| Cat. No. |
Product Name |
Information |
| PC-45632 |
Pyr10
TRPC3 inhibitor
|
Pyr10 is a novel TRPC3-selective inhibitor, inhibits Ca2+ influx in carbachol-stimulated TRPC3-transfected HEK293 cells with IC50 of 0.72 uM. |
| PC-45764 |
BCTC
TRPV1 antagonist
|
BCTC is a highly potent, selective, CNS-penetrant TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 with IC50 values of 35 and 6 nM, respectively. |
| PC-45355 |
Nonivamide
TRPV1 agonist
|
Nonivamide is a capsaicin analog that acts as an agonist of TRPV1 channel. |
| PC-24742 |
Resiniferatoxin
TRPV1 agonist
|
Resiniferatoxin ((+)-Resiniferatoxin) is a high affinity, selective agonist of transient receptor potential vanilloid 1 (TRPV1), binds HEK293/VR1 cells and CHO/VR1 cells with affinities of 84 and 103 pM, respectively. |
| PC-24729 |
CIM0216
TRPM3 agonist
|
CIM0216 is a potent, selective synthetic TRPM3 activator / agonist, evokes robust increases in intracellular Ca2+ concentration in HEK-TRPM3 cells with EC50 of 0.77 uM. |
| PC-24333 |
TRPM8 antagonist 23
TRPM8 antagonist
|
TRPM8 antagonist 23 is a potent and selective TRPM8 antagonist with IC50 of 0.2 uM, 10-fold higher potency for human TRPM8 (hTRPM8) than for hTRPV1 and hTRPA1 channels. |
| PC-23886 |
TRPM4 inhibitor IBA
TRPM4 inhibitor
|
TRPM4 inhibitor IBA is a potent and selective inhibitor of the cation channel TRPM4 with IC50 of 142 nM. |
| PC-23885 |
TRPM4 inhibitor CBA
TRPM4 inhibitor
|
TRPM4 inhibitor CBA is a potent and selective inhibitor of the cation channel TRPM4 with IC50 of 1.5 uM. |
| PC-23884 |
TRPM4 inhibitor NBA
TRPM4 inhibitor
|
TRPM4 inhibitor NBA is a potent, selective transient receptor potential melastatin 4 (TRPM4) inhibitor with IC50 value of 0.16 uM. |
| PC-23880 |
Englerin A
TRPC4/5 agonist
|
Englerin A is a selective inhibitor of renal cancer cell growth with GI50 of 1-87 nM, also is a potent agonist of TRPC ion channels containing TRPC4 and TRPC5 subunits. |
| PC-23871 |
Primidone
TRPM3 inhibitor
|
Primidone is an anticonvulsant agent and highly efficient, selective TRPM3 blocker IC50 of 0.6 uM and marked specificity for TRPM3. |
| PC-23865 |
ELP-004
TRPC inhibitor
|
ELP-004 is a small molecule inhibitor of transient receptor potential canonical (TRPC) channels, inhibits TRPC channel–mediated Ca2+ entry with high potency, preferentially inhibits inflammatory cytokine-induced pathological osteoclastogenesis. |
