| Cat. No. |
Product Name |
Information |
| PC-23827 |
Anrikefon acetate
KOR agonist
|
Anrikefon (HSK21542) acetate is a potent, selective and peripherally-restricted kappa opioid receptor (KOR) agonist, prevents [3H]diprenorphine binding to KOR with IC50 of 0.54 nM, and binding Kd of 0.068 nM. |
| PC-23826 |
HSK21542
KOR agonist
|
Anrikefon (HSK21542) is a potent, selective and peripherally-restricted kappa opioid receptor (KOR) agonist, prevents [3H]diprenorphine binding to KOR with IC50 of 0.54 nM, and binding Kd of 0.068 nM. |
| PC-20510 |
AT-076
Pan opioid antagonist
|
AT-076 (AT076) is the first potent small-molecule opioid pan antagonist with receptor binding Ki values of 1.75, 1.14, 1.67 and 19.6 nM for NOP, KOP, MOP, and DOP, respectively. |
| PC-49745 |
RM1490
MOR agonist
|
RM1490 (RM 1490) is a potent, brain-penetrant µ opioid receptor (MOR) agonist with EC50 of 3.4 and 4.4 nM in GTPγS and cAMP assays, respectively. |
| PC-49552 |
DPI-287
DOP agonist
|
DPI-287 is a small-molecule agonist of the δ-opioid receptor (DOP, DOR) with Ki vaule of 0.39 nM, shows 10-fold selectivity for DOP over MOP (Ki=3.17 nM). |
| PC-49035 |
MP135
μ-δ opioid agonist
|
MP135 is a potent, μ-δ opioid receptor heteromer-selective agonist with EC50 of 0.8 nM in GTPγS assays, shows functional selectivity for μ-δ heteromers over homomeric μOR and δOR and low β-arrestin2 recruitment activity. |
| PC-49002 |
PN6047
DOR agonist
|
PN6047 is an orally bioavailable, G protein-biased and selective δ opioid agonist with pKi of 7.25, fully engages G protein signaling but is a partial agonist in both the arrestin recruitment and internalization assays. |
| PC-47026 |
AT-039
NOP agonist
|
AT-039 is a potent, selective agonist of nociceptin opioid peptide (NOP) receptor, AT-039 is useful for treatment of hypertension and/or volume overload/hyponatraemic states. |
| PC-38589 |
BPR1M97
MOP/NOP agonist
|
BPR1M97 is a dual-acting mu-opioid receptor (MOP) and nociceptin-orphanin FQ peptide (NOP) receptor agonist with Ki values of 1.8 and 4.2 nM, respectively. |
| PC-38532 |
BMS 986188
δ-opioid PAM
|
BMS 986188 is a potent, selective positive allosteric modulator of δ-opioid receptor with EC50 of 0.05 uM in β-arrestin recruitment assays, no significant acitivity against μ-opioid receptors. |
| PC-73447 |
Tegileridine
MOR agonist
|
Tegileridine is a selective mu opioid receptor (MOR) agonist with analgesic activity. |
| PC-73442 |
Riminkefon
KOR agonist
|
Riminkefon is a potent kappa opioid receptor (KOR) agonist with analgesic activity. |
