Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-Metabolic Enzyme/Protease-Protein Phosphatase/PTP

Request The Product List ofProtein Phosphatase/PTP Protein Phosphatase/PTP

Cat. No. Product Name Information
PC-38186

IACS-15414

SHP2 inhibitor

IACS-15414 (IACS 15414) is a potent, selective, orally bioavailable SHP2 inhibitor with IC50 of 122 nM.
PC-38184

SBI-4668

SHP2 inhibitor

SBI-4668 (SBI-668) is a novel furanylbenzamide molecule inhibitor of both WT and oncogenic SHP2 with IC50 of 0.73/1.8 uM for Wt SHP2/SHP2-E76K, 13-fold selective over PTP1B and 73-fold selective over STEP.
PC-38183

SBI-2130

SHP2 inhibitor

SBI-2130 (SBI 2130) is a novel furanylbenzamide molecule inhibitor of both WT and oncogenic SHP2 with IC50 of 0.22/5.0 uM for Wt SHP2/SHP2-E76K.
PC-38181

RMC-4630

SHP2 inhibitor

RMC-4630 (Vociprotafib) is a potent and selective inhibitor of SHP2, a central node in the RAS signaling pathway.
PC-38180

TNO155

SHP2 inhibitor

Batoprotafib (TNO155) is a highly potent, selective, orally active, and allosteric SHP2 (PTPN11) inhibitor with IC50 of 11 nM.
PC-38070

IACS-13909

SHP2 inhibitor

IACS-13909 (IACS13909) is a potent, and selective allosteric inhibitor of SHP2 with IC50 of 15.7 nM (hSHP2 full length), Kd of 32 nM (ITC).
PC-36051

SHP2 inhibitor 14

SHP2 inhibitor 14 is a novel potent, selective, allosteric, orally acitve SHP2 inhibitor with IC50 of 28 nM.
PC-36050

SHP389

SHP2 inhibitor

SHP389 (SHP-389, SHP 389) is a novel potent, selective, allosteric SHP2 inhibitor with IC50 of 36 nM, shows with impressive hERG selectivity (IC50>30 uM).
PC-36040

SHP2 inhibitor 9

SHP2 inhibitor

SHP2 inhibitor 9 is a potent, selective inhibitor of SHP2 with IC50 of 48 nM, inhibits p-ERK in KYSE520 cells with IC50 of 28 nM.
PC-36039

SHP2 inhibitor 8

SHP2 inhibitor

SHP2 inhibitor 8 is a potent, selective inhibitor of SHP2 with IC50 of 5 nM, inhibits p-ERK in KYSE520 cells with IC50 of 5 nM.
PC-36038

SHP394

SHP2 inhibitor

SHP394 (SHP-394, SHP 394) is a potent, selective, orally bioavailable inhibitor of SHP2 with IC50 of 23 nM, shows p-ERK inhibition with IC50 of 18 nM in cellular assays.
PC-35819

SHP2 inhibitor LY6

SHP2 inhibitor

SHP2 inhibitor LY6 (LY6) is a small molecule inhibitor that stabilizes the autoinhibited conformation of the oncogenic tyrosine phosphatase SHP2, inhibits SHP2 with IC50 of 9.8 uM, 7-fold selectivity over SHP1.

Request The Product List

* Indicates a Required FieldYour information is safe with us.

  • *Product List:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Country:
  • Additional Information:

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com