| Cat. No. |
Product Name |
Information |
| PC-25400 |
Br-cis-22a
TRPV6 inhibitor
|
Br-cis-22a is a brominated PCHPD analog of TRPV6 inhibitor cis-22a, inhibits uptake of Cd2+ into hTRPV6-expressing HEK 293 cells with IC50 of 0.96 uM. |
| PC-25399 |
TRPV6 inhibitor cis-22a TFA
TRPV6 inhibitor
|
TRPV6 inhibitor cis-22a TFA is a potent, selective inhibitor of TRPV6 calcium channel with IC50 of 0.32 uM, shows high selectivity against other calcium channels and related TRP targets, selectively reduces cancer cell growth on TRPV6 positive (T47D) breast cancer cells. |
| PC-25398 |
TRPV6 inhibitor cis-22a
TRPV6 inhibitor
|
TRPV6 inhibitor cis-22a is a potent, selective inhibitor of TRPV6 calcium channel with IC50 of 0.32 uM, shows high selectivity against other calcium channels and related TRP targets, selectively reduces cancer cell growth on TRPV6 positive (T47D) breast cancer cells. |
| PC-25086 |
ML2-SA2
TRPML2 agonist
|
ML2-SA2 is a selective, small-molecule TRPML2 channel agonist with EC50 of 6.4 uM, while inhibiting TRPML1 and TRPML3 with IC50 of 2.3 uM and 15.9 uM, respectively. |
| PC-25031 |
Apecotrep
TRPC6 inhibitor
|
Apecotrep (TRPC6-IN-3) is a potent, orally active transient receptor potential C6 ion channel (TRPC6) inhibitor. |
| PC-24809 |
AP-18
TRPA1 inhibitor
|
AP-18 is a potent and selective TRPA1 inhibitor, blocks activation of TRPA1 by 50 μM Cinnamaldehyde with IC50 of 3.1 uM and 4.5 μM for human and mouse TRPA1 respectively. |
| PC-24742 |
Resiniferatoxin
TRPV1 agonist
|
Resiniferatoxin ((+)-Resiniferatoxin) is a high affinity, selective agonist of transient receptor potential vanilloid 1 (TRPV1), binds HEK293/VR1 cells and CHO/VR1 cells with affinities of 84 and 103 pM, respectively. |
| PC-24729 |
CIM0216
TRPM3 agonist
|
CIM0216 is a potent, selective synthetic TRPM3 activator / agonist, evokes robust increases in intracellular Ca2+ concentration in HEK-TRPM3 cells with EC50 of 0.77 uM. |
| PC-24333 |
TRPM8 antagonist 23
TRPM8 antagonist
|
TRPM8 antagonist 23 is a potent and selective TRPM8 antagonist with IC50 of 0.2 uM, 10-fold higher potency for human TRPM8 (hTRPM8) than for hTRPV1 and hTRPA1 channels. |
| PC-23886 |
TRPM4 inhibitor IBA
TRPM4 inhibitor
|
TRPM4 inhibitor IBA is a potent and selective inhibitor of the cation channel TRPM4 with IC50 of 142 nM. |
| PC-23885 |
TRPM4 inhibitor CBA
TRPM4 inhibitor
|
TRPM4 inhibitor CBA is a potent and selective inhibitor of the cation channel TRPM4 with IC50 of 1.5 uM. |
| PC-23884 |
TRPM4 inhibitor NBA
TRPM4 inhibitor
|
TRPM4 inhibitor NBA is a potent, selective transient receptor potential melastatin 4 (TRPM4) inhibitor with IC50 value of 0.16 uM. |
