| Cat. No. |
Product Name |
Information |
| PC-20695 |
NYX-2925
NMDAR PAM
|
NYX-2925 (NYX2925) is a potent, specific NMDAR positive allosteric-modulator, facilitates [3H] MK-801 binding in all four human NMDAR2 subtypes with EC50 of 55 pM, 28 fM, 11 pM, and 55 pM for hNR2A, 2B, 2C, and 2D receptors, respectively. |
| PC-20090 |
BPAM344
GluK2 PAM
|
BPAM344 (BPAM-344) is a positive allosteric modulator of GluK2 kainate receptor, potentiates glutamate-evoked currents of GluK2a 21-fold at 200 uM (EC50=79 uM). |
| PC-38728 |
WMS-1410
NR2B receptor antagonist
|
WMS-1410 is a NR2B selective NMDA receptor antagonist with Ki value of 14 nM, antagonizes glutamate induced excitotoxicity with IC50 of 18.4 nM. |
| PC-38673 |
Plazinemdor
NMDA PAM
|
Plazinemdor (CAD-9303) is a potent N-methyl-D-aspartate (NMDA) receptor positive allosteric modulator with potential for schizophrenia. |
| PC-73433 |
Onfasprodil
NMDA antagonist
|
Onfasprodil is a potent, selective N-methyl-D-aspartate (NMDA) receptor antagonist. |
| PC-43363 |
SDZ 220-581 hydrochloride
|
SDZ 220-581 is a potent, competitive NMDA receptor antagonist with pKi of 7.7, fully protects against maximal electroshock seizures (MES) at oral doses of 10 mg/kg in rats and in mice. . |
| PC-43362 |
SDZ 220-581 ammonium salt
|
SDZ 220-581 is a potent, competitive NMDA receptor antagonist with pKi of 7.7, fully protects against maximal electroshock seizures (MES) at oral doses of 10 mg/kg in rats and in mice. . |
| PC-43280 |
Ifenprodil tartrate
|
Ifenprodil tartrate is a NMDA receptor antagonist, specifically targets GluN1 and GluN2B subunits, also inhibits GIRK channels, and interacts with alpha1 adrenergic, serotonin, and sigma receptors.. |
| PC-61710 |
Irampanel hydrochloride
|
Irampanel (BIIR 561) is a combined antagonist of AMPA receptors (AMPAR) and voltage-dependent sodium channels. |
| PC-61515 |
Traxoprodil mesylate
|
A potent, selective N-methyl-D-aspartate (NMDA) antagonist with selectivity for the NR2B subunit. |
