| Cat. No. |
Product Name |
Information |
| PC-26401 |
RN-1665
TRPV4 antagonist
|
RN-1665 is a potent, selective and orally active TRPV4 antagonist with IC50 of 0.26 μM and 0.39 μM for hTRPV4 and rTRPV4, exhibits excellent selectivity for related TRP receptors such as TRPV1, TRPV3 and TRPM8. |
| PC-26388 |
Isosakuranetin
TRPM3 inhibitor
|
Isosakuranetin is a flavanone natural compound and potent specific inhibitor of TRPM3 with IC50 of 50 nM. |
| PC-26099 |
DWP05195
TRPV1 antagonist
|
DWP05195 (DWP-05195) is a transient receptor potential vanilloid 1 (TRPV1) antagonist. |
| PC-26098 |
Vocacapsaicin hydrochloride
TRPV1 agonist
|
Vocacapsaicin hydrochloride (CA-008) is a non-opioid, water-soluble and injectable prodrug of capsaicin, a potent agonist of TRPV1 channel. |
| PC-25977 |
TRPM8 inhibitor PBMC
TRPM8 antagonist
|
PBMC is a highly specific and potent TRPM8 antagonist with IC50 of 0.4-0.6 nM in whole-cell voltage clamp assays. |
| PC-25933 |
AV3-1
TRPV3 activator
|
AV3-1 (TRPV3 activator 1) is a specific small molecule TRPV3 activator with EC50 of 2.0 μM for mouse TRPV3 and 7.2 μM for human TRPV3. |
| PC-25855 |
Olvanil
TRPV1 agonist
|
Olvanil (NE-19550, N-Vanillyloleamide) is a potent, selective agonist of transient receptor potential vanilloid type 1 (TRPV1) channels with EC50 of 0.7 nM. |
| PC-25854 |
Capsiate
TRPV1 agonist
|
Capsiate is a non-pungent capsaicin analog and potent, selective TRPA1 agonist, evokes inward currents at -60 mV in the HEK293 cells expressing TRPV1with EC50 of 290 nM. |
| PC-25781 |
PPZ2
TRPC3/C6/C7 activator
|
PPZ2 is a selective activator of TRPC3/TRPC6/TRPC7, activates DAG-activated TRPC3/TRPC6/TRPC7 channels, promotes neurite outgrowth and neuronal survival via downstream Ca2+-dependent signals. |
| PC-25780 |
L687
TRPC3/C6/C7 activator
|
L687 is a potent, specific TRPC3/C6/C7 activator, induces cellular antisense oligonucleotide (ASO) uptake, also induces dextran uptake and increases endocytosis. |
| PC-25774 |
Z3571
TRPC6 inhibitor
|
Z3571 is a potent, highly selective and orally bioavailable TRPC6 inhibitor with binding KD of 1.62 uM, inhibits OAG-stimulated Ca2+ influx with IC50 of 31.07 nM, shows >100-fold selectivity over TRPC3 and TRPC7. |
| PC-25552 |
TRPM2 inhibitor LC4
TRPM2 inhibitor
|
TRPM2 inhibitor LC4 is a potent and selective TRPM2 inhibitor with IC50 of 0.66 uM, reduces the infarct volume and oxidative-stress level in transient middle cerebral artery occlusion (tMCAO) model. |
