| Cat. No. |
Product Name |
Information |
| PC-62788 |
HDAC6-AR-IN-10
HDAC6/AR inhibitor
|
HDAC6-AR-IN-10 is a potent dual HDAC6/AR inhibitor with IC50 of 35.6 nM/<30 nM, shows weak inhibition on HDAC1/2/3 (IC50>1 uM). |
| PC-62704 |
Crebinostat
class I HDAC inhibitor
|
Crebinostat is a novel cognitive enhancer that inhibits class I HDAC/1/2/3 (IC50=0.7/1.0/2.0 nM), class IIb HDAC6 (IC50=9.3 nM) with weaker inhibition of the class I HDAC8 and no significant inhibition of the class IIa HDAC/4/5/7/9. |
| PC-62518 |
Corin
|
Corin is a dual action LSD1/HDAC inhibitor (IC50=0.33/0.20 uM) that potently targets the CoREST complex and shows more sustained inhibition of CoREST complex HDAC activity compared with entinostat. |
| PC-62467 |
BRD 8430
class I HDAC inhibitor
|
BRD 8430 is a potent, selective class I HDAC inhibitor (HDAC1>2 >3) with IC50 of 69 nM/560/1300 nM for HDAC1/2/3, respectively. |
| PC-62466 |
Apicidin
HDAC inhibitor
|
Apicidin (OSI 2040) is a fungal metabolite that exhibits potent, broad spectrum antiprotozoal activity in vitro, potently inhibits HDAC with IC50 of 0.7 nM in an enzyme activity assay. |
| PC-62465 |
BRD 8184
HDAC6 inhibitor
|
BRD 8184 is a potent, selective HDAC6 inhibitor with IC50 of 8 nM, weakly inhibits HDAC2 and HDAC8 (IC50=0.34 and 1.33 uM),has no activity for HDAC4 (IC50>30 uM).. |
| PC-62404 |
BRD4354
HDAC5/HDAC9 inhibitor
|
BRD4354 is a moderately potent, selective, reversible inhibitor of HDAC5 and HDAC9 with IC50 of 0.85 uM and 1.88 uM. |
| PC-62401 |
BRD3308
HDAC3 inhibitor
|
BRD3308 is a potent, selective HDAC3 inhibitor with IC50 of 54 nM, displays >20-fold selectivity over HDAC1 and HDAC2, >500-fold selectivity over other HDAC isoforms. |
| PC-62400 |
BRD2492
HDAC1/2 inhibitor
|
BRD2492 is a highly potent, selective HDAC1/2 inhibitor (IC50=2/19 nM, respectively) that displays excellent selectivity versus HDAC3 (IC50=2.08 uM, ≥110-fold selectivity) and all other HDAC isoforms, increases caspase-3 activation. |
| PC-62239 |
Pandacostat
pan-HDAC inhibitor
|
Pandacostat is the first nonselective HDAC inhibitor (pan-HDACi) with Ki of 0.12/0.07/0.95/0.18/0.032/1.1/0.5/1.4 uM for HDAC1/2/3/4/5/6/7/8/9, respectively. |
| PC-61957 |
OBP-801
|
OBP-801 (YM 753;Spiruchostatin A) is a novel cyclic-peptide-based HDAC inhibitor with IC50 of 2 nM. |
| PC-61915 |
HDAC1/2-IN-2
HDAC1/2 inhibitor
|
HDAC1/2-IN-2 is a potent, selective HDAC1 and HDAC2 inhibitor with IC50 of 6 nM and 45 nM, respectively. |
