| Cat. No. |
Product Name |
Information |
| PC-35281 |
Tianeptinostat
class I HDAC inhibitor
|
Tianeptinostat is a potent class I HDAC inhibitor with IC50 of 28, 33 and 51 nM for HDAC1, 2 and 3, respectively, also inhibits HDAC6 (IC50=1.6 nM) but not HDAC5 (IC50>80 uM). |
| PC-35280 |
Tianeptinaline
class I HDAC inhibitor
|
Tianeptinaline is a class I HDAC-selective, brain penetrant analogue of tianeptine with IC50 of 0.24, 0.12 and 0.155 uM for HDAC1, 2 and 3 respectively, does not inhibit HDAC6. |
| PC-35190 |
QTX125
HDAC6 inhibitor
|
QTX125 (QTX-125) is a novel potent, selective HDAC6 inhibitor, displays excellent selectivity over other HDACs. |
| PC-35170 |
FT895
HDAC11 inhibitor
|
FT895 (FT-895) is a potent and selective inhibitor of HDAC11 with IC50 of 3 nM, displays no significant activity against HDAC1-10 (IC50>5 uM). |
| PC-43492 |
Pracinostat
HDAC inhibitor
|
Pracinostat (SB939) is a potent, orally active HDAC inhibitor that potently inhibits class I, II, and IV HDACsw with Ki of 15-100 nM, inhibits HDAC1 with IC50 of 77 nM. |
| PC-63481 |
HDAC8-IN-22d
HDAC8 inhibitor
|
HDAC8-IN-22d is a potent, selective HDAC8 inhibitor with IC50 of 27.2 nM, exhibits no activity against other HDACs and limited activity against HDAC1 and 3. |
| PC-43451 |
Tubastatin A
HDAC6 inhibitor
|
Tubastatin A is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in cell-free assays. |
| PC-43450 |
Tubastatin A hydrochloride
HDAC6 inhibitor
|
Tubastatin A hydrochloride is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in cell-free assays. |
| PC-43447 |
Droxinostat
HDAC inhibitor
|
Droxinostat (NS-41080) is a selective HDAC inhibitor with IC50 of 16.9, 2.47 and 1.46 uM for HDAC3, HDAC6 and HDAC8, respectively. |
| PC-63389 |
GSK-3117391
HDAC inhibitor
|
GSK-3117391 (ESM-HDAC391, CHR-5154) is an orally active, myeloid-targeted histone deacetylase (HDAC) inhibitor with IC50 of 55 nM in a HeLa cell nuclear extract fluorometric assay, potently inhibits Class I, Class IIb and Class IV members (HDAC 1/2/3/8, HDAC6/10, and HDAC 11, respectively), with Class IIa enzymes (HDAC4/5/7/9) unaffected. |
| PC-63292 |
Marbostat-100
HDAC6 inhibitor
|
Marbostat-100 is a potent, selective HDAC6 inhibitor with Ki of 0.7 nM, displays >200-fold selectivity over HDAC1-5, and HDAC7-10. |
| PC-43291 |
NCH-51
HDAC inhibitor
|
NCH-51 is the S-isobutyryl prodrug of NCH-31, which is a potent HDAC inhibitor with IC50 of 48 nM for HDAC1, inhibits cell proliferation of NCI-H460 and MDA-MB-231 with IC50 of 2.1 and 4.4 uM. |
