| Cat. No. |
Product Name |
Information |
| PC-35436 |
Alteminostat
HDAC inhibitor
|
Alteminostat (CKD-581) is a novel histone deacetylase (HDAC) inhibitor, inhibits the class I-II HDAC family via histone H3 and tubulin acetylation. |
| PC-35369 |
SALL4 peptide FFW
SALL4-NURD inhibitor
|
SALL4 peptide FFW (RRKFAKFQWI, FFW peptide) is a potent therapeutic SALL4 peptide antagonist of SALL4-NURD (nucleosome remodeling deacetylase) interaction with target affinity of 23 nM. |
| PC-35363 |
ACY-957
HDAC1/2 inhibitor
|
ACY-957 (ACY957) is a potent, selective inhibitor of HDAC1 and HDAC2 with IC50 of 7 and 18 nM, shows limited activity against HDAC3 (IC50=1,300 nM) and no activity against HDAC4/5/6/7/8/9 (IC50>20 nM). |
| PC-35344 |
Tucidinostat
HDAC inhibitor
|
Tucidinostat (Chidamide, HBI-8000, CS055) is a novel histone deacetylase (HDAC) inhibitor with IC50 of 95/160/67/733/78/432 nM for HDAC1/2/3/8/10/11, respectively. |
| PC-35302 |
MPT0E028
HDAC inhibitor
|
Imofinostat (MPT0E028) is a potent HDAC inhibitor with IC50 of 53.0 nM, 106.2 nM, 29.5 nM for HDAC1, HDAC2 and HDAC6, respectively, inhibits nuclear HDAC activity with IC50 of 11.1 nM in HeLa cells, 9-30 times more potent than SAHA. |
| PC-35288 |
MPT0G211
HDAC6 inhibitor
|
MPT0G211 is a potent, selective HDAC6 inhibitor with IC50 of 0.291 nM, displays >1,000-fold selectivity over other HDAC isoforms. |
| PC-35281 |
Tianeptinostat
class I HDAC inhibitor
|
Tianeptinostat is a potent class I HDAC inhibitor with IC50 of 28, 33 and 51 nM for HDAC1, 2 and 3, respectively, also inhibits HDAC6 (IC50=1.6 nM) but not HDAC5 (IC50>80 uM). |
| PC-35280 |
Tianeptinaline
class I HDAC inhibitor
|
Tianeptinaline is a class I HDAC-selective, brain penetrant analogue of tianeptine with IC50 of 0.24, 0.12 and 0.155 uM for HDAC1, 2 and 3 respectively, does not inhibit HDAC6. |
| PC-35190 |
QTX125
HDAC6 inhibitor
|
QTX125 (QTX-125) is a novel potent, selective HDAC6 inhibitor, displays excellent selectivity over other HDACs. |
| PC-35170 |
FT895
HDAC11 inhibitor
|
FT895 (FT-895) is a potent and selective inhibitor of HDAC11 with IC50 of 3 nM, displays no significant activity against HDAC1-10 (IC50>5 uM). |
| PC-43492 |
Pracinostat
HDAC inhibitor
|
Pracinostat (SB939) is a potent, orally active HDAC inhibitor that potently inhibits class I, II, and IV HDACsw with Ki of 15-100 nM, inhibits HDAC1 with IC50 of 77 nM. |
| PC-63481 |
HDAC8-IN-22d
HDAC8 inhibitor
|
HDAC8-IN-22d is a potent, selective HDAC8 inhibitor with IC50 of 27.2 nM, exhibits no activity against other HDACs and limited activity against HDAC1 and 3. |
