| Cat. No. |
Product Name |
Information |
| PC-47505 |
Motixafortide
CXCR4 antagonist
|
Motixafortide (BL-8040, BKT-140, TF-14016) is a 14-residue biostable synthetic peptide, high-affinity CXCR4 antagonist (IC50=1 nM). |
| PC-45771 |
TAK-220
CCR5 antagonist
|
TAK-220 (TAK220) is a potent, specific, orally bioavailable CCR5 antagonist that blocks the binding of MIP-1α to CCR5 with IC50 of 1.4 nM. |
| PC-42443 |
SCH-527123
CXCR2 antagonist
|
SCH-527123 (Navarixin, MK-7123) is a potent, selective, orally bioavailable CXCR2/CXCR1 receptor antagonist with Kd of 0.08 and 41 nM for cynomolgus CXCR2 and CXCR1, respectively. |
| PC-42417 |
CCX140
CCR2 antagonist
|
CCX140 (Ilacirnon, CCX140B) is a potent, selective, orally bioavailable CCR2 antagonist with Kd of 2.3 nM for hCCR2. |
| PC-45057 |
SB-225002
CXCR2 antagonist
|
SB-225002 (SB225002) is a potent, selective, non-peptide CXCR2 antagonist with IC50 of 22 nM. |
| PC-45905 |
Plerixafor octahydrochloride
CXCR4 inhibitor
|
Plerixafor octahydrochloride (JM-3100, AMD3100, SID-791) is a potent, selective CXCR4 inhibitor (IC50=44 nM) that inhibits the replication of various HIV-1 and HIV-2 strains in various cell lines with EC50 of 10 ng/ml. |
| PC-42164 |
AMD3100
CXCR4 inhibitor
|
Plerixafor (AMD3100) is a potent, selective CXCR4 inhibitor (IC50=44 nM) that inhibits the replication of various HIV-1 and HIV-2 strains in various cell lines with EC50 of 10ng/ml. |
| PC-45838 |
INCB3344
CCR2 antagonist
|
INCB3344 (INCB 3344) is a potent, selective and orally bioavailable CCR2 antagonist with IC50 of 5.1 nM and 9.5 nM for hCCR2 and mCCR2, respectively, in MCP-1 binding assays. |
| PC-42073 |
SCH-546738
CXCR3 inhibitor
|
SCH-546738 (SCH546738) is a potent, selective and non-competitive CXCR3 antagonist with binding Ki of 0.4 nM for human CXCR3. |
| PC-42055 |
SCH-563705
CXCR1/CXCR2 inhibitor
|
SCH-563705 is a potent, orally bioavailable dual CXCR2/CXCR1 receptor antagonist with IC50 of 1.3 nM and 7.3 nM, respectively. |
| PC-45199 |
Vicriviroc maleate
CCR5 antagonist
|
Vicriviroc maleate (SCH417690) is a potent, highly selective, and orally bioavailable CCR5 antagonist with Ki of 2.5 nM. |
| PC-42300 |
CXCR2-IN-1
CXCR2 antagonist
|
CXCR2-IN-1 is a potent, CNS penetrant CXCR2 antagonist with pIC50 of 9.3. |
