vimnerixin, AZD 4721) is a potent, specific and orally active antagonist of CXCR2, potently inhibits neutrophil chemotaxis with IC50 of 17 nM.
PC-49368

LN6023

CXCR7 inhibitor

LN6023 (LN-6023) a potent, selective and first-in-class inhibitor of the atypical chemokine receptor 3 (ACKR3, CXCR7) with β-arrestin EC50 of 3.5 uM.
PC-49265

ACT-660602

CXCR3 antagonist

ACT-660602 (ACT660602) is a potent, selective and orally bioavailable CXCR3 antagonist with IC50 of 204 nM in human blood.
PC-49264

ACT-672125

CXCR3 antagonist

ACT-672125 (ACT672125) is a potent, selective CXCR3 antagonist with IC50 of 239 nM in human blood.
PC-38757

CCR9 inhibitor 12

CCR9 inhibitor

CCR9 inhibitor 12 is a potent inhibitor of chemokine receptor 9 (CCR9) with IC50 of 20 nM in calcium (Ca2+) FLIPR assay, shows IC50 of 277 nM in chemotaxis assays.
PC-38725

WZ811

CXCR4 inhibitor

WZ811 is a nonpeptidic, small molecule antagonist of CXCR4 with EC50 of 0.3 nM affinity binding assays, suppresses cancer cells aggressive in a variety of cancers.
PC-38724

MSX-122

CXCR4 modulator

MSX-122 is a small molecule and partial CXCR4 antagonist, directly binds to the CXCL12 site on CXCR4 and inhibits CXCR4/CXCL12 actions with IC50 of 10 nM.
PC-38704

DF2755A

CXCR1/2 inhibitor

DF2755A is a selective, allosteric, orally acting inhibitor of CXCR1/2 (Kd=2.24/0.94 nM), inhibits human PMN (hPMN) migration induced by CXCL8 and CXCL1 with IC50 of 4.2 and 2.1 nM, respectively.
PC-38669

CXCR7 agonist 1

CXCR7 agonist

CXCR agonist 1 is a potent, selective, small molecule agonist of CXCR7 (ACKR3), induces β-arrestin recruitment to CXCR7 and Akt activation, inhibits CXCL12-induced tube formation in HUVECs with EC50 of 0.96 nM.

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