Cat. No. |
Product Name |
Information |
PC-20596 |
PTP1B-IN-2
PTP1B inhibitor
|
PTP1B-IN-2 (compound P6) is a potent, selective potent protein tyrosine phosphatase 1B (PTP1B) inhibitor with IC50 of 50 nM, >40-fold selectivity over SHP-2 and LAR, >15-fold selectivity over the highly homologous TCPTP. |
PC-20548 |
AQX-MN100
SHIP1 agonist
|
AQX-MN100 (ZPR-MN100) is a small-molecule agonist of SHIP1, enhances SHIP1 enzyme activity in vitro. |
PC-20470 |
PTP1B inhibitor BDB
PTP1B inhibitor
|
PTP1B inhibitor BDB is a natural compound found in marine red algaea, is a selective, cell‐permeable and competitive inhibitor of PTP1B with IC50 of 1.86 uM. |
PC-20469 |
PTP1B inhibitor BBR
PTP1B inhibitor
|
PTP1B inhibitor BBR is a selective, non-competitive allosteric inhibitor of the protein tyrosine phosphatase PTP1B with IC50 of 8 uM. |
PC-20339 |
PTPN2 inhibitor 9
PTPN2 inhibitor
|
PTPN2 inhibitor 9 (PTP9) is small molecule inhibitor of protein tyrosine phosphatase non-receptor type 2 (PTPN2), sensitizes tumor cells to IFNγ treatment in vitro and to anti-PD-1 therapy in vivo. |
PC-72526 |
SCP1 inhibitor T-62
SCP1/REST inhibitor
|
SCP1 inhibitor T-62 (T-62) is a specific, small molecule covalent inhibitor of small CTD phosphatase 1 (SCP1), reduces transcription factor REST protein level HEK293 cells. |
PC-72524 |
SCP1 inhibitor T-65
SCP1/REST inhibitor
|
SCP1 inhibitor T-65 (T-65) is a specific, small molecule covalent inhibitor of small CTD phosphatase 1 (SCP1), reduces transcription factor REST protein level HEK293 cells with EC50 of 1.5 uM. |