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Cat. No. Product Name Information
PC-21841

AG1478

EGFR inhibitor

AG1478 (Tyrphostin AG-1478) is a potent, selective EGFR tyrosine kinase inhibitor with IC50 of 3 nM.
PC-21465

BI-8128

EGFR inhibitor

BI-8128 is a potent, selective, reversible and orally bioavailable fourth generation EGFR inhibitor, potently inhibits oncogenic EGFR variants del19 and L858R as well as the acquired EGFR resistance mutations T790M and C797S.
PC-21316

EGFR inhibitor 9

EGFR inhibitor

EGFR inhibitor 9 is a potent, selective, brain-penetrant and orally bioavailable EGFR inhibitor, exhibits potent activity in osimertinib-resistant cell lines bearing L858R/C797S and exon19del/C797S EGFR resistance mutations.
PC-21212

MTX-241F

EGFR inhibitor

MTX-241F (MTX241F) is a potent, highly selective and brain-penetrant inhibitor of EGFR, PI3K and DNA-PK with IC50 of 3 nM, 87 nM (PI3Kα) and 5.5 nM, respectively.
PC-20905

SDT-011

EGFR-mAb inhibitor

SDT-011 (SDT011) is a small molecule that effectively blocks the binding of anti-EGFR monoclonal antibodies to EGFR, blocks cetuximab-EGFR binding by 62% at 10 uM, binds to EGFR with Kd of 1.7 nM in MST assays.
PC-20818

HNPMI

EGFR inhibitor

HNPMI is a small molecule inhibitor of epidermal growth factor receptor (EGFR) with the anticancer potential against various cancers.

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