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Cat. No. Product Name Information
PC-49678

YSL-109

HDAC6 inhibitor

YSL-109 (YSL109) is a potent, highly selective small molecule inhibitor of HDAC6 with IC50 of 0.537 nM, >4000-fold selectivity over HDAC1 and HDAC8.
PC-49539

GH8HA01

HDAC8 inhibitor

GH8HA01 is a highly potent, selective HDAC8 inhibitor with Ki of 0.67 nM, highly selective against HDAC8 compared to other HDACs.
PC-49452

NN-429

HDAC6 inhibitor

NN-429 (NN429) is a potent, selective second-generation inhibitor of HDAC6 with IC50 of 3.2 nM, >312-fold selectivityt over all HDAC isoforms.
PC-49363

DKFZ-748

HDAC10 inhibitor

DKFZ-748 (DKFZ748) is a potent, specific HDAC10 inhibitor with cellular IC50 of 22 nM, >500-fold selectivity over other HDAC isozymes.
PC-38799

NQN-1

HDAC6 inhibitor

NQN-1 is a highly selective, small molecule HDAC6 inhibitor with IC50 of 5.54 uM and Ki of 1.30 uM.
PC-38796

A452

HDAC6 inhibitor

A452 is a potent and selective HDAC6 inhibitor, effectively inhibits the cell growth and viability of various cancer cell types, irrespective of p53 status.
PC-73237

UBD253

HDAC6-ISG15 inhibitor

UBD253 (SGC-UBD253) is a potent, selective ubiquitin chemical probe for ubiquitin binding domain of HDAC6 with Kd of 84 nM (SPR), inhibits the HDAC6-ISG15 interaction (EC50=1.9 uM, nanoBRET).
PC-73193

Rocilinostat

HDAC6 inhibitor

Ricolinostat (ACY-1215) is a potent and selective HDAC6 inhibitor with IC50 of 5 nM.
PC-72875

MJM-1

HDAC inhibitor

MJM-1 is a small-molecule brain-penetrant HDAC inhibitor that increases the overall level of histone 3 (H3) acetylation in prostate cancer cell line.
PC-72740

NN-390

HDAC6 inhibitor.

NN-390 (NN390) is a potent, selective HDAC6 inhibitor with IC50 of 9.8 nM, >200-550-fold selectivity over other HDAC isoforms.
PC-72344

SW-101

HDAC6 inhibitor

SW-101 (SW101) is a potent, selective HDAC6 inhibitor with IC50 of 0.7 nM, >200-fold selectivity over HDAC1/2/3.
PC-72343

HDAC3 inhibitor PT3

HDAC3 inhibitor

HDAC3 inhibitor PT3 is a novel potent, selective, BBB-permeable HDAC3 inhibitor.

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