| Cat. No. |
Product Name |
Information |
| PC-49275 |
KS0365
TRPV3 activator
|
KS0365 (KS 0365) is a potent and selective activator of transient receptor potential vanilloid 3 (TRPV3) channel with EC50 of 5.08 uM. |
| PC-38809 |
GNE551
TRPA1 agonist
|
GNE551 is a potent, selective, non-covalent agonist of TRPA1 ion channel with EC50 of 254 nM in Ca2+ influx assays. |
| PC-38378 |
CA-008
TRPV1 agonist
|
CA-008 (Vocacapsaicin) is a non-opioid, water-soluble and injectable prodrug of capsaicin, a potent agonist of TRPV1 channel. |
| PC-73245 |
GFB-8438
TRPC5 inhibitor
|
GFB-8438 is a potent, selective TRPC5 inhibitor with IC50 of 0.18 uM (hTRPC5, Qpatch assay). |
| PC-73026 |
ML-SI3
TRPML1 antagonist
|
ML-SI3 (Mucolipin-specific synthetic inhibitor 3) is a synthetic antagonist of transient receptor potential mucolipin 1 (TRPML1), prevents lysosomal calcium efflux and blocks downstream TRPML1-mediated induction of autophagy. |
| PC-73025 |
ML-SA1
TRPML1 agonist
|
ML-SA1 (Mucolipin-specific synthetic agonist 1) is a potent synthetic agonist for TRPML1. |
| PC-72922 |
JW-65
TRPC3 inhibitor
|
JW-65 (JW65) is a selective, potent, CNS-permeable TRPC3 inhibitor improved stability compared to Pyr3. |
| PC-72671 |
ML2-SA1
TRPML2 agonist
|
ML2-SA1 is a potent, selective and efficacious activator (agonist) of TRPML2 with EC50 of 1.24 uM and 2.38 uM for human and mouse TRPML2, respectively. |
| PC-72599 |
GSK2798745
TRPV4 inhibitor
|
GSK2798745 (GSK-2798745) is a potent, selective TRPV4 inhibitor with IC50 of 1.8/1.6 nM (hTRPV4/rTRPV4). |
| PC-72566 |
SH045
TRPC6 inhibitor
|
SH045 (SH-045, Larixyl-6-N-methylcarbamate) is a potent, selective TRPC6 antagonist (blocker) with IC50 of 63 nM. |
| PC-72565 |
BI-749327
TRPC6 blocker
|
BI-749327 (BI 749327) is a potent, selective orally bioavailable TRPC6 antagonist (blocker) with IC50 of 13/19/15 nM for mouse/human/guinea pig TRPC6, respectively. |
| PC-72564 |
CDD-1102
BRDT BD2 inhibitor
|
CDD-1102 (CDD1102) is a potent, selective second bromodomain (BD2) of BRDT and BRD4 inhibitor with IC50 of 7 and 25 nM, >1,000-fold and 300-fold selectivity over BRDT-BD1 and BRD4-BD1. |
