| Cat. No. |
Product Name |
Information |
| PC-72090 |
Suprastat
HDAC6 inhibitor
|
Suprastat is a novel potent, selective inhibitor of histone deacetylase 6 (HDAC6) with IC50 of 0.9 nM. |
| PC-72089 |
PTG-0861
HDAC6 inhibitor
|
PTG-0861 (JG-265) is a novel potent, selective HDAC6 inhibitor with IC50 of 5.92 nM, >36-fold selectivity over other HDACs. |
| PC-38242 |
DSK638
RECK inducer
|
DSK638 (DSK-638) is a potent small moelcule RECK inducer, binds histone deacetylases (HDACs) with IC50 of 5-10 uM for HDAC1/3. |
| PC-38119 |
LSH-A54
class I HDAC inhibitor
|
LSH-A54 is a potent, class I selective HDAC inhibitor with IC50 of 26.2 nM (HDAC1) and 59.3 nM (HDAC2). |
| PC-36094 |
CHR-3996
class I HDAC inhibitor
|
CHR-3996 (Nanatinostat, VRx-3996, CHR3996, Tractinostat) is a potent, class I-selective, orally active HDAC inhibitor with IC50 of 3-7 nM for HDAC1/2/3. |
| PC-35932 |
SW-100
HDAC6 inhibitor
|
SW-100 (SW100) is a potent, selective, brain penetrable HDAC6 inhibitor with IC50 of 2.3 nM, displays >1,000-fold selectivity over all other class I, II, and IV HDAC isoforms. |
| PC-35926 |
CM-675
PDE5/HDAC inhibitor
|
CM-675 (CM675) is a potent, dual PDE5 and classI-HDAC inhibitor with IC50 of 114/673 nM for PDE5A/HDAC1, respectively. |
| PC-35827 |
CHDI-390576
class IIa HDAC inhibitor
|
CHDI-390576 (CHDI390576) is a potent, cell permeable and CNS penetrant class IIa HDAC inhibitor with IC50 of 54/60/31/50 nM for HDAC4/5/7/9, respectively. |
| PC-35757 |
RTS-V5
HDAC-proteasome inhibitor
|
RTS-V5 (Dual HDAC-proteasome inhibitor RTS-V5) is the first-in-class, dual HDAC-proteasome inhibitor with IC50 of 0.27 uM (HDAC6), inhibits HDAC8 (IC50=0.53 uM), and low activity against HDAC/1/2/3. |
| PC-35666 |
Class I and IIB HDAC inhibitor 42
Class I/IIB HDAC inhibitor
|
Class I and IIB HDAC inhibitor 42 is a novel potent, selective class I and IIB inhibitor (HDAC1 Ki=0.27 nM) for topical treatment of cutaneous t-cell lymphoma. |
| PC-43533 |
Tubacin
HDAC6 inhibitor
|
Tubacin is a potent, selective inhibitor of class II histone deacetylase 6 (HDAC6) with IC50 of 4 nM, displays> 300-fold selectivity against all other HDAC isoforms. |
| PC-35436 |
Alteminostat
HDAC inhibitor
|
Alteminostat (CKD-581) is a novel histone deacetylase (HDAC) inhibitor, inhibits the class I-II HDAC family via histone H3 and tubulin acetylation. |
