| Cat. No. |
Product Name |
Information |
| PC-35932 |
SW-100
HDAC6 inhibitor
|
SW-100 (SW100) is a potent, selective, brain penetrable HDAC6 inhibitor with IC50 of 2.3 nM, displays >1,000-fold selectivity over all other class I, II, and IV HDAC isoforms. |
| PC-35926 |
CM-675
PDE5/HDAC inhibitor
|
CM-675 (CM675) is a potent, dual PDE5 and classI-HDAC inhibitor with IC50 of 114/673 nM for PDE5A/HDAC1, respectively. |
| PC-35827 |
CHDI-390576
class IIa HDAC inhibitor
|
CHDI-390576 (CHDI390576) is a potent, cell permeable and CNS penetrant class IIa HDAC inhibitor with IC50 of 54/60/31/50 nM for HDAC4/5/7/9, respectively. |
| PC-35757 |
RTS-V5
HDAC-proteasome inhibitor
|
RTS-V5 (Dual HDAC-proteasome inhibitor RTS-V5) is the first-in-class, dual HDAC-proteasome inhibitor with IC50 of 0.27 uM (HDAC6), inhibits HDAC8 (IC50=0.53 uM), and low activity against HDAC/1/2/3. |
| PC-35666 |
Class I and IIB HDAC inhibitor 42
Class I/IIB HDAC inhibitor
|
Class I and IIB HDAC inhibitor 42 is a novel potent, selective class I and IIB inhibitor (HDAC1 Ki=0.27 nM) for topical treatment of cutaneous t-cell lymphoma. |
| PC-43533 |
Tubacin
HDAC6 inhibitor
|
Tubacin is a potent, selective inhibitor of class II histone deacetylase 6 (HDAC6) with IC50 of 4 nM, displays> 300-fold selectivity against all other HDAC isoforms. |
| PC-35436 |
Alteminostat
HDAC inhibitor
|
Alteminostat (CKD-581) is a novel histone deacetylase (HDAC) inhibitor, inhibits the class I-II HDAC family via histone H3 and tubulin acetylation. |
| PC-35369 |
SALL4 peptide FFW
SALL4-NURD inhibitor
|
SALL4 peptide FFW (RRKFAKFQWI, FFW peptide) is a potent therapeutic SALL4 peptide antagonist of SALL4-NURD (nucleosome remodeling deacetylase) interaction with target affinity of 23 nM. |
| PC-35363 |
ACY-957
HDAC1/2 inhibitor
|
ACY-957 (ACY957) is a potent, selective inhibitor of HDAC1 and HDAC2 with IC50 of 7 and 18 nM, shows limited activity against HDAC3 (IC50=1,300 nM) and no activity against HDAC4/5/6/7/8/9 (IC50>20 nM). |
| PC-35344 |
Tucidinostat
HDAC inhibitor
|
Tucidinostat (Chidamide, HBI-8000, CS055) is a novel histone deacetylase (HDAC) inhibitor with IC50 of 95/160/67/733/78/432 nM for HDAC1/2/3/8/10/11, respectively. |
| PC-35302 |
MPT0E028
HDAC inhibitor
|
MPT0E028 (MPT 0E028) is a potent HDAC inhibitor that inhibits nuclear HDAC activity with IC50 of 11.1 nM in HeLa cells, 9-30 times more potent than SAHA. |
| PC-35288 |
MPT0G211
HDAC6 inhibitor
|
MPT0G211 is a potent, selective HDAC6 inhibitor with IC50 of 0.291 nM, displays >1,000-fold selectivity over other HDAC isoforms. |
