| Cat. No. |
Product Name |
Information |
| PC-49684 |
JT010
TRPA1 agonist
|
JT010 (JT-010) is a potent, site-selective and covalent TRPA1 agonist, opens the TRPA1 channel by covalently and site-selectively binding to Cys621 with EC50 of 0.65 nM. |
| PC-49536 |
TRPM5 agonist 39
TRPM5 agonist
|
TRPM5 agonist 39 is a potent, selective transient receptor potential cation channel subfamily M member 5 (TRPM5) agonist with pEC50 of 7.1, shows high selectivity over TRPA1, TRPV1, TRPV4, TRPM4 and TRPM8. |
| PC-49411 |
Trpvicin
TRPV3 inhibitor
|
Trpvicin is a potent and subtype-selective inhibitor of TRPV3 with IC50 of 0.41 and 0.22 uM for hTRPV3-WT and hTRPV3-G573S mutant, respectively. |
| PC-49275 |
KS0365
TRPV3 activator
|
KS0365 (KS 0365) is a potent and selective activator of transient receptor potential vanilloid 3 (TRPV3) channel with EC50 of 5.08 uM. |
| PC-47023 |
JNc-463
TRPV4-eNOS activator
|
JNc-463 is a small-molecule that could increase the TRPV4-eNOS interaction, enhances vasodilation and exert antihypertensive effects in mice. |
| PC-38809 |
GNE551
TRPA1 agonist
|
GNE551 is a potent, selective, non-covalent agonist of TRPA1 ion channel with EC50 of 254 nM in Ca2+ influx assays. |
| PC-38676 |
Libvatrep
TRPV1 antagonist
|
Libvatrep (SAF312) is a potent, selective non-competitive inhibitor/antagonist of the transient receptor potential cation channel subfamily V member 1 (TRPV1), shows potential for treatment of ocular surface pain. |
| PC-38603 |
Mesendogen
TRPM6 inhibitor
|
Mesendogen (Compound 6528694, MEG) is a small molecule inhibitor of TRPM6 channel, promotes mesoderm and definitive endoderm differentiation of human embryonic stem cells (hESCs) through alteration of magnesium homeostasis. |
| PC-38390 |
Evifacotrep
TRPC5 inhibitor
|
Evifacotrep is a potent selective transient receptor potential channel 5 (TRPC5) antagonist. |
| PC-38378 |
CA-008
TRPV1 agonist
|
CA-008 (Vocacapsaicin) is a non-opioid, water-soluble and injectable prodrug of capsaicin, a potent agonist of TRPV1 channel. |
| PC-73430 |
Motugivatrep
TRPV1 antagonist
|
Motugivatrep is a potent, selective transient receptor potential vanilloid 1 (TRPV1) antagonist. |
| PC-73351 |
ZINC17988990
TRPV5 inhibitor
|
ZINC 17988990 is a potent, selective inhibitor of TRPV5 mediated currents, inhibits rbTRPV5/hTRPV5 with IC50 of 106/177 nM, showing marked selectivity for TRPV5 over TRPV6. |
