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Cat. No. Product Name Information
PC-22981

Capsazepine

TRPV1 antagonist

Capsazepine is a selective antagonist of vanilloid receptor TRPV1 with IC50 of 562 nM.
PC-22742

GSK3491943

TRPV4 inhibitor

GSK3491943 is a potent, selective TRPV4 inhibitor with IC50 of 3.2 nM (hTRPV4).
PC-22421

TRPV1 antagonist CX-3

TRPV1 antagonist

TRPV1 antagonist CX-3 is a first-in-class highly selective TRPV1 antagonist with IC50 of 26.2 nM, inhibits TRPV1 current with IC50 value of 9.71 uM in whole-cell patch-clamp assay.
PC-22256

TRPM5 agonist 64

TRPM5 agonist

TRPM5 agonist 64 is a potent, selective TRPM5 agonist with pEC50 of 7.8 and .1 for mTRPM5 and hTRPM5, respectively.
PC-22170

TRPV2 antagonist SET2

TRPV2 antagonist

SET2 is a potent, subtype-selective inhibitor of transient receptor potential vanilloid type 2 (TRPV2) with IC50 of 0.46 uM.
PC-22127

SOR-C13 TFA

TRPV6 inhibitor

SOR-C13 TFA, a carboxy-terminal truncated peptide, is a high-affinity, selective TRPV6 calcium channel inhibitor with IC50 of 14 nM.
PC-22083

PCC0208057

TRPC6 inhibitor

PCC0208057 is a potent, selective TRPC6 channel inhibitor, inhibits TRPC6-mediated Ca2+ concentration increase with IC50 of 2.44 uM, binds directly to TRPC6.
PC-21342

Hyperforin Dicyclohexylammonium Salt

TRPC6 activator

Hyperforin Dicyclohexylammonium Salt is a small molecule activator of TRPC6, elevates intracellular Ca2+ concentrations by activating TRPC6 channels while not activating other TRPC isoforms.
PC-21131

AAL-149

TRPM7 inhibitor

AAL-149 is a non-phosphorylatable FTY720 analogue and novel TRPM7 inhibitor, inhibits IM7 in a dose-dependent manner with IC50 of 1.081 uM, shows potent anti-inflammatory effects in vivo.
PC-21060

MK6-83

TRPML1 agonist

MK6-83 is a specific transient receptor potential mucolipin -1 (TRPML1/MCOLN1) agonist, activates the entire endosomal TRPML1 current in DMD myocytes with EC50 of 285 nM.
PC-49443

AMG21629

TRPV1 antagonist

AMG21629 is a potent and selective TRPV1 antagonist, inhibits Ca2+ uptake by CHO cells expressing TRPV1 receptors with IC50 of 0.6 nM and 0.8 nM for capsaicin and acid-induced Ca2+ uptake, respectively.
PC-73173

ML-SI3

TRPML inhibitor

ML-SI3 is a synthetic inhibitor of TRPML calcium channel blocker.

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