| Cat. No. |
Product Name |
Information |
| PC-43360 |
ADX-47273
mGlu5 PAM
|
ADX-47273 is a potent and selective mGlu5 positive allosteric modulators (PAM) with with EC50 of 170 nM. |
| PC-63236 |
LY2794193
mGlu3 agonist
|
LY2794193 is a highly potent and selective mGlu3 receptor agonist with Ki of 0.93 nM and EC50 of 47 nM, >100-fold selectivity over mGlu2 receptor. |
| PC-63197 |
VU0424238
mGlu5 NAM
|
Auglurant (VU0424238) is a potent, selective, orally active mGlu5 negative allosteric modulator with Ki of 4.4 nM, displays >900-fold selectivity for mGlu5 versus the other mGlu receptors. |
| PC-43079 |
Methoxy-PEPy
mGlu5 antagonist
|
Methoxy-PEPy is a potent, selective mGlu5 receptor antagonist with IC50 of 1 nM. |
| PC-63181 |
AZD8529 mesylate
mGlu2 PAM
|
AZD8529 mesylate is a potent, selective mGluR2 positive allosteric modulator with EC50 of 195 nM, does not produce any positive allosteric modulator responses for mGluR1 and 3-8 subtypes. |
| PC-63180 |
AZD8529
mGluR2 PAM
|
AZD8529 (AZD-8529) is a novel potent, selective mGluR2 positive allosteric modulator with EC50 of 195 nM, does not produce any positive allosteric modulator responses for mGluR1 and 3-8 subtypes. |
| PC-62985 |
L-AP4
group III mGluR agonist
|
L-AP4 is a selective group III metabotropic glutamate receptor agonist with EC50s of 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6 and mGlu7 receptors, respectively. |
| PC-62984 |
DL-AP4 sodium salt
|
DL-AP4 sodium salt is a broad spectrum glutamate receptor antagonist.. |
| PC-62983 |
LSP4-2022
mGlu4 agonist
|
LSP4-2022 is a novel potent, selective, brain-penetrant mGluR4 agonist with EC50 of 0.11 uM in cell-based assays. |
| PC-62982 |
LSP1-2111
group III mGluR agonist
|
LSP1-2111 is a potent, selective, and brain penetrant group III mGluRs agonist with EC50 of 2.2 and 1.7 uM for mGluR4 and mGluR6, respectively. |
| PC-62958 |
JNJ16567083
mGluR1 antagonist
|
JNJ16567083 (EMQMCM) is a potent and selective mGluR1 antagonist that shows neuroprotective effects in some hypoxia-ischemia models. |
| PC-62957 |
VU0400195
mGluR4 modulator
|
VU0400195 (ML 182) is a potent, selective, brain penetrant and orally active positive allosteric modulator of mGluR4 with EC50 of 291 nM and 376 nM for human and rat mGluR4, respectively. |
