| Cat. No. |
Product Name |
Information |
| PC-21394 |
PB118
HDAC6 inhibitor.
|
PB118 is a potent, selective HDAC6 inhibitor with IC50 of 5.6 nM, shows >1000 times selectively towards HDAC1, reduces alzheimer's disease neuropathology. |
| PC-21309 |
KPZ560
HDAC1/2 inhibitor
|
KPZ560 is a potent, HDAC1/2-selective inhibitor with IC50 of 12/68 nM, respectively. |
| PC-21304 |
Mz325
Sirt2/HDAC6 inhibitor
|
Mz325 is a potent, selective, dual inhibitor of Sirt2/HDAC6 with IC50 of 320/43 nM, respectively. |
| PC-21042 |
KD5170
Class I /II HDAC inhibitor
|
KD5170 (KD-5170) is a potent mercaptoketone-based Class I and II-histone deacetylase (HDAC) inhibitor with IC50 of 45 nM in HeLa cell-based histone H3 hyperacetylation assay. |
| PC-20671 |
TNG260
CoreDAC inhibitor
|
TNG260 (TNG-260) is a potent, CoREST-selective deacetylase (CoreDAC) inhibitor, inhibits HDAC1 with 10-fold selectivity over HDAC3 in cells. |
| PC-20478 |
Purinostat mesylate
Class I /IIb HDAC inhibitor
|
Purinostat mesylate is a potent, highly selective class I and IIb HDAC inhibitor with IC50 of 0.81, 1.4, 1.7, and 3.8 nM for class I HDAC1, 2, 3, and 8, and 11.5, 1.1 nM for class IIb HDAC 6 and 10, respectively. |
| PC-72740 |
NN-390
HDAC6 inhibitor.
|
NN-390 (NN390) is a potent, selective HDAC6 inhibitor with IC50 of 9.8 nM, >200-550-fold selectivity over other HDAC isoforms. |
