| Cat. No. |
Product Name |
Information |
| PC-42421 |
EDO-S101
HDAC inhibitor, DNA alkylator
|
EDO-S101 (Tinostamustine) is a fusion molecule comprising of the alkylator bendamustine and the HDAC-inhibitor vorinostat. |
| PC-42767 |
Abexinostat
HDAC inhibitor
|
PCI-24781 (Abexinostat, CRA 024781) is a broad spectrum HDAC inhibitor, inhibits pure recombinant HDAC1 with Ki of 7 nM. |
| PC-42126 |
HDACi-4b
HDAC inhibitor
|
A benzamide-type HDAC inhibitor with IC50 of 78 uM for changes of FXN mRNA in affected GM15850 cells. |
| PC-24898 |
TNI-97
HDAC6 inhibitor
|
TNI-97 is a potent, highly selective and orally bioavailable HDAC6 inhibitor with IC50 of 0.2 nM. |
| PC-24776 |
ITF3107
HDAC6 inhibitor
|
ITF3107 is a potent, selective HDAC6 inhibitor with IC50 of 5 nM, >70-fold more selective for HDAC6over HDAC1/2/3. |
| PC-24775 |
ACY-1083
HDAC6 inhibitor
|
ACY-1083 is a potent, selective and brain-penetrating HDAC6 inhibitor with IC50 of 3 nM, >250-fold more selective for HDAC6 than all other classes of HDAC isoforms. |
| PC-24774 |
ITF3985
HDAC6 inhibitor
|
ITF39856 (ITF-3985) is a potent, selective HDAC6 inhibitor with IC50 of 5 nM, >500-fold selective over HDAC1/2/3. |
| PC-24773 |
ITF3756
HDAC6 inhibitor
|
ITF3756 (ITF-3756) is a potent, selective HDAC6 inhibitor with IC50 of 17 nM, >80-fold selective versus HDAC8 and HDAC Class IIa isoforms (HDAC4, 5, 7, and 9). |
| PC-24769 |
Bavarostat
HDAC6 inhibitor
|
Bavarostat (EKZ-001) is a potent, selective HDAC6 inhibitor with IC50 of 60 nM, 16000-fold selectivity over HDAC1, HDAC2, and HDAC3. |
| PC-24736 |
WMJ-J-09
HDAC inhibitor
|
WMJ-J-09 a potent, hydroxamate based HDAC inhibitor, exhibits potent inhibitory activity against class I HDACs, including HDAC1 (IC50=7.5 nM), HDAC2 (IC50=21.3 nM), HDAC3 (IC50=18.4 nM), and HDAC8 (IC50=90.9 nM), also strongly inhibitsHDAC6 (class IIb) with IC50 of 3.9 nM. |
| PC-24698 |
PAT-1102
HDAC inhibitor
|
PAT-1102 (FNDR-20123) is a novel, potent, orally available HDAC inhibitor with IC50 of 3 nM in cell-free HDAC enzymatic assays, also inhibits Plasmodium HDAC with IC50 of 31 nM. |
| PC-24619 |
Bisthianostat
HDAC inhibitor
|
Bisthianostat (CF367) is an orally bioavailable pan-inhibitor of human histone deacetylase (HDAC) with IC50 of 0.07, 0.26 and 0.79 uM for HDAC1, HDAC2 and HDAC6 respectively. |
