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Cat. No. Product Name Information
PC-24228

HDAC6 inhibitor DR-3

HDAC6 inhibitor

HDAC6 inhibitor DR-3 is a selective small molecule HDAC6 inhibitor with IC50 of 78.1 nM, shows 100-fold selectivity over HDAC1.
PC-24027

SR-4370

HDAC inhibitor

SR-4370 is a novel HDAC inhibitor with IC50 of 0.13/0.5/0.006/3.4/2.3 μM for HDAC1/2/3/6/8, respectively, also is a latency-reversing agent (LRA) for reactivation of latent HIV-1.
PC-24022

HDAC11 inhibitor B6

HDAC11 inhibitor

HDAC11 inhibitor B6 is a potent, highly selective HDAC11 inhibitor with IC50 of 51.1 nM, >90-fold selective over HDAC8 and shows no activity against all other HDAC subtypes.
PC-23991

IHCH9033

class I HDAC inhibitor

IHCH9033 is a selective, triazole-containing class I HDAC inhibitor, exhibits an increased antitumor effect in FLT3-ITD AML through effectively eliminating leukemia burden and overcoming resistance to FLT3i.
PC-23970

RG2833

HDAC1/3 inhibitor

RG2833 is a potent, orally bioavailable, brain-penetrant histone deacetylase HDAC1/3 inhibitor with IC50 of 60/50 mM respectively.
PC-23965

HDAC3 inhibitor LSQ-28

HDAC3 inhibitor

LSQ-28 is a potent, selective HDAC3 inhibitor with IC50 of 42 nM, >150-fold selective over HDAC1, HDAC2, and HDAC6.
PC-23806

NSC3852

HDAC inhibitor

NSC3852 is a small molecule inhibitor of histone deacetylase (HDAC) with cell differentiation and antiproliferative activity in human breast cancer cells, synergistically enhances the cytotoxicity of olaparib in oral squamous cell carcinoma.
PC-23423

HDAC6 inhibitor OXHA

HDAC6 inhibitor

OXHA is a potent selective HDAC6 inhibitor with IC50 of 3.7 nM, promotes the acetylation of α-tubulin, >40-fold selectivity over HDAC1/2/3/8.
PC-23348

PB131

HDAC6 inhibitor

PB131 is a potent, selective and brain-permeable HDAC6 inhibitor with IC50 of 1.8 nM, <100-fold selective over other HDAC isoforms.
PC-22845

HQ-30

HDAC3 inhibitor, PD-L1 degrader

HQ-30 is a potent, dual-acting HDAC3 inhibitor (IC50=89 nM) and PD-L1 degrader (DC50=5.7 uM, Dmax=80% at 10 uM).
PC-22801

HDAC6 inhibitor 5a

HDAC6 inhibitor

HDAC6 inhibitor 5a (MPI-5a) is potent and selective HDAC6 inhibitor with IC50 of 36 nM, >50-fold selectivity over other HDACs
PC-22782

Leuxinostat

HDAC6 inhibitor

Leuxinostat is a potent, specific HDAC6 inhibitor with IC50 of 30 nM, induces apoptosis in FLT3-ITD AML cells.

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