Cat. No. |
Product Name |
Information |
PC-61271 |
Fumosorinone
SHP2 inhibitor
|
Fumosorinone is a novel potent, selective protein tyrosine phosphatase SHP2 inhibitor with IC50 of 6.31 uM. |
PC-61176 |
NSC 87877
SHP1/2 inhibitor
|
NSC 87877 is potent, selective protein tyrosine phosphatase SHP1 and SHP2 with IC50 of 318 and 355 nM, respectively, also inhibits dual-specificity phosphatase 26 (DUSP26). |
PC-61175 |
RR601
DUSP5 inhibitor
|
RR601 is a potent, selective protein tyrosine phosphatase DUSP5, PTP1B and SHP-2 inhibitor with IC50 of 36 uM, 2.1 uM and 1.1 uM respectively, 8-fold selectivity for PTP1B versus DUSP5. |
PC-60897 |
ML400
LMPTP inhibitor
|
ML400 is a potent, selective, allosteric LMPTP inhibitor with IC50 of 1.68 uM, displays good selective against other phosphatases. |
PC-60896 |
LMPTP inhibitor 23
LMPTP inhibitor
|
LMPTP inhibitor 23 is a potent, selective, orally bioavailable low-molecular-weight protein tyrosine phosphatase (LMPTP) inhibitor with IC50 of 0.8 uM. |
PC-60895 |
MLS-0322825
LMPTP inhibitor
|
MLS-0322825 is a novel potent low-molecular-weight protein tyrosine phosphatase (LMPTP) inhibitor with IC50 of 3.3 uM. |
PC-60691 |
BCI-215
DUSP-MKP inhibitor
|
BCI-215 (BCI215) is a potent, tumor cell-selective dual specificity MAPK phosphatase (DUSP-MKP) inhibitor. |
PC-60664 |
NSC117079
PHLPP inhibitor
|
NSC117079 is a selective protein phosphatase PHLPP inhibitor with IC50 of 4 uM for PP2C domain of PHLPP2. |
PC-60663 |
NSC45586
PHLPP inhibitor
|
NSC45586 is a selective protein phosphatase PHLPP inhibitor with IC50 of 4 uM for PP2C domain of PHLPP2. |
PC-50005 |
AQX 1125 acetate
SHIP1 activator
|
AQX 1125 acetate (Rosiptor) is a sepecific, orally bioavailable SHIP1 activator with no effect on functional androgen, oestrogen, oestrogen-related receptor α, glucocorticoid, mineralocorticoid and progesterone receptor at 30 uM. |
PC-50004 |
AQX 1125
SHIP1 activator
|
AQX 1125 (Rosiptor) is a specific, orally bioavailable SHIP1 activator with no effect on functional androgen, oestrogen, oestrogen-related receptor α, glucocorticoid, mineralocorticoid and progesterone receptor at 30 uM. |
PC-60421 |
SCB-4380
PTPRZ inhibitor
|
SCB-4380 (SCB 4380, SCB4380) is the first potent, selective inhibitor for PTPRZ (protein tyrosine phosphatase receptor-type Z) with IC50 of 0.4 uM against human Z-ICR-catalyzed hydrolysis. |