| Cat. No. |
Product Name |
Information |
| PC-62467 |
BRD 8430
class I HDAC inhibitor
|
BRD 8430 is a potent, selective class I HDAC inhibitor (HDAC1>2 >3) with IC50 of 69 nM/560/1300 nM for HDAC1/2/3, respectively. |
| PC-62466 |
Apicidin
HDAC inhibitor
|
Apicidin (OSI 2040) is a fungal metabolite that exhibits potent, broad spectrum antiprotozoal activity in vitro, potently inhibits HDAC with IC50 of 0.7 nM in an enzyme activity assay. |
| PC-62465 |
BRD 8184
HDAC6 inhibitor
|
BRD 8184 is a potent, selective HDAC6 inhibitor with IC50 of 8 nM, weakly inhibits HDAC2 and HDAC8 (IC50=0.34 and 1.33 uM),has no activity for HDAC4 (IC50>30 uM).. |
| PC-62404 |
BRD4354
HDAC5/HDAC9 inhibitor
|
BRD4354 is a moderately potent, selective, reversible inhibitor of HDAC5 and HDAC9 with IC50 of 0.85 uM and 1.88 uM. |
| PC-62401 |
BRD3308
HDAC3 inhibitor
|
BRD3308 is a potent, selective HDAC3 inhibitor with IC50 of 54 nM, displays >20-fold selectivity over HDAC1 and HDAC2, >500-fold selectivity over other HDAC isoforms. |
| PC-62400 |
BRD2492
HDAC1/2 inhibitor
|
BRD2492 is a highly potent, selective HDAC1/2 inhibitor (IC50=2/19 nM, respectively) that displays excellent selectivity versus HDAC3 (IC50=2.08 uM, ≥110-fold selectivity) and all other HDAC isoforms, increases caspase-3 activation. |
| PC-62239 |
Pandacostat
pan-HDAC inhibitor
|
Pandacostat is the first nonselective HDAC inhibitor (pan-HDACi) with Ki of 0.12/0.07/0.95/0.18/0.032/1.1/0.5/1.4 uM for HDAC1/2/3/4/5/6/7/8/9, respectively. |
| PC-61957 |
OBP-801
|
OBP-801 (YM 753;Spiruchostatin A) is a novel cyclic-peptide-based HDAC inhibitor with IC50 of 2 nM. |
| PC-61915 |
HDAC1/2-IN-2
HDAC1/2 inhibitor
|
HDAC1/2-IN-2 is a potent, selective HDAC1 and HDAC2 inhibitor with IC50 of 6 nM and 45 nM, respectively. |
| PC-70244 |
CGK1026
HDAC inhibitor
|
CGK1026 is a small molecule that inhibits human telomerase reverse transcriptase (hTERT) expression, inhibits HDAC activity with IC50 of 100 nM. |
| PC-70352 |
LB-205
HDAC inhibitor
|
LB-205 is a Zn2+-dependent pan-inhibitor of class I and class II HDACs with a long half-life (12h) in vivo. |
| PC-70299 |
WT161
HDAC6 inhibitor
|
WT161 (WT-161) is a potent, selective, and bioavailable HDAC6 inhibitor with IC50 0.4 nM. |
