Cat. No. |
Product Name |
Information |
PC-49401 |
SR10221
PPARγ inverse agonist
|
SR10221 is a potent, selective PPARγ inverse agonist with IC50 of 13 nM in biochemical peptide recruitment assays, represses downstream PPARγ target genes leading to growth inhibition in bladder cancer cell lines. |
PC-49400 |
BAY-0069
PPARγ inverse agonist
|
BAY-0069 (BAY0069) is a potent, selective, covalent PPARγ inverse agonist with IC50 of 0.22 nM in cellular reporter assays. |
PC-49036 |
GQ-16
PPARγ agonist
|
GQ-16 is a peroxisome proliferator-activated receptor γ (PPARγ) ligand and partial agonist with Ki value of 160 nM, specific for PPARγ with no detectable activity to activate other PPAR subtypes (PPARα or PPARβ/δ) or RXRα. |
PC-73409 |
Bocidelpar
PPARδ agonist
|
Bocidelpar (ASP-0367, MA-0211, MTB-1) is a potent selective peroxisome proliferator-activated receptor delta (PPARδ) agonist with potential against mitochondrial myopathies. |
PC-73019 |
MSDC0160
MPC inhibitor
|
MSDC0160 (Mitoglitazone, MSDC-0160) is a small molecule targeting mitochondrial pyruvate carrier (MPC), also is an insulin sensitizer with anti-diabetes activities. |
PC-72950 |
PPARγ pSer273-IN-10
PPARγ pSer273 inhibitor
|
PPARγ pSer273-IN-10 is a specific, in vivo-active small molecule inhibitor of CDK5-mediated Ser273 phosphorylation of PPARγ without classical PPARγ agonism. |
PC-38250 |
WO95E
PPARγ agonist
|
WO95E is a novel potent, synthetic ligand (partial agonist) of PPARγ, directly binds to PPARγ with IC50 of 11 nM. |
PC-38051 |
EHP-101
|
EHP-101 (Etrinabdione, VCE-004.8) is an orally active, specific PPARγ and CB2 receptor dual agonist. |
PC-35795 |
Chiglitazar
|
Chiglitazar (Carfloglitazar, CS-038, CS038) is a potent, dual PPARα/γ dual agonist with EC50 of 1.2, 0.08, 1.7 uM for PPARα, PPARγ and PPARδ, respectively. |
PC-43387 |
T0070907
PPARγ inhibitor
|
T0070907 is a potent, selective, covalent PPARγ antagonist with binding IC50 of 1 nM, >800-fold preference for PPARγ over PPARα and PPARδ. |
PC-62872 |
GW-6471
PPARα inhibitor
|
GW-6471 is a potent PPARα antagonist with IC50 of 0.24 uM, enhances the binding affinity of the PPARα ligand-binding domain to the co-repressor proteins SMRT and NCoR.. |
PC-61631 |
ABTL0812
|
ABTL0812 (2-hydroxylinoleic acid) is a novel first-in-class, small molecule that inhibits the Akt/mTORC1 axis and shows antiproliferative effect on tumor cells. |