| Cat. No. |
Product Name |
Information |
| PC-23096 |
CXCR3 antagonist 7D
DENV2 inhibitor
|
CXCR3 antagonist 7D is a specific small molecule CXCR3 antagonist, inhibits CXCL4-mediated DENV2 replication with EC50 of 2.1 uM in monocytic U937-DC-SIGN cells. |
| PC-21815 |
PS372424 hydrochloride
CXCR3 agonist
|
PS372424 hydrochloride is a potent, selective peptidomimetic agonist of human CXC chemokine receptor 3 (CXCR3) with EC50 of 1.1 uM in calcium flux assays, binding affinity of 42 nM. |
| PC-21814 |
PS372424
CXCR3 agonist
|
PS372424 is a potent, selective peptidomimetic agonist of human CXC chemokine receptor 3 (CXCR3) with EC50 of 1.1 uM in calcium flux assays, binding affinity of 42 nM. |
| PC-21470 |
alpha-NETA
CMKLR1 inhibitor
|
alpha-NETA (α-NETA) is a small molecule antagonist of chemerin receptor chemokine-like receptor 1 (CMKLR1), inhibits chemerin-stimulated β-arrestin2 association with CMKLR1 with IC50 of 4.9 uM. |
| PC-21255 |
ZK756326
CCR8 agonist
|
ZK 756326 is a potent, selective nonpeptide agonist of the CC chemokine receptor CCR8, inhibits the binding of the CCR8 ligand I-309 (CCL1) with IC50 of 1.8 uM. |
| PC-21011 |
KAND567
CX3CR1 inhibitor
|
Rugocrixan (KAND567, AZD8797) is a potent, selective and orally available C-X3-C motif chemokine receptor 1 (CX3CR1, fractalkine receptor) antagonist with binding Ki of 3.9 nM (human CX3CR1), 720-fold selectivity over CXCR2. |
| PC-20971 |
CCR7 inhibitor 30c
CCR7 inhibitor
|
CCR7 inhibitor 30c is a potent, selective CC chemokine receptor 7 (CCR7) antagonist with IC50 of 0.43 uM, 25-fold selectivity over CXCR2. |
| PC-20802 |
SCH-479833
CXCR1/2 inhibitor
|
SCH-479833 is a potent, specific and orally active CXCR1 and CXCR2 antagonist with Ki of 0.17 and 7 nM, respectively. |
| PC-20761 |
PF-07054894
CCR6 inhibitor
|
PF-07054894 is a potent, functionally selective CCR6 antagonist, blocks in vitro CCL20- dependent human T cell chemotaxis with IC50 of 5.7 nM. |
| PC-20733 |
AMG487
CXCR3 antagonist
|
AMG487 (AMG 487, VUF10085) is a potent and selective orally bioavailable chemokine (C-X-C motif) receptor 3 (CXCR3) antagonist with IC50 of 8 nM for inhibiting 125I-IP-10 binding. |
| PC-20372 |
IPG7236
CCR8 inhibitor
|
IPG7236 (IPG 7236) is a potent and selective CCR8 antagonist with chemotaxis IC50 of 33.8 nM. |
| PC-20291 |
NUCC-390 dihydrochloride
CXCR4 agonist
|
NUCC-390 dihydrochloride (NUCC390) is a small molecule agonist of CXCR4, recapitulates the activity of CXCL12α. |
