| Cat. No. |
Product Name |
Information |
| PC-60019 |
2-APB
TRP channel inhibitor
|
2-APB (2-Aminoethoxydiphenylborane) is a membrane permeable IP3 receptor antagonist and broad TRP channels (TRPC5, TRPM2) blocker. |
| PC-45654 |
GSK1016790A
TRPV4 agonist
|
GSK1016790A is a potent TRPV4 channel agonist, induces Ca2+ influx in HEK cells expressing human TRPV4 with EC50 of 2.1 nM. |
| PC-45790 |
Clemizole hydrochloride
TRPC5 inhibitor
|
Clemizole hydrochloride is an H1 histamine receptor antagonist that substantially inhibits HCV replication by suppression of NS4B's RNA binding (IC50=24 nM) with little toxicity for the host cells. |
| PC-45789 |
Clemizole
TRPC5 inhibitor
|
An H1 histamine receptor antagonist that substantially inhibits HCV replication by suppression of NS4B's RNA binding (IC50=24 nM) with little toxicity for the host cells. |
| PC-42591 |
Capsaicin
TRPV1 agonist
|
Capsaicin is an active component of chili pepper, potent agonist of TRPV1 channel with EC50 of 0.29 uM. |
| PC-42799 |
Icilin
TRPM8 agonist
|
Icilin (AG-3-5) is asuper-cooling agent that fuctions as a potent TRPM8 agonist with EC50 of 0.2 uM. |
| PC-45042 |
SN-2
TRPML3 activator
|
SN-2 (TRPML3 activator SN-2) is a small molecule activator of the TRPML3 ion channel with EC50 of 1.13 uM strongly potentiates TRPML3 activation with low extracytosolic [Na(+)]. |
| PC-45093 |
Mavatrep
TRPV1 inhibitor
|
Mavatrep (JNJ-39439335) is a selective, high-affinity TRPV1 antagonist with IC50 of 4.6 nM (inhibition of capsaicin-induced Ca(2+) influx). |
| PC-45772 |
RN-1734
TRPV4 inhibitor
|
RN-1734 (RN1734) is a potent, selective TRPV4 antagonist with IC50 of 2.3, 3.2 and 5.9 uM for hTRPV4, rTRPV4 and mTRPV4 channels, respectively. |
| PC-42062 |
JNJ-17203212
TRPV1 antagonist
|
JNJ-17203212 is a potent, selective and orally bioavailable TRPV1 receptor antagonist with IC50 of 65 nM and 102 nM for hTRPV1 and rTRPV1, respectively. |
| PC-42688 |
SB-705498
TRPV1 antagonist
|
SB-705498 (SB705498) is a potent, selective and orally bioavailable TRPV1 antagonist with pKi of 7.6 (inhibition of capsaicin-mediated activation of hTRPV1 receptor). |
| PC-42419 |
AMG-9810
TRPV1 inhibitor
|
AMG-9810 is a potent, selective and competitive TRPV1 antagonist with IC50 of 24.5 and 85.6 nM for human and rat TRPV1, respectively. |
