| Cat. No. |
Product Name |
Information |
| PC-60897 |
ML400
LMPTP inhibitor
|
ML400 is a potent, selective, allosteric LMPTP inhibitor with IC50 of 1.68 uM, displays good selective against other phosphatases. |
| PC-60896 |
LMPTP inhibitor 23
LMPTP inhibitor
|
LMPTP inhibitor 23 is a potent, selective, orally bioavailable low-molecular-weight protein tyrosine phosphatase (LMPTP) inhibitor with IC50 of 0.8 uM. |
| PC-60895 |
MLS-0322825
LMPTP inhibitor
|
MLS-0322825 is a novel potent low-molecular-weight protein tyrosine phosphatase (LMPTP) inhibitor with IC50 of 3.3 uM. |
| PC-60691 |
BCI-215
DUSP-MKP inhibitor
|
BCI-215 (BCI215) is a potent, tumor cell-selective dual specificity MAPK phosphatase (DUSP-MKP) inhibitor. |
| PC-60664 |
NSC117079
PHLPP inhibitor
|
NSC117079 is a selective protein phosphatase PHLPP inhibitor with IC50 of 4 uM for PP2C domain of PHLPP2. |
| PC-60663 |
NSC45586
PHLPP inhibitor
|
NSC45586 is a selective protein phosphatase PHLPP inhibitor with IC50 of 4 uM for PP2C domain of PHLPP2. |
| PC-50005 |
AQX 1125 acetate
SHIP1 activator
|
AQX 1125 acetate (Rosiptor) is a sepecific, orally bioavailable SHIP1 activator with no effect on functional androgen, oestrogen, oestrogen-related receptor α, glucocorticoid, mineralocorticoid and progesterone receptor at 30 uM. |
| PC-50004 |
AQX 1125
SHIP1 activator
|
AQX 1125 (Rosiptor) is a specific, orally bioavailable SHIP1 activator with no effect on functional androgen, oestrogen, oestrogen-related receptor α, glucocorticoid, mineralocorticoid and progesterone receptor at 30 uM. |
| PC-60421 |
SCB-4380
PTPRZ inhibitor
|
SCB-4380 (SCB 4380, SCB4380) is the first potent, selective inhibitor for PTPRZ (protein tyrosine phosphatase receptor-type Z) with IC50 of 0.4 uM against human Z-ICR-catalyzed hydrolysis. |
| PC-70159 |
NCI-83633
PP2C inhibitor
|
NCI-83633 (Leucine-2-napthylamide) is a small molecule inhibitor of PP2C that activates extensive 3' cleavage at a concentration 50-fold below that required by fluoride or CP. |
| PC-70158 |
DT-061
PP2A activator
|
SMAP (DT-061, NZ-8-061) is an orally bioavailable small molecule activator of PP2A, inhibits KRAS-driven tumor growth. |
| PC-70157 |
CS-11
PP2A-β-catenin inhibitor
|
CS-11 is a novel small molecule inhibitor that inhibits PP2A and β-catenin interaction by selectively engaging PR55α binding site (Kd=45 pM). |
