| Cat. No. |
Product Name |
Information |
| PC-45089 |
MC1568
class IIa HDAC inhibitor
|
MC1568 is a potent and selective class IIa HDAC inhibitor with IC50 of 220 nM for maize HD1-A. |
| PC-42902 |
Entinostat
class I HDAC inhibitor
|
Entinostat (MS275) is a potent and selective class I HDACs inhibitor with IC50 of 243/453/248 nM for HDAC1/2/3. |
| PC-45619 |
BML-210
HDAC inhibitor
|
BML-210 is a small molecule histone deacetylase (HDAC) inhibitor that induces Ac-histone in A549 cells with EC50 of 181 uM. |
| PC-42249 |
CXD101
class I HDAC inhibitor
|
Zabadinostat (CXD101) is a potent, selective and orally active class I HDAC inhibitor with IC50s of 63 nM, 570 nM and 550 nM for HDAC1, HDAC2 and HDAC3, respectively, has no activity against class II HDACs. |
| PC-42671 |
Valproic acid sodium salt
HDAC inhibitor
|
Valproic acid sodium salt is a HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2. |
| PC-42670 |
Valproic acid
HDAC inhibitor
|
Valproic acid is a HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2. |
| PC-42421 |
EDO-S101
HDAC inhibitor
|
EDO-S101 (Tinostamustine) is a fusion molecule comprising of the alkylator bendamustine and the HDAC-inhibitor vorinostat. |
| PC-42767 |
PCI-24781
HDAC inhibitor
|
PCI-24781 (Abexinostat, CRA 024781) is a broad spectrum HDAC inhibitor, inhibits pure recombinant HDAC1 with Ki of 7 nM. |
| PC-42126 |
HDACi-4b
HDAC inhibitor
|
A benzamide-type HDAC inhibitor with IC50 of 78 uM for changes of FXN mRNA in affected GM15850 cells. |
| PC-24425 |
DDI199
HDAC/ChE/MAO inhibitor
|
DDI199 (Contilistat) is a novel multi-target molecule by linking Contilisant and Vorinostat (SAHA), inhibits histone deacetylases (HDACs), monoamine oxidases (MAOs) and cholinesterases (ChEs), and modulate histamine H3 (H3R) and Sigma 1 Receptor (S1R) receptors, shows anti-tumor activity against glioma stem cells (GSCs). |
| PC-24323 |
Trichostatin A
HDAC inhibitor
|
Trichostatin A (TSA) is a potent and specific, irreversible inhibitor of class I/II HDACs with IC50 of 1.8 nM for HDAC. |
| PC-24229 |
HDAC6 inhibitor FDR2
HDAC6 inhibitor
|
HDAC6 inhibitor FDR2 is a selective small molecule HDAC6 inhibitor with IC50 of 50.8 nM, shows >100-fold selectivity over HDAC1. |
