| Cat. No. |
Product Name |
Information |
| PC-61710 |
Irampanel hydrochloride
|
Irampanel (BIIR 561) is a combined antagonist of AMPA receptors (AMPAR) and voltage-dependent sodium channels. |
| PC-61709 |
Irampanel
|
Irampanel (BIIR 561) is a combined antagonist of AMPA receptors (AMPAR) and voltage-dependent sodium channels. |
| PC-61708 |
Kaitocephalin
|
Kaitocephalin (PF 1191) is a non-selective ionotropic glutamate receptor (iGluR) antagonist, the first discovered natural toxin with protective properties against excitotoxic-death of cultured neurons induced by NMDA or AMPA/kainate receptors. |
| PC-61707 |
Becampanel
|
Becampanel (AMP 397) potent, competitive antagonist of the AMPA receptor (AMPAR) with IC50 of 11 nM. |
| PC-61706 |
Cyclothiazide
|
Cyclothiazide (Doburil) is a positive allosteric modulator of the AMPA and kainate receptors that potentiates AMPA-mediated glutamate currents. |
| PC-61705 |
PF-04701475
|
PF-04701475 is a nove positive allosteric modulator of AMPA receptor, a prototype used to explore AMPAR-mediated pharmacology in vivo.. |
| PC-61704 |
CX-614
|
CX-614 is a positive allosteric modulator of AMPA receptors, shows neuroprotective effects for treatment of Parkinson's disease and Alzheimer's disease. |
| PC-61703 |
S-18986
|
S-18986 is an orally bioavailable and BBB penetrant positive allosteric modulator of AMPA receptors. |
| PC-61515 |
Traxoprodil mesylate
|
A potent, selective N-methyl-D-aspartate (NMDA) antagonist with selectivity for the NR2B subunit. |
| PC-61514 |
Traxoprodil
|
A potent, selective N-methyl-D-aspartate (NMDA) antagonist with selectivity for the NR2B subunit. |
| PC-61239 |
(S) 93-31
|
A pH-dependent, GluN2B-selective inhibitor of NMDA receptor with IC50 of 0.19 uM at pH6.9, 10-fold selecivity over brain tissue pH 7.6 (IC50=1.8 uM). |
| PC-60783 |
AICP
|
A potent, selective GluN2C-selective NMDA receptor glycine site superagonist with EC50 of 1.7 nM at GluN1/2C. |
