| Cat. No. |
Product Name |
Information |
| PC-62627 |
GSK205
|
GSK205 is a selective small molecule TRPV4 channel inhibitor with IC50 of 4.19 uM. |
| PC-62012 |
ADM 12
|
ADM 12 (ADM_12. |
| PC-61767 |
JNc-440
|
JNc-440 is a small molecule that significantly and specifically strengthens the TRPV4-KCa2.3 interaction in mouse endothelial cells, but does not systemically activate TRPV4 and KCa2.3. |
| PC-61534 |
V-116517
|
V-116517 is a novel potent, selective, oral bioavailable TRPV1 antagonist with IC50 of 35.1 nM. |
| PC-61533 |
ABT-102
|
ABT-102 is a potent, highly selective, orally active TRPV1 antagonist that inhibits agonist-evoked increases in intracellular Ca(2+) levels with IC50 of 5-7 nM. |
| PC-61374 |
Elismetrep
|
A novel specific TRPM8 channel antagonist for treatment or prevention vasomotor symptoms.. |
| PC-61156 |
ASP 7663
|
A novel potent, selective, orally active TRPA1 receptor agonist with EC50 of 0.51, 0.54 and 0.50 uM for human, rat and mouse TRPA1, respectively. |
| PC-60788 |
(S)-PBMC
|
A novel potent, selective TRPM8 antagonist with IC50 of 15.6 nM (hTRPM8). |
| PC-60786 |
WS-12
|
A potent, selective TRPM8 agonist with EC50 of 12 uM, a cooling agent. |
| PC-60742 |
DFL 23448
|
A novel potent, selective TRPM8 channel antagonist with IC50 of 10 and 21 nM in hTRPM8 HEK293 cells activated by Cooling Agent 10 or cold. |
| PC-60719 |
JNJ 41876666
|
A potent, selective, orally active TRPM8 channel antaognist with IC50 of 0.8 nM, . |
| PC-60718 |
AMTB hydrochloride
|
A selective TRPM8 channel blocker with pEC50 of 6.91 in Ca(2+) influx assay, with no activity for TRPV4 (pEC50<4.6). |
