| Cat. No. |
Product Name |
Information |
| PC-35963 |
BMS-952048
|
BMS-952048 is a positive allosteric modulator of mGluR5 with EC50 of 10 nM.. |
| PC-43392 |
MTEP hydrochloride
|
MTEP hydrochloride is a potent, selective, non-competitive mGlu5 antagonist with IC50 of 5 nM and Ki of 16 nM. |
| PC-43360 |
ADX-47273
|
ADX-47273 is a potent and selective mGlu5 positive allosteric modulators (PAM) with with EC50 of 170 nM. |
| PC-63236 |
LY2794193
|
LY2794193 is a highly potent and selective mGlu3 receptor agonist with Ki of 0.93 nM and EC50 of 47 nM, >100-fold selectivity over mGlu2 receptor.. |
| PC-43079 |
Methoxy-PEPy
|
Methoxy-PEPy is a potent, selective mGlu5 receptor antagonist with IC50 of 1 nM. |
| PC-63181 |
AZD8529 mesylate
|
AZD8529 is a novel potent, selective mGluR2 positive allosteric modulator with EC50 of 195 nM, does not produce any positive allosteric modulator responses for mGluR1 and 3-8 subtypes. |
| PC-62985 |
L-AP4
|
L-AP4 is a selective group III metabotropic glutamate receptor agonist.. |
| PC-62982 |
LSP1-2111
|
LSP1-2111 is a potent, selective, and brain penetrant group III mGluRs agonist with EC50 of 2.2 and 1.7 uM for mGluR4 and mGluR6, respectively. |
| PC-62958 |
JNJ16567083
|
JNJ16567083 (EMQMCM) is a potent and selective mGluR1 antagonist that shows neuroprotective effects in some hypoxia-ischemia models. |
| PC-62956 |
VU0410425
|
VU0410425 is a potent, selective negative allosteric modulator of rat mGluR1 with IC50 of 140 nM, inactive at human mGluR1 (IC50>30 uM).. |
| PC-62955 |
CDPPB
|
CDPPB is a potent, selective, brain penetrant positive allosteric modulator of mGlu5 receptor with EC50 of 10 nM and 20 nM for human and rat mGluR5, respectively. |
| PC-62593 |
LY 2979165
|
LY2979165 (MP-101) is the alanine prodrug of LY2812223, a selective orthosteric mGlu2 receptor agonist. |
