| Cat. No. |
Product Name |
Information |
| PC-60294 |
GSK2193874
TRPV4 inhibitor
|
GSK2193874 (GSK 2193874) is an orally active, potent, and selective blocker of TRPV4 channel with IC50 of 40 nM and 2 nM for hTRPV4 and rTRPV4, respectively. |
| PC-70051 |
A-967079
TRPA1 inhibitor
|
A-967079 (A 967079) is a potent, selective TRPA1 channel blocker with IC50 of 51 nM and 101 nM for hTRPA1 and rTRPA1, respectively. |
| PC-70040 |
RN-9893 hydrochloride
TRPV4 inhibitor
|
RN-9893 hydrochloride is a potent, selective orally-bioavailable TRPV4 antagonist with IC50 of 320, 420 and 660 nM for mouse, human and rat TRPV4 channels, respectively. |
| PC-70039 |
RN-9893
TRPV4 inhibitor
|
RN-9893 (RN9893) is a potent, selective orally-bioavailable TRPV4 antagonist with IC50 of 320, 420 and 660 nM for mouse, human and rat TRPV4 channels, respectively. |
| PC-60025 |
AC1903
|
AC1903 is a potent, specific TRPC5 channel inhibitor with IC50 of 14.7 uM. |
| PC-60019 |
2-APB
TRP channel inhibitor
|
2-APB (2-Aminoethoxydiphenylborane) is a membrane permeable IP3 receptor antagonist and broad TRP channels (TRPC5, TRPM2) blocker. |
| PC-45654 |
GSK1016790A
TRPV4 agonist
|
GSK1016790A is a potent TRPV4 channel agonist, induces Ca2+ influx in HEK cells expressing human TRPV4 with EC50 of 2.1 nM. |
| PC-45790 |
Clemizole hydrochloride
TRPC5 inhibitor
|
Clemizole hydrochloride is an H1 histamine receptor antagonist that substantially inhibits HCV replication by suppression of NS4B's RNA binding (IC50=24 nM) with little toxicity for the host cells. |
| PC-45789 |
Clemizole
TRPC5 inhibitor
|
An H1 histamine receptor antagonist that substantially inhibits HCV replication by suppression of NS4B's RNA binding (IC50=24 nM) with little toxicity for the host cells. |
| PC-42591 |
Capsaicin
TRPV1 agonist
|
Capsaicin is an active component of chili pepper, potent agonist of TRPV1 channel with EC50 of 0.29 uM. |
| PC-42799 |
Icilin
TRPM8 agonist
|
Icilin (AG-3-5) is asuper-cooling agent that fuctions as a potent TRPM8 agonist with EC50 of 0.2 uM. |
| PC-45042 |
SN-2
TRPML3 activator
|
SN-2 (TRPML3 activator SN-2) is a small molecule activator of the TRPML3 ion channel with EC50 of 1.13 uM strongly potentiates TRPML3 activation with low extracytosolic [Na(+)]. |
