| Cat. No. |
Product Name |
Information |
| PC-26459 |
IMTU
TRPV1 antagonist
|
IMTU is a potent and selective TRPV1 antagonist with IC50 of 128.34 nM, significantly inhibits the capsaicin-induced calcium influx. |
| PC-26458 |
HKC54
TRPV2 antagonist
|
HKC54 is a potent, selective TRPV2 antagonist with IC50 of 0.4 uM, 50-fold selectivity over TRPV1 and ∼70-fold selectivity over TRPA1. |
| PC-26401 |
RN-1665
TRPV4 antagonist
|
RN-1665 is a potent, selective and orally active TRPV4 antagonist with IC50 of 0.26 μM and 0.39 μM for hTRPV4 and rTRPV4, exhibits excellent selectivity for related TRP receptors such as TRPV1, TRPV3 and TRPM8. |
| PC-26099 |
DWP05195
TRPV1 antagonist
|
DWP05195 (DWP-05195) is a transient receptor potential vanilloid 1 (TRPV1) antagonist. |
| PC-26098 |
Vocacapsaicin hydrochloride
TRPV1 agonist
|
Vocacapsaicin hydrochloride (CA-008) is a non-opioid, water-soluble and injectable prodrug of capsaicin, a potent agonist of TRPV1 channel. |
| PC-25933 |
AV3-1
TRPV3 activator
|
AV3-1 (TRPV3 activator 1) is a specific small molecule TRPV3 activator with EC50 of 2.0 μM for mouse TRPV3 and 7.2 μM for human TRPV3. |
| PC-25855 |
Olvanil
TRPV1 agonist
|
Olvanil (NE-19550, N-Vanillyloleamide) is a potent, selective agonist of transient receptor potential vanilloid type 1 (TRPV1) channels with EC50 of 0.7 nM. |
| PC-25854 |
Capsiate
TRPV1 agonist
|
Capsiate is a non-pungent capsaicin analog and potent, selective TRPA1 agonist, evokes inward currents at -60 mV in the HEK293 cells expressing TRPV1with EC50 of 290 nM. |
| PC-25781 |
PPZ2
TRPC3/C6/C7 activator
|
PPZ2 is a selective activator of TRPC3/TRPC6/TRPC7, activates DAG-activated TRPC3/TRPC6/TRPC7 channels, promotes neurite outgrowth and neuronal survival via downstream Ca2+-dependent signals. |
| PC-25780 |
L687
TRPC3/C6/C7 activator
|
L687 is a potent, specific TRPC3/C6/C7 activator, induces cellular antisense oligonucleotide (ASO) uptake, also induces dextran uptake and increases endocytosis. |
| PC-25400 |
Br-cis-22a
TRPV6 inhibitor
|
Br-cis-22a is a brominated PCHPD analog of TRPV6 inhibitor cis-22a, inhibits uptake of Cd2+ into hTRPV6-expressing HEK 293 cells with IC50 of 0.96 uM. |
| PC-25399 |
TRPV6 inhibitor cis-22a TFA
TRPV6 inhibitor
|
TRPV6 inhibitor cis-22a TFA is a potent, selective inhibitor of TRPV6 calcium channel with IC50 of 0.32 uM, shows high selectivity against other calcium channels and related TRP targets, selectively reduces cancer cell growth on TRPV6 positive (T47D) breast cancer cells. |
