| Cat. No. |
Product Name |
Information |
| PC-49275 |
KS0365
TRPV3 activator
|
KS0365 (KS 0365) is a potent and selective activator of transient receptor potential vanilloid 3 (TRPV3) channel with EC50 of 5.08 uM. |
| PC-47023 |
JNc-463
TRPV4-eNOS activator
|
JNc-463 is a small-molecule that could increase the TRPV4-eNOS interaction, enhances vasodilation and exert antihypertensive effects in mice. |
| PC-38676 |
Libvatrep
TRPV1 antagonist
|
Libvatrep (SAF312) is a potent, selective non-competitive inhibitor/antagonist of the transient receptor potential cation channel subfamily V member 1 (TRPV1), shows potential for treatment of ocular surface pain. |
| PC-38603 |
Mesendogen
TRPM6 inhibitor
|
Mesendogen (Compound 6528694, MEG) is a small molecule inhibitor of TRPM6 channel, promotes mesoderm and definitive endoderm differentiation of human embryonic stem cells (hESCs) through alteration of magnesium homeostasis. |
| PC-38390 |
Evifacotrep
TRPC5 inhibitor
|
Evifacotrep is a potent selective transient receptor potential channel 5 (TRPC5) antagonist. |
| PC-73430 |
Motugivatrep
TRPV1 antagonist
|
Motugivatrep is a potent, selective transient receptor potential vanilloid 1 (TRPV1) antagonist. |
| PC-73351 |
ZINC17988990
TRPV5 inhibitor
|
ZINC 17988990 is a potent, selective inhibitor of TRPV5 mediated currents, inhibits rbTRPV5/hTRPV5 with IC50 of 106/177 nM, showing marked selectivity for TRPV5 over TRPV6. |
| PC-73173 |
ML-SI3
TRPML inhibitor
|
ML-SI3 is a synthetic inhibitor of TRPML calcium channel blocker. |
| PC-73096 |
GSK3527497
TRPV4 inhibitor
|
GSK3527497 (GSK-3527497) is a potent, selective TRPV4 inhibitor with IC50 of 12 nM (hTRPV4). |
| PC-72671 |
ML2-SA1
TRPML2 agonist
|
ML2-SA1 is a potent, selective and efficacious activator (agonist) of TRPML2 with EC50 of 1.24 uM and 2.38 uM for human and mouse TRPML2, respectively. |
| PC-72566 |
SH045
TRPC6 blocker
|
SH045 (SH-045, Larixyl-6-N-methylcarbamate) is a potent, selective TRPC6 antagonist (blocker) with IC50 of 63 nM. |
| PC-72564 |
CDD-1102
BRDT BD2 inhibitor
|
CDD-1102 (CDD1102) is a potent, selective second bromodomain (BD2) of BRDT and BRD4 inhibitor with IC50 of 7 and 25 nM, >1,000-fold and 300-fold selectivity over BRDT-BD1 and BRD4-BD1. |
