Cat. No. |
Product Name |
Information |
PC-21212 |
MTX-241F
EGFR inhibitor
|
MTX-241F (MTX241F) is a potent, highly selective and brain-penetrant inhibitor of EGFR, PI3K and DNA-PK with IC50 of 3 nM, 87 nM (PI3Kα) and 5.5 nM, respectively. |
PC-20905 |
SDT-011
EGFR-mAb inhibitor
|
SDT-011 (SDT011) is a small molecule that effectively blocks the binding of anti-EGFR monoclonal antibodies to EGFR, blocks cetuximab-EGFR binding by 62% at 10 uM, binds to EGFR with Kd of 1.7 nM in MST assays. |
PC-20818 |
HNPMI
EGFR inhibitor
|
HNPMI is a small molecule inhibitor of epidermal growth factor receptor (EGFR) with the anticancer potential against various cancers. |