| Cat. No. |
Product Name |
Information |
| PC-22259 |
QAPHA
Tubulin/HDAC6 inhibitor
|
QAPHA is a dual function small molecule as both a tubulin polymerization and HDAC inhibitor, induces immunogenic cell death (ICD) through HDAC6 inhibition. |
| PC-22104 |
STR-V-53
HDAC inhibitor
|
STR-V-53 is a novel glycosylated, liver cancer-selective histone deacetylase (HDAC) inhibitor with IC50 of 24.3/60.1/213.43 nM for HDAC1/2/3/6, demonstrates exquisite selective cytotoxicity against human HCC cells. |
| PC-21991 |
DNMT/HDACi 15a
DNMT/HDAC inhibitor
|
DNMT/HDACi 15a is a potent, dual DNMT and HDAC inhibitor with IC50 of 57, 17 nM for HDAC1, HDAC6 respectively. |
| PC-21870 |
SP-2-225
HDAC6 inhibitor
|
SP-2-225 is a potent, selective HDAC6 inhibitor, improves antitumor immune responses and prevent tumor relapse after radiotherapy. |
| PC-21844 |
RBC1HI
HDAC1/2 inhibitor
|
RBC1HI is a novel small molecule HDAC1/HDAC2 inhibitor, attenuates behavioral manifestations of oxycodone withdrawal, especially in mice with neuropathic pain. |
| PC-21650 |
Tefinostat
HDAC inhibitor
|
Tefinostat (CHR-2845) is a monocyte/macrophage targeted pan histone deacetylase (HDAC) inhibitor, which is cleaved into the active acid CHR-2847 by the intracellular esterase human carboxylesterase-1 (hCE-1). |
| PC-21608 |
CM-444
HDAC inhibitor
|
CM-444 is a potent histone deacetylase (HDAC) inhibitor with IC50 of 7/51/18/531 nM for HDAC1/2/3/6 respectively, also inhibits DNMT1 with IC50 of 2160 nM. |
| PC-21607 |
CM-1758
HDAC inhibitor
|
CM-1758 is a novel histone deacetylase (HDAC) inhibitor with IC50 of 5 nM and 126 nM for HDAC1 and HDAC6, respectively. |
| PC-21537 |
HR488B
HDAC1 inhibitor
|
HR488B is a potent, selective HDAC1 inhibitor with IC50 of 1.24 uM, effectively inhibits the proliferation of CRC cells. |
| PC-21520 |
YSR734
HDAC inhibitor
|
YSR734 is a first-in-class covalent HDACs inhibitor with IC50 of 0.109 uM, 0.154 uM and 0.143 uM for HDAC1, HDAC2, and HDAC3, sparing other deacetylases (HDAC4-HDAC10, IC50>10 uM). |
| PC-21412 |
Quisinostat
HDAC inhibitor
|
Quisinostat (JNJ-26481585) is potent, second-generation histone deacetylase (HDAC) inhibitor with IC50 of 0.11 nM-0.64 nM for HDAC1, HDAC2, HDAC4, HDAC10 and HDAC11. |
| PC-21403 |
HDAC11 inhibitor PB94
HDAC11 inhibitor
|
HDAC11 inhibitor PB94 is a potent, selective and brain-permeable HDAC11 inhibitor with IC50 of 108 nM, >40-fold over other HDAC isoforms. |
