| Cat. No. |
Product Name |
Information |
| PC-42931 |
SB-366791
TRPV1 antagonist
|
SB-366791 (SB366791) is a potent and selective vanilloid receptor (VR1/TRPV1) antagonist with IC50 of 5.7 nM, also enhances oligodendrocyte formation via HSD17B7 inhibition. |
| PC-42084 |
HC-067047
TRPV4 inhibitor
|
HC-067047 (HC067047) is a potent and selective TRPV4 antagonist with IC50 of 48 nM, 133 nM, and 17 nM for human, rat, and mouse TRPV4 in cell assays, respectively. |
| PC-45632 |
Pyr10
TRPC3 inhibitor
|
Pyr10 is a novel TRPC3-selective inhibitor, inhibits Ca2+ influx in carbachol-stimulated TRPC3-transfected HEK293 cells with IC50 of 0.72 uM. |
| PC-45764 |
BCTC
TRPV1 antagonist
|
BCTC is a highly potent, selective, CNS-penetrant TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 with IC50 values of 35 and 6 nM, respectively. |
| PC-45355 |
Nonivamide
TRPV1 agonist
|
Nonivamide is a capsaicin analog that acts as an agonist of TRPV1 channel. |
| PC-27337 |
TRPV1 agonist MSP20
TRPV1 agonist
|
MSP20 is a potent, selective TRPV1 agonist with EC50 of 46 nM and Emax=78.24%, shows no agonist activity against TRPV3, TRPV4 and TRPM8 receptors. |
| PC-27302 |
TRPV4 antagonist 39
TRPV4 antagonist
|
TRPV4 antagonist 39 is a potent, selective TRPV4 antagonist with IC50 of 0.2 nM. |
| PC-27188 |
9-phenanthrol
TRPM4 inhibitor
|
9-Phenanthrol (9-Hydroxyphenanthrene) is a specific, reversible small molecule TRPM4 inhibitor with IC50 of 17 uM, is ineffective on the related channel TRPM5. |
| PC-26841 |
Ononetin
TRPM3 antagonist
|
Ononetin is a deoxybenzoin from Ononis spinosa and selective TRPM3 antagonist with IC50 of 0.3 uM. |
| PC-26530 |
CMP233
TRPM4 antagonist
|
CMP233 is a potent, selective TRPM4 channel antagonist with IC50 of 0.15 uM. |
| PC-26527 |
TRPM4 inhibitor PBA
TRPM4 inhibitor
|
TRPM4 inhibitor PBA is a specific small molecule inhibitor of Ca2+-activated monovalent cation channel TRPM4 with IC50 of 339 nM using the fluorescence-based Na+-influx assay on HEK293 cells stably overexpressing hTRPM4. |
| PC-26459 |
IMTU
TRPV1 antagonist
|
IMTU is a potent and selective TRPV1 antagonist with IC50 of 128.34 nM, significantly inhibits the capsaicin-induced calcium influx. |
