| Cat. No. |
Product Name |
Information |
| PC-61915 |
HDAC1,2-IN-2
|
A potent, selective HDAC1 and HDAC2 inhibitor with IC50 of 6 nM and 45 nM, respectively. |
| PC-70244 |
CGK-1026
|
A small molecule that inhibits human telomerase reverse transcriptase (hTERT) expression. |
| PC-70352 |
LB-205
|
A Zn2+-dependent pan-inhibitor of class I and class II HDACs with a long half-life (12h) in vivo. |
| PC-60830 |
HDAC6 inhibitor NCT-14b
|
A potent, selective HDAC6 inhibitor with IC50 of 84 nM, with IC50s of >3.5 uM for the other HDAC isoforms.. |
| PC-60828 |
T326
|
A potent and selective HDAC3 inhibitor with IC50 of 0.26 uM, with no activity against HDAC1/4/6/8. |
| PC-60827 |
T247
|
A potent and selective HDAC3 inhibitor with IC50 of 0.24 uM, >75-fold selectivity over HDAC1 and no activity against HDAC4/6/8. |
| PC-60692 |
BML-281
|
A potent, selective HDAC6 inhibitor with IC50 of 0.002 nM, weakly inhibits HDAC3 (IC50=0.42 nM) and >50,000-fold selectivity over HDAC1/2/8/10. |
| PC-70234 |
Splitomicin
|
A selecitve small molecule inhibitor of Sir2p histone deacetylase, displaying higher activity in vivo (minimal inhibitory concentration= 0.49 uM) than in vitro (IC50=60 uM). |
| PC-70233 |
SK-7041
|
A potent HDAC inhibitor with IC50 of 172 nM. |
| PC-60415 |
cis CM-414
|
A first-in-class, dual inhibitor of PDE5 and HDAC that inhibits HDAC1/2/3/6 (IC50=310/490/322/91 nM, respectively) and PDE5 (IC50=60 nM). |
| PC-60136 |
SB-429201
|
A potent, selective HDAC1 inhibitor with IC50 of 1.5 uM. |
| PC-60135 |
SB-379278A
|
A potent and selective HDAC8 inhibitor with IC50 of 0.5 uM.. |
