| Cat. No. |
Product Name |
Information |
| PC-42688 |
SB-705498
TRPV1 antagonist
|
SB-705498 (SB705498) is a potent, selective and orally bioavailable TRPV1 antagonist with pKi of 7.6 (inhibition of capsaicin-mediated activation of hTRPV1 receptor). |
| PC-42419 |
AMG-9810
TRPV1 inhibitor
|
AMG-9810 is a potent, selective and competitive TRPV1 antagonist with IC50 of 24.5 and 85.6 nM for human and rat TRPV1, respectively. |
| PC-45556 |
PF-4840154
TRPA1 agonist
|
PF-4840154 is a potent, selective agonist of the rat (EC50=97 nM) and human (EC50=23 nM) TRPA1 channel. |
| PC-42017 |
SKF-96365 hydrochloride
|
SKF-96365 hydrochloride (SKF96365) is potent inhibitor of receptor-mediated calcium entry (RMCE) with IC50 of 8.5 and 11.7 uM for inhibition in platelets stimulated with ADP and thrombin, respectively. |
| PC-42689 |
AMG517
TRPV1 antagonist
|
AMG517 is a potent and selective vanilloid receptor TRPV1 antagonist with IC50 of 0.76 nM for hTRPV |
| PC-42931 |
SB-366791
TRPV1 antagonist
|
SB-366791 (SB366791) is a potent and selective vanilloid receptor (VR1/TRPV1) antagonist with IC50 of 5.7 nM. |
| PC-42084 |
HC-067047
TRPV4 inhibitor
|
HC-067047 (HC067047) is a potent and selective TRPV4 antagonist with IC50 of 48 nM, 133 nM, and 17 nM for human, rat, and mouse TRPV4 in cell assays, respectively. |
| PC-45632 |
Pyr10
TRPC3 inhibitor
|
Pyr10 is a novel TRPC3-selective inhibitor, inhibits Ca2+ influx in carbachol-stimulated TRPC3-transfected HEK293 cells with IC50 of 0.72 uM. |
| PC-45764 |
BCTC
TRPV1 antagonist
|
BCTC is a highly potent, selective, CNS-penetrant TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 with IC50 values of 35 and 6 nM, respectively. |
| PC-45355 |
Nonivamide
TRPV1 agonist
|
Nonivamide is a capsaicin analog that acts as an agonist of TRPV1 channel. |
| PC-22421 |
TRPV1 antagonist CX-3
TRPV1 antagonist
|
TRPV1 antagonist CX-3 is a first-in-class highly selective TRPV1 antagonist with IC50 of 26.2 nM, inhibits TRPV1 current with IC50 value of 9.71 uM in whole-cell patch-clamp assay. |
| PC-22256 |
TRPM5 agonist 64
TRPM5 agonist
|
TRPM5 agonist 64 is a potent, selective TRPM5 agonist with pEC50 of 7.8 and .1 for mTRPM5 and hTRPM5, respectively. |
