| Cat. No. |
Product Name |
Information |
| PC-72098 |
AES-135
HDAC inhibitor
|
AES-135 (AES135) is a novel small molecule HDAC inhibitor, inhibits HDAC3, HDAC6, HDAC11 with IC50 of 654, 190, 636 nM, with low-uM activity against HDAC8 (IC50=1.2 uM). |
| PC-72097 |
SIS17
HDAC11 inhibitor
|
SIS17 is a selective, cell-active HDAC11 inhibitor with IC50 of 0.83 uM. |
| PC-72096 |
FT108
HDAC6 inhibitor
|
FT108 (FT-108) is a potent, selective HDAC6 inhibitor (IC50=26 nM) relative to other HDAC family members (HDAC3 IC50=6.68 uM and HDAC8 IC50=4.07 uM). |
| PC-72095 |
FT234
HDAC11 inhibitor
|
FT234 (FT-234) is a selective HDAC11 inhibitor. |
| PC-72094 |
Elevenostat
HDAC11 inhibitor
|
Elevenostat (JB3-22) is a selective HDAC11 inhibitor with IC50 of 0.235 uM. |
| PC-72093 |
SS-208
HDAC6 inhibitor
|
SS-208 (SS208, AVS100) is a novel potent, selective inhibitor of histone deacetylase 6 (HDAC6) with IC50 of 12 nM, >100-fold selectivity over HDAC1/4/5/7/8/9/11. |
| PC-72091 |
NR-160
HDAC6 inhibitor
|
NR-160 (NR160) is a novel potent, selective inhibitor of histone deacetylase 6 (HDAC6) with IC50 of 30 nM, shows SI (75-1847 )over all HDAC class I isoforms. |
| PC-72090 |
Suprastat
HDAC6 inhibitor
|
Suprastat is a novel potent, selective inhibitor of histone deacetylase 6 (HDAC6) with IC50 of 0.9 nM. |
| PC-72089 |
PTG-0861
HDAC6 inhibitor
|
PTG-0861 (JG-265) is a novel potent, selective HDAC6 inhibitor with IC50 of 5.92 nM, >36-fold selectivity over other HDACs. |
| PC-38242 |
DSK638
RECK inducer
|
DSK638 (DSK-638) is a potent small moelcule RECK inducer, binds histone deacetylases (HDACs) with IC50 of 5-10 uM for HDAC1/3. |
| PC-38119 |
LSH-A54
class I HDAC inhibitor
|
LSH-A54 is a potent, class I selective HDAC inhibitor with IC50 of 26.2 nM (HDAC1) and 59.3 nM (HDAC2). |
| PC-36094 |
CHR-3996
class I HDAC inhibitor
|
CHR-3996 (Nanatinostat, VRx-3996, CHR3996, Tractinostat) is a potent, class I-selective, orally active HDAC inhibitor with IC50 of 3-7 nM for HDAC1/2/3. |
