| Cat. No. |
Product Name |
Information |
| PC-45526 |
CPDA
SHIP2 inhibitor
|
CPDA is a potent SHIP2 inhibitor that enhances in vitro insulin signaling through the Akt pathway more efficiently than AS1949490, and ameliorates abnormal glucose metabolism in diabetic (db/db) mice. |
| PC-45470 |
LB-100
PP2A inhibitor
|
LB-100 (LB100) is a potent serine/threonine protein phosphatase 2A (PP2A) inhibitor. |
| PC-42304 |
NQ301
CD45 inhibitor
|
NQ301 (CD45 inhibitor 211, Compound 211) is a potent antithrombotic agent that inhibits thromboxane A2 receptor and synthase activity, also is a potent, selective inhibitor of CD45 tyrosine phosphatase with IC50 of 200 nM. |
| PC-42166 |
TPI-1
SHP1 inhibitor
|
TPI-1 is a potent and selective, orally-active protein tyrosine phosphatases SHP-1 inhibitor with IC50 of 40 nM (0.01 ug/ml). |
| PC-42207 |
Stibogluconate sodium
PTPs inhibitor
|
Stibogluconate sodium (Sodium stibogluconate) is a multiple antimony compound that has leishmanicidal and potential antineoplastic activities, inhibits protein tyrosine phosphorylase SHP-1 (99% inhibtion at 10 ug/mL), SHP-2 and PTP1B, shows anticancer activity in synergy with IFNs. |
| PC-45510 |
LTV-1
PTPN22 inhibitor
|
LTV-1 is a highly potent, cell-permeable and reversible LYP (lymphoid tyrosine phosphatase, PTPN22) inhibitor with IC50 of 508 nM. |
| PC-42696 |
PTP1B-IN-1
PTP1B inhibitor
|
PTP1B-IN-1 is a 1,2,5-thiadiazolidin-3-one-1,1-dioxide scaffold for design of protein tyrosine phosphatase-1B (PTP1B) inhibitor, shows weak inhibition for PTP1B with IC50 of 1.6 mM. |
| PC-24886 |
Z218484536
PSPH inhibitor
|
Z218484536 is a potent and specific phosphoserine phosphatase (PSPH) inhibitor, inhibits the release of L-serine from cultured astrocytes with IC50 of 0.4 uM, reduces cellular L-serine levels with IC50 of 0.38 uM. |
| PC-24875 |
JUN-1111
Cdc25 inhibitor
|
JUN-1111 is an irreversible and selective Cdc25 phosphatase inhibitor with IC50 values of 0.38, 1.8, 0.66, 28, 37 µM for Cdc25A, Cdc25B, Cdc25C, VHR, PTP1B, respectively. |
| PC-24851 |
OncoACP3
ACP3 ligand
|
OncoACP3 is a specific small ligand of prostatic acid phosphatase (ACP3, ACPP, PAP, PAcP), shows high selectivity over placental alkaline phosphatase, TNAP and human and murine serum albumins. |
| PC-24364 |
Laforin inhibitor 9c
Laforin inhibitor
|
Laforin inhibitor 9c is a highly potent, selective inhibitor of glycogen phosphatase laforin with IC50 of 4.0 nM and Ki value of 1.9 nM, >8000-fold selective over other 15 PTPs. |
| PC-23908 |
PTPN22 inhibitor IC-11
PTPN22 inhibitor
|
I-C11 is a selective, reversible inhibitor of protein tyrosine phosphatase non-receptor type 22 (PTPN22, LYP) with IC50 of 4.6 uM. |
