| Cat. No. |
Product Name |
Information |
| PC-61239 |
(S)93-31
GluN2B antagonist
|
(S)93-31 is a pH-dependent, GluN2B-selective inhibitor of NMDA receptor with IC50 of 0.19 uM at pH6.9, 10-fold selecivity over brain tissue pH 7.6 (IC50=1.8 uM). |
| PC-60899 |
LY3130481
AMPAR antagonist
|
LY3130481 (CERC611) is a potent, selective, noncompetitive TARP γ8-associated AMPA receptors with IC50 of 65.3 nM (GluA1/TARP γ-8), with no activity for γ-2 (cerebellum) or other TARP members. |
| PC-60783 |
AICP
GluN2C agonist
|
AICP is a potent, selective GluN2C-selective NMDA receptor glycine site superagonist with EC50 of 1.7 nM at GluN1/2C. |
| PC-60772 |
UBP 296
|
UBP 296 (UBP296, UBP-296) is a potent, and selective GluR5-subunit containing kainate receptor antagonist with Kd of 1.09 uM. |
| PC-60771 |
UBP 302
iGluR antagonist
|
UBP 302 (UBP-302) is a potent, and selective GluR5-subunit containing kainate receptor antagonist with Kd of 402 nM. |
| PC-45528 |
SYM2206
AMPAR antagonist
|
SYM2206 is an allosteric, non-competitive antagonist of the AMPA receptor with IC50 of 2.8 uM. |
| PC-45064 |
Rapastinel
NMDAR agonist
|
Rapastinel (GLYX-13, Thr-Pro-Pro-Thr-NH2) is a tetrapeptide (TPPT-amide) that acts as a NMDA receptor glycine site partial agonist. |
| PC-45533 |
CIQ
NMDAR potentiator
|
CIQ is a subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors. |
| PC-42745 |
LY450108
AMPAR PAM
|
LY450108 is a potent, selective, and centrally active positive allosteric modulator of AMPAR-mediated neurotransmission, which increase ion channel flux in the presence of agonist by suppressing desensitization and/or deactivation of the receptors. |
| PC-42744 |
LY451395
AMPAR PAM
|
Mibampator (LY451395) is a potent, selective, and centrally active positive allosteric modulator of AMPAR-mediated neurotransmission, which increase ion channel flux in the presence of agonist by suppressing desensitization and/or deactivation of the receptors. |
| PC-42691 |
Rislenemdaz
GluN2B antagonist
|
Rislenemdaz (MK-0657, CERC-301) is a potent, orally bioavailable brain‐penetrant, NR2B-selective NMDA receptor (GluN2B) antagonist with Ki and IC 50 of 8.1 nM and 3.6 nM respectively, with no off-target activity. |
| PC-45532 |
L-701324
NMDAR antagonist
|
L-701324 (L-701,324) is a potent, orally active antagonist at the glycine modulatory site on NMDA receptor with IC50 of 2 nM. |
