EGFR (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-21322	STX-721 EGFR inhibitor	STX-721 is a potent, selective, next-generation, orally active inhibitor of EGFR exon 20 insertion mutations.
PC-21316	EGFR inhibitor 9 EGFR inhibitor	EGFR inhibitor 9 is a potent, selective, brain-penetrant and orally bioavailable EGFR inhibitor, exhibits potent activity in osimertinib-resistant cell lines bearing L858R/C797S and exon19del/C797S EGFR resistance mutations.
PC-21212	MTX-241F EGFR inhibitor	MTX-241F (MTX241F) is a potent, highly selective and brain-penetrant inhibitor of EGFR, PI3K and DNA-PK with IC50 of 3 nM, 87 nM (PI3Kα) and 5.5 nM, respectively.
PC-20905	SDT-011 EGFR-mAb inhibitor	SDT-011 (SDT011) is a small molecule that effectively blocks the binding of anti-EGFR monoclonal antibodies to EGFR, blocks cetuximab-EGFR binding by 62% at 10 uM, binds to EGFR with Kd of 1.7 nM in MST assays.
PC-20818	HNPMI EGFR inhibitor	HNPMI is a small molecule inhibitor of epidermal growth factor receptor (EGFR) with the anticancer potential against various cancers.
PC-73295	DDC-03-024-01 EGFR mutant inhibitor	DDC-03-024-01 is a potent, mutant-selective allosteric inhibitor of EGFR(L858R/T790M) and EGFR(L858R/T790M/C797S) mutants with IC50 of 10 nM.

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