| Cat. No. |
Product Name |
Information |
| PC-45355 |
Nonivamide
TRPV1 agonist
|
Nonivamide is a capsaicin analog that acts as an agonist of TRPV1 channel. |
| PC-24333 |
TRPM8 antagonist 23
TRPM8 antagonist
|
TRPM8 antagonist 23 is a potent and selective TRPM8 antagonist with IC50 of 0.2 uM, 10-fold higher potency for human TRPM8 (hTRPM8) than for hTRPV1 and hTRPA1 channels. |
| PC-23886 |
TRPM4 inhibitor IBA
TRPM4 inhibitor
|
TRPM4 inhibitor IBA is a potent and selective inhibitor of the cation channel TRPM4 with IC50 of 142 nM. |
| PC-23885 |
TRPM4 inhibitor CBA
TRPM4 inhibitor
|
TRPM4 inhibitor CBA is a potent and selective inhibitor of the cation channel TRPM4 with IC50 of 1.5 uM. |
| PC-23884 |
TRPM4 inhibitor NBA
TRPM4 inhibitor
|
TRPM4 inhibitor NBA is a potent, selective transient receptor potential melastatin 4 (TRPM4) inhibitor with IC50 value of 0.16 uM. |
| PC-23880 |
Englerin A
TRPC4/5 agonist
|
Englerin A is a selective inhibitor of renal cancer cell growth with GI50 of 1-87 nM, also is a potent agonist of TRPC ion channels containing TRPC4 and TRPC5 subunits. |
| PC-23871 |
Primidone
TRPM3 inhibitor
|
Primidone is an anticonvulsant agent and highly efficient, selective TRPM3 blocker IC50 of 0.6 uM and marked specificity for TRPM3. |
| PC-23865 |
ELP-004
TRPC inhibitor
|
ELP-004 is a small molecule inhibitor of transient receptor potential canonical (TRPC) channels, inhibits TRPC channel–mediated Ca2+ entry with high potency, preferentially inhibits inflammatory cytokine-induced pathological osteoclastogenesis. |
| PC-23765 |
Naltriben mesylate
TRPM7 agonist
|
Naltriben mesylate is a potent, selective delta-opioid receptor (DOR) antagonist with Ki of 0.013 nM, also is a potent TRPM7 agonist. |
| PC-23622 |
LY3526318
TRPA1 antagonist
|
LY3526318 is an orally bioavailable, potent, and selective TRPA1 antagonist with limited penetration to the central nervous system, effectively blocks cinnamaldehyde-evoked activation of rat and human TRPA1. |
| PC-23550 |
Pyr3
TRPC3 inhibitor
|
Pyr3 is a potent, selective inhibitor of transient receptor potential canonical channel 3 (TRPC3) with IC50 of 700 nM for inhibition of TRPC3-mediated Ca2+ influx. |
| PC-23230 |
Plumbagin
TRPV2 inhibitor
|
Plumbagin (2-Methyljuglone) is a naphthoquinone isolated from Plumbago zeylanica, exhibits anticancer and antiproliferative activities, also is a potent TRPV2 negative allosteric modulator with IC50 of 0.85 μM, exhibiting >14-fold selectivity over TRPV1, TRPV3 and TRPV4. |
