| Cat. No. |
Product Name |
Information |
| PC-70159 |
NCI-83633
PP2C inhibitor
|
NCI-83633 (Leucine-2-napthylamide) is a small molecule inhibitor of PP2C that activates extensive 3' cleavage at a concentration 50-fold below that required by fluoride or CP. |
| PC-70158 |
DT-061
PP2A activator
|
SMAP (DT-061, NZ-8-061) is an orally bioavailable small molecule activator of PP2A, inhibits KRAS-driven tumor growth. |
| PC-70157 |
CS-11
PP2A-β-catenin inhibitor
|
CS-11 is a novel small molecule inhibitor that inhibits PP2A and β-catenin interaction by selectively engaging PR55α binding site (Kd=45 pM). |
| PC-70156 |
MP07-66
PP2A activator
|
MP07-66 is a novel FTY720 analog that acts as PP2A activator, disrupts the SET/PP2A interaction devoid of immunosuppressive effects leads to the reactivation of PP2A. |
| PC-70155 |
LB102
PP2A inhibitor
|
LB102 (LB-1.2, LB 102) is a potent, selective serine/threonine protein phosphatase 2A (PP2A) inhibitor with IC50 of 0.4 uM. |
| PC-70136 |
AS1949490
SHIP2 inhibitor
|
AS-1949490 (AS1949490) is a potent, selective SHIP2 inhibitor with IC50 of 0.34/0.62 uM for mouse/human SHIP2. |
| PC-60249 |
BN82002
CDC25 phosphatase inhibitor
|
BN82002 is a potent Cdc25 dual specificity phosphatase inhibitor with IC50 of 2-6 uM for Cdc25A/B/C. |
| PC-60248 |
NSC95397
Cdc25 inhibitor
|
NSC95397 is a potent, selective, reversible Cdc25 dual specificity phosphatase inhibitor with Ki of 32/96/40 nM for Cdc25A/B/C, respectively. |
| PC-60183 |
DUSP6 inhibitor BCI
DUSP6 inhibitor
|
BCI (NSC150117) is a small-molecule, allosteric inhibitor of DUSP6 (dual-specificity phosphatase 6) with IC50 of 12.3 uM. |
| PC-60081 |
Razuprotafib sodium
VE-PTP inhibitor
|
AKB-9778 (Razuprotafib) sodium is a potent, selective inhibitor of vascular endothelial protein tyrosine phosphatase (VE-PTP, HPTPβ) with IC50 of 17 pM. |
| PC-45587 |
Calyculin A
Phosphatase inhibitor
|
Calyculin A is a more potent phosphatase inhibitor than Okadaic acid, inhibits catalytic subunit of type-2A phosphatase (IC50 =0.5-1 nM), calyculin A is more effective for protein phosphatase type-1. |
| PC-42921 |
MSI-1436
PTP1B inhibitor
|
MSI-1436 (Trodusquemine) is an non-competitive, allosteric inhibitor of PTP1B with Ki of 0.6 uM for PTP1B 1-405. |
