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Cat. No. Product Name Information
PC-70136

AS1949490

SHIP2 inhibitor

AS1949490 (AS-1949490) is a potent, selective SHIP2 inhibitor with IC50 of 0.34/0.62 uM for mouse/human SHIP2.
PC-60249

BN82002

CDC25 phosphatase inhibitor

BN82002 is a potent Cdc25 dual specificity phosphatase inhibitor with IC50 of 2-6 uM for Cdc25A/B/C.
PC-60248

NSC 95397

Cdc25 inhibitor

NSC 95397 is a potent, selective, reversible Cdc25 dual specificity phosphatase inhibitor with Ki of 32/96/40 nM for Cdc25A/B/C, respectively.
PC-60183

DUSP6 inhibitor BCI

DUSP6 inhibitor

BCI (NSC150117) is a small-molecule, allosteric inhibitor of DUSP6 (dual-specificity phosphatase 6) with IC50 of 12.3 uM.
PC-60081

Razuprotafib sodium

VE-PTP inhibitor

Razuprotafib sodium (AKB-9778) is a potent, selective inhibitor of vascular endothelial protein tyrosine phosphatase (VE-PTP, HPTPβ) with IC50 of 17 pM.
PC-45587

Calyculin A

Phosphatase inhibitor

Calyculin A is a more potent phosphatase inhibitor than Okadaic acid, inhibits catalytic subunit of type-2A phosphatase (IC50 =0.5-1 nM), calyculin A is more effective for protein phosphatase type-1.
PC-42921

MSI-1436

PTP1B inhibitor

MSI-1436 (Trodusquemine) is an non-competitive, allosteric inhibitor of PTP1B with Ki of 0.6 uM for PTP1B 1-405.
PC-42129

SHP099 hydrochloride

SHP2 inhibitor

SHP099 hydrochloride is a potent, selective, allosteric and orally bioavailable protein tyrosine phosphatase SHP2 inhibitor with IC50 of 71 nM.
PC-42128

SHP099

SHP2 inhibitor

SHP099 (SHP-099) is a potent, selective, allosteric and orally bioavailable protein tyrosine phosphatase SHP2 inhibitor with IC50 of 71 nM.
PC-47481

Microcystin-LR

PP2A inhibitor

Microcystin-LR (MC-LR) is a potent, selective inhibitor of protein phosphatase 2A (PP2A) with IC50 of 0.04 nM.
PC-45526

CPDA

SHIP2 inhibitor

CPDA is a potent SHIP2 inhibitor that enhances in vitro insulin signaling through the Akt pathway more efficiently than AS1949490, and ameliorates abnormal glucose metabolism in diabetic (db/db) mice.
PC-45470

LB-100

PP2A inhibitor

LB-100 (LB100) is a potent serine/threonine protein phosphatase 2A (PP2A) inhibitor.

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