| Cat. No. |
Product Name |
Information |
| PC-60293 |
TMP195
class IIa HDAC inhibitor
|
TMP-195 is a first-in-class, potent, selective class IIa HDACs (HDAC4, HDAC5, HDAC7 and HDAC9) inhibtior with IC50 of 60, 59, 26, and 15 nM, respectively. |
| PC-60136 |
SB-429201
HDAC1 inhibitor
|
SB-429201 is a potent, selective HDAC1 inhibitor with IC50 of 1.5 uM, increases histone acetylation in SW620 cells. |
| PC-60135 |
SB-379278A
HDAC8 inhibitor
|
SB-379278A is potent and selective HDAC8 inhibitor with IC50 of 0.5 uM. |
| PC-60134 |
NCC-149
HDAC8 inhibitor
|
NCC-149 is a potent and selective HDAC8 inhibitor with IC50 of 70 nM. |
| PC-60133 |
HDAC8-IN-20a
HDAC8 inhibitor
|
HDAC8-IN-20a is a potent and selective HDAC8 inhibitor with IC50 of 27 nM. |
| PC-45534 |
BRD-73954
HDAC6/HDAC8 inhibitor
|
BRD-73954 is the first potent, selective HDAC6/8 dual inhibitor with IC50s of 36/120 nM. |
| PC-42638 |
Tasquinimod
HDAC4 inhibitor, S100A9 inhibitor
|
An orally active antiangiogenic agent with anti-prostate cancer activity, an allosteric modulator of HDAC4 with Kd of 10-30 nM. |
| PC-42903 |
Mocetinostat
class I HDAC inhibitor
|
Mocetinostat (MGCD0103) is an isotype-selective small molecule class I HDAC inhibitor with IC50 of 0.15/0.29/1.66 uM for HDAC1/2/3. |
| PC-42181 |
ITSA-1
HDAC activator
|
ITSA-1 is a small molecule histone deacetylase (HDAC) activator that counteracts trichostatin A (TSA)-induced cell cycle arrest, histone acetylation and transcriptional activation. |
| PC-45618 |
Pimelic Diphenylamide 106
class I HDAC inhibitor
|
Pimelic Diphenylamide 106 (RGFA-8; TC-H 106; BRD4657) is a slow, tight-binding inhibitor of class I HDACs (HDAC1/2/3, Ki=148/102/14 nM respectively). |
| PC-45595 |
LMK-235
HDAC4/5 inhibitor
|
LMK-235 (LMK235) is a selective HDAC5 and HDAC4 inhibitor with IC50 of 4.22 nM and 11.9 nM respectively. |
| PC-45907 |
CI-994
class I HDAC inhibitor
|
CI-994 (Tacedinaline) is a potent, selective class I HDAC inhibitor with IC50 of 0.9/0.9/1.2 uM for HDAC1/2/3, respectively. |
