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Cat. No. Product Name Information
PC-72683

GSK3739936

HIV-1 integrase inhibitor

GSK3739936 (BMS-986180) is a potent, allosteric HIV-1 integrase (ALLINI), shows excellent potency in vitro against majority of the 124/125 variants (EC50=1.7 nM).
PC-72633

HIV-1 Integrase inhibitor GS-B

HIV-1 integrase inhibitor

HIV-1 Integrase inhibitor GS-B (GS-B) is a novel non-catalytic site integrase inhibitor of HIV-1 integrase (IN), inhibits the interaction between LEDGF IBD and IN with IC50 of 8.1 nM.
PC-72632

JTP-0157602

HIV-1 integrase inhibitor

JTP-0157602 (JTP0157602) is a novel non-catalytic site integrase inhibitor of HIV-1 integrase (IN), inhibits the interaction between LEDGF IBD and IN with IC50 of 4.2 nM.
PC-72614

NBD-14270

HIV-1 gp120 inhibitor

NBD-14270 (NBD14270) is an HIV-1 gp120 antagonist, shows antiviral activity against HIV-1HXB2 with IC50 of 180 nM.
PC-72601

GSK3640254

HIV-1 maturation inhibitor

GSK3640254 (GSK254, Fipravirimat) is a novel potent HIV-1 maturation inhibitor with EC90 of 33 nM against a minilibrary of clinically relevant HIV-1 polymorphisms in a multiple-cycle assay.
PC-72432

SBI-0637142

Latency-reversing agent

SBI-0637142 is a potent Smac mimetic that preferentially targets BIRC2, latency-reversing agent (LRA), specifically and potently promote HIV-1 latency reversal activity.
PC-72431

Ciapavir

Latency-reversing agent

Ciapavir (SBI-0953294, cIAP1 antagonist for viral reactivation) is a bivalent, next-generation, Smac mimetic and antagonist of cIAP1 as latency-reversing agent (LRA), specifically and potently promote HIV-1 latency reversal activity both in vivo.
PC-38204

FC-8052

HIV-1 Nef inhibitor

FC-8052 (FC8052) is a highly potent inhibitor of HIV-1 Nef-effector kinase, binds to recombinant Nef in vitro with Kd of 10 pM.
PC-38203

SRI-37264

HIV-1 Nef inhibitor

SRI-37264 (SRI 37264) is a small molecule inhibitor of HIV-1 Nef-mediated activation of the myeloid Src-family kinase Hck, blocks HIV-1 replication in macrophages and disrupts MHC-I downregulation.
PC-36113

ZBMA-1

HIV-1 Vif inhibitor

ZBMA-1 is a potent HIV-1 replication inhibitor (IC50=1.01 uM) that efficiently protects APOBEC3G protein by targeting Vif-APOBEC3G complex.
PC-36055

ABX464

Obefazimod (ABX464) is a novel class of anti-HIV small molecule targeting Rev-mediated viral RNA biogenesis, shows dose dependent inhibition of HIV-1 replication in stimulated PBMCs with IC50 of 0.1-0.5 uM.
PC-35935

BMS-818251

HIV-1 inhibitor

BMS-818251 (BMS818251) is a novel potent, small-molecule inhibitor of HIV-1 entry with EC50 of 0.019 nM against e laboratory-adapted HIV-1 strain NL4-3.

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