| Cat. No. |
Product Name |
Information |
| PC-61716 |
DNQX disodium
AMPAR antagonist
|
DNQX disodium is the water soluble disodium salt of DNQX, which is a potent AMPA/kainate receptor antagonist with IC50 of 0.5/2.0 uM, respectively. |
| PC-61715 |
DNQX
AMPAR antagonist
|
DNQX (FG9041) is a potent AMPA/kainate receptor antagonist with IC50 of 0.5/2.0 uM, respectively. |
| PC-61714 |
Dasolampanel
AMPAR antagonist
|
Dasolampanel (NGX426) is an orally bioavailable, competitive antagonist of the AMPA-kainate receptors for the treatment of chronic pain conditions including neuropathic pain and migraine.. |
| PC-61713 |
Tezampanel
GluR5 antagonist
|
Tezampanel (LY 293558, NGX 424) is a competitive antagonist of the AMPA and kainate receptors with selectivity for the GluR5 subtype of the kainate receptor. |
| PC-61712 |
Selurampanel
AMPAR antagonist
|
Selurampanel (BGG 492) is a selective, orally active and competitive AMPA receptor (AMPAR) antagonist with IC50 of 0.19 uM. |
| PC-61711 |
Zonampanel
AMPAR antagonist
|
Zonampanel (YM 872) is a selective, potent and highly water-soluble, competitive AMPA receptor (AMPAR) antagonist with Ki of 96 nM. |
| PC-61709 |
Irampanel
AMPAR antagonist
|
Irampanel (BIIR 561) is a combined antagonist of AMPA receptors (AMPAR) and voltage-dependent sodium channels. |
| PC-61708 |
Kaitocephalin
iGluR antagonist
|
Kaitocephalin (PF 1191) is a non-selective ionotropic glutamate receptor (iGluR) antagonist, the first discovered natural toxin with protective properties against excitotoxic-death of cultured neurons induced by NMDA or AMPA/kainate receptors. |
| PC-61707 |
Becampanel
AMPAR antagonist
|
Becampanel (AMP 397) potent, competitive antagonist of the AMPA receptor (AMPAR) with IC50 of 11 nM. |
| PC-61706 |
Cyclothiazide
AMPAR PAM
|
Cyclothiazide (Doburil) is a positive allosteric modulator of the AMPA and kainate receptors that potentiates AMPA-mediated glutamate currents. |
| PC-61705 |
PF-04701475
AMPAR PAM
|
PF-04701475 is a potent positive allosteric modulator of AMPA receptor with EC50 of 123 nM, a prototype used to explore AMPAR-mediated pharmacology in vivo. |
| PC-61704 |
CX614
AMPAR PAM
|
CX614 is a positive allosteric modulator of AMPA receptors, shows neuroprotective effects for treatment of Parkinson's disease and Alzheimer's disease. |
