| Cat. No. |
Product Name |
Information |
| PC-42017 |
SKF-96365 hydrochloride
|
SKF-96365 hydrochloride (SKF96365) is potent inhibitor of receptor-mediated calcium entry (RMCE) with IC50 of 8.5 and 11.7 uM for inhibition in platelets stimulated with ADP and thrombin, respectively. |
| PC-42084 |
HC-067047
TRPV4 inhibitor
|
HC-067047 (HC067047) is a potent and selective TRPV4 antagonist with IC50 of 48 nM, 133 nM, and 17 nM for human, rat, and mouse TRPV4 in cell assays, respectively. |
| PC-45632 |
Pyr10
TRPC3 inhibitor
|
Pyr10 is a novel TRPC3-selective inhibitor, inhibits Ca2+ influx in carbachol-stimulated TRPC3-transfected HEK293 cells with IC50 of 0.72 uM. |
| PC-45764 |
BCTC
TRPV1 antagonist
|
BCTC is a highly potent, selective, CNS-penetrant TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 with IC50 values of 35 and 6 nM, respectively. |
| PC-45355 |
Nonivamide
TRPV1 agonist
|
Nonivamide is a capsaicin analog that acts as an agonist of TRPV1 channel. |
| PC-22170 |
TRPV2 antagonist SET2
TRPV2 antagonist
|
SET2 is a potent, subtype-selective inhibitor of transient receptor potential vanilloid type 2 (TRPV2) with IC50 of 0.46 uM. |
| PC-22128 |
TH-1177
TRPV6 inhibitor
|
TH-1177 is a small molecule TRPV6 calcium channel inhibitor, effectively blocks calcium entry in LNCaP prostate cancer cells and demonstrates inhibitory effects on prostate cancer proliferation. |
| PC-22127 |
SOR-C13 TFA
TRPV6 inhibitor
|
SOR-C13 TFA, a carboxy-terminal truncated peptide, is a high-affinity, selective TRPV6 calcium channel inhibitor with IC50 of 14 nM. |
| PC-22083 |
PCC0208057
TRPC6 inhibitor
|
PCC0208057 is a potent, selective TRPC6 channel inhibitor, inhibits TRPC6-mediated Ca2+ concentration increase with IC50 of 2.44 uM, binds directly to TRPC6. |
| PC-21908 |
GDC-6599
TRPA1 inhibitor
|
GDC-6599 is a potent, selective transient receptor potential ankyrin 1 (TRPA1) antagonist with IC50 of 5.3 nM (hTRPA1), exhibits TRPA1 cell potency (IC50=20 nM) in the Ca2+ influx assay in CHO cells. |
| PC-21344 |
M085
TRPC3/6/7 activator
|
M085 (TRPC3/6/7 activator 4o) is a potent and selective TRPC3/6/7 activator with EC50 of 4.66 uM, also activates hTRPC6 with EC50 of 3.8 uM. |
| PC-21342 |
Hyperforin Dicyclohexylammonium Salt
TRPC6 activator
|
Hyperforin Dicyclohexylammonium Salt is a small molecule activator of TRPC6, elevates intracellular Ca2+ concentrations by activating TRPC6 channels while not activating other TRPC isoforms. |
