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Cat. No. Product Name Information
PC-20478

Purinostat mesylate

Class I /IIb HDAC inhibitor

Purinostat mesylate is a potent, highly selective class I and IIb HDAC inhibitor with IC50 of 0.81, 1.4, 1.7, and 3.8 nM for class I HDAC1, 2, 3, and 8, and 11.5, 1.1 nM for class IIb HDAC 6 and 10, respectively.
PC-20402

SBI-46

HDAC inhibitor

SBI-46 (SBI 46) is an antiandrogen-equipped histone deacetylase (HDAC) inhibitor, strongly binds to androgen receptor (AR, IC50=8.4 nM) and potently inhibited HDACs and the proliferation of AR+ CRPC.
PC-20239

HO53

HDAC3 inhibitor

HO53 is a small moecule inducer of cathelicidin antimicrobial peptide gene (CAMP) expression in bronchial epithelium cells, HO53 is a histone deacetylase (HDAC) inhibitor, interacts directly with HDAC3.
PC-20238

RGFP963

HDAC3 inhibitor

RGFP963 (RGFP 963) is a potent, selective class I HDAC inhibitor with IC50 of 1.51 uM, 0.75 and 0.096 uM for HDAC1, HDAC2, and HDAC3, respectively.
PC-20237

RGFP966

HDAC3 inhibitor

RGFP966 (RGFP 966) is a potent, specific HDAC3 inhibitor with IC50 of 0.08 uM, without effective inhibition of any other HDACs at 15 uM.
PC-20197

TTA03-107

HDAC1 inhibitor

TTA03-107 is a potent, selective HDAC1 inhibitor with Ki of 3.22 and 17.6 nM for HDAC1/2, respectively.
PC-20141

HDAC10 inhibitor 10c

HDAC10 inhibitor

HDAC10 inhibitor 10c is a potent, selective HDAC10 inhibitor with IC50 of 20 nM, shows high specificity over HDAC6 and with no significant impact on class I HDACs.
PC-49844

NBM-T-L-BMX-OS01

HDAC8 inhibitor

NBM-T-L-BMX-OS01 (BMX, HDAC8 inhibitor) is a potent, selective and BB penetrant HDAC8 inhibitor with IC50 of 831 nM.
PC-49678

YSL-109

HDAC6 inhibitor

YSL-109 (YSL109) is a potent, highly selective small molecule inhibitor of HDAC6 with IC50 of 0.537 nM, >4000-fold selectivity over HDAC1 and HDAC8.
PC-49539

GH8HA01

HDAC8 inhibitor

GH8HA01 is a highly potent, selective HDAC8 inhibitor with Ki of 0.67 nM, highly selective against HDAC8 compared to other HDACs.
PC-49452

NN-429

HDAC6 inhibitor

NN-429 (NN429) is a potent, selective second-generation inhibitor of HDAC6 with IC50 of 3.2 nM, >312-fold selectivityt over all HDAC isoforms.
PC-49363

DKFZ-748

HDAC10 inhibitor

DKFZ-748 (DKFZ748) is a potent, specific HDAC10 inhibitor with cellular IC50 of 22 nM, >500-fold selectivity over other HDAC isozymes.

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