| Cat. No. |
Product Name |
Information |
| PC-25855 |
Olvanil
TRPV1 agonist
|
Olvanil (NE-19550, N-Vanillyloleamide) is a potent, selective agonist of transient receptor potential vanilloid type 1 (TRPV1) channels with EC50 of 0.7 nM. |
| PC-25854 |
Capsiate
TRPV1 agonist
|
Capsiate is a non-pungent capsaicin analog and potent, selective TRPA1 agonist, evokes inward currents at -60 mV in the HEK293 cells expressing TRPV1with EC50 of 290 nM. |
| PC-25781 |
PPZ2
TRPC3/C6/C7 activator
|
PPZ2 is a selective activator of TRPC3/TRPC6/TRPC7, activates DAG-activated TRPC3/TRPC6/TRPC7 channels, promotes neurite outgrowth and neuronal survival via downstream Ca2+-dependent signals. |
| PC-25780 |
L687
TRPC3/C6/C7 activator
|
L687 is a potent, specific TRPC3/C6/C7 activator, induces cellular antisense oligonucleotide (ASO) uptake, also induces dextran uptake and increases endocytosis. |
| PC-25400 |
Br-cis-22a
TRPV6 inhibitor
|
Br-cis-22a is a brominated PCHPD analog of TRPV6 inhibitor cis-22a, inhibits uptake of Cd2+ into hTRPV6-expressing HEK 293 cells with IC50 of 0.96 uM. |
| PC-25399 |
TRPV6 inhibitor cis-22a TFA
TRPV6 inhibitor
|
TRPV6 inhibitor cis-22a TFA is a potent, selective inhibitor of TRPV6 calcium channel with IC50 of 0.32 uM, shows high selectivity against other calcium channels and related TRP targets, selectively reduces cancer cell growth on TRPV6 positive (T47D) breast cancer cells. |
| PC-25398 |
TRPV6 inhibitor cis-22a
TRPV6 inhibitor
|
TRPV6 inhibitor cis-22a is a potent, selective inhibitor of TRPV6 calcium channel with IC50 of 0.32 uM, shows high selectivity against other calcium channels and related TRP targets, selectively reduces cancer cell growth on TRPV6 positive (T47D) breast cancer cells. |
| PC-25086 |
ML2-SA2
TRPML2 agonist
|
ML2-SA2 is a selective, small-molecule TRPML2 channel agonist with EC50 of 6.4 uM, while inhibiting TRPML1 and TRPML3 with IC50 of 2.3 uM and 15.9 uM, respectively. |
| PC-25031 |
Apecotrep
TRPC6 inhibitor
|
Apecotrep (TRPC6-IN-3) is a potent, orally active transient receptor potential C6 ion channel (TRPC6) inhibitor. |
| PC-24742 |
Resiniferatoxin
TRPV1 agonist
|
Resiniferatoxin ((+)-Resiniferatoxin) is a high affinity, selective agonist of transient receptor potential vanilloid 1 (TRPV1), binds HEK293/VR1 cells and CHO/VR1 cells with affinities of 84 and 103 pM, respectively. |
| PC-24333 |
TRPM8 antagonist 23
TRPM8 antagonist
|
TRPM8 antagonist 23 is a potent and selective TRPM8 antagonist with IC50 of 0.2 uM, 10-fold higher potency for human TRPM8 (hTRPM8) than for hTRPV1 and hTRPA1 channels. |
| PC-23886 |
TRPM4 inhibitor IBA
TRPM4 inhibitor
|
TRPM4 inhibitor IBA is a potent and selective inhibitor of the cation channel TRPM4 with IC50 of 142 nM. |
