| Cat. No. |
Product Name |
Information |
| PC-22856 |
Thienopyridone
PRL/PTP4A inhibitor
|
Thienopyridone is a potent and selective phosphatase of regenerating liver (PRL) phosphatases inhibitor with IC50s of 173 nM, 277 nM and 128 nM for PRL-1 (PTP4A1), PRL-2 (PTP4A2), and PRL-3 (PTP4A3), respectively. |
| PC-22839 |
Cyclosporin A
PP2B inhibitor
|
Cyclosporin A (CsA, Cyclosporine A) is a immunosuppressant agent and highly specific inhibitor of the Ca2+/calmodulin-dependent protein phosphatase PP2B with IC50 of 65 nM in rat pancreatic acinar cells. |
| PC-22546 |
SMIP-031
PPM1A inhibitor
|
SMIP-031 is a potent small molecule inhibitor of metal-dependent phosphatase PPM1A with IC50 of 180 nM, efficiently activates autophagy and reduces the mycobacterium tuberculosis (Mtb) infection. |
| PC-22375 |
CDC14 phosphatase inhibitor 15
CDC14 inhibitor
|
CDC14 phosphatase inhibitor 15 is a first-in-class, potent, selective, and bioavailable inhibitor of CDC14 phosphatase with IC50 of 93 nM and 220 nM for human CDC14A and CDC14B, respectively, >50-fold selective over other PTPs. |
| PC-22168 |
SCP1 inhibitor GR-28
SCP1/REST inhibitor
|
SCP1 inhibitor GR-28 is a covalent small molecule inhibitor of small C-terminal domain phosphatase 1 (SCP1) with kinact/KI 1383 min-1 M-1, causes degrades REST protein in REST-dependent glioblastoma cells. |
| PC-21980 |
SBI-0802767
LMPTP inhibitor
|
SBI-0802767 is a potent, selective low molecular weight protein tyrosine phosphatase (LMPTP) inhibitor with IC50 of 239 nM, remarkably selective over class I tyrosine-specific and dual-specific PTPs. |
| PC-21979 |
LMPTP inhibitor 6g
LMPTP inhibitor
|
LMPTP inhibitor 6g is a potent, selective, uncompetitive low molecular weight protein tyrosine phosphatase (LMPTP) inhibitor with IC50 of 83 nM, >1000-fold selective over other phosphatases. |
| PC-21978 |
LMPTP inhibitor 5d
LMPTP inhibitor
|
LMPTP inhibitor 5d is a potent, selective low molecular weight protein tyrosine phosphatase (LMPTP) inhibitor with IC50 of 20 nM, >1000-fold selective over other phosphatases. |
| PC-21977 |
LMPTP inhibitor 23 dihydrochloride
LMPTP inhibitor
|
LMPTP inhibitor 23 dihydrochloride is a potent, selective, orally bioavailable low-molecular-weight protein tyrosine phosphatase (LMPTP) inhibitor with IC50 of 0.8 uM. |
| PC-21976 |
Raphin1 acetate
PPP1R15B inhibitor
|
Raphin1 acetate (PPP1R15B inhibitor Raphin1) is a potent, selective, BBB-penetrant, orally bioavailable inhibitor of regulatory subunit of protein phosphatase 1, PPP1R15B, binds to the R15B-PP1c holophosphatase with Kd of 33 nM, 30-fold selective in binding R15B-PP1c over R15A-PP1c and does not bind to PP1c. |
| PC-21911 |
G6P6373
CLas STP inhibitor
|
G6P6373 is a specific Candidatus Liberibacter spp dual-specificity phosphatase (CLas STP) with binding KD of 24 uM, confers plant tolerance to Candidatus Liberibacter spp. |
| PC-21910 |
G6P3510
CLas STP inhibitor
|
G6P3510 is a specific Candidatus Liberibacter spp dual-specificity phosphatase (CLas STP) with binding KD of 81.4 uM, confers plant tolerance to Candidatus Liberibacter spp. |
