| Cat. No. |
Product Name |
Information |
| PC-28356 |
CBHA
HDAC inhibitor
|
CBHA (m-Carboxycinnamic acid bishydroxamide) is a competitive and cell-permeable HDAC1 and HDAC3 inhibitor, cause accumulation of hyperacetylated histone H4 in cultured cells. |
| PC-28355 |
SBHA
HDAC inhibitor
|
SBHA (Suberoyl bis-hydroxamic acid) is a competitive and cell-permeable HDAC1 and HDAC3 inhibitor with ID50 values of 0.25 μM and 0.30 μM, respectively, renders MM cells susceptible to apoptosis and facilitates the mitochondrial apoptotic pathways. |
| PC-27750 |
BHC-13
HDAC8 inhibitor
|
BHC-13 is a potent, selective HDAC8 inhibitor. |
| PC-27749 |
BHC-10
HDAC8 inhibitor
|
BHC-10 is a potent, selective HDAC8 inhibitor. |
| PC-27747 |
HDAC8 inhibitor Compound 4
HDAC8 inhibitor
|
HDAC8 inhibitor Compound 4 is a potent and selective HDAC8 inhibitor with IC50 of 90 nM, weakly inhibit HDAC1, HDAC2, HDAC6 with IC50 of 1.7 uM, 3.9 uM and >50 uM. |
| PC-27700 |
MC2625
HDAC inhibitor
|
MC2625 is a potent histone deacetylase (HDAC) inhibitor, shows selective HDAC3 and HDAC6 inhibition with IC50 of 80 nM and 11 nM respectively, also potently reactivate HIV from latency with EC50 of 350 nM. |
| PC-27055 |
HDAC6 inhibitor 7b
HDAC6 inhibitor
|
HDAC6 inhibitor 7d is a potent, isoform-selective HDAC6 inhibitor with IC50 of 0.87 nM, shows >500- and >3000-fold selectivity over HDAC8 and HDAC1 respectively. |
| PC-27054 |
HDAC6 inhibitor 4d
HDAC6 inhibitor
|
HDAC6 inhibitor 4d (Nexturastat B) is a potent, isoform-selective HDAC6 inhibitor with IC50 of 1.6 nM, shows >500-fold selectivity over HDAC1. |
| PC-27053 |
HDAC6 inhibitor 4e
HDAC6 inhibitor
|
HDAC6 inhibitor 4e is a potent, isoform-selective HDAC6 inhibitor with IC50 of 1.7 nM, shows 355-fold selectivity over HDAC1. |
| PC-27052 |
HDAC6 inhibitor Compound 7b
HDAC6 inhibitor
|
HDAC6 inhibitor Compound 7b is a potent, selective HDAC6 inhibitor, inhibits proliferation, colony and spheroid formation as well as viability of prostate cancer cells, kills prostate cancer cells via HSP90α hyperacetylation-mediated androgen receptor protein downregulation. |
| PC-26984 |
BAS-2
HDAC6 inhibitor
|
BAS-2 is a potent, highly selective HDAC6 inhibitor with IC50 of 760 nM (hHDAC6). |
| PC-26983 |
(±)-trans-BAS-2
HDAC6 inhibitor
|
(±)-trans-BAS-2 is a potent, highly selective HDAC6 inhibitor with IC50 of 462 nM (hHDAC6), is more active than cis-BAS-2 (IC50=16.9 uM). |
