| Cat. No. |
Product Name |
Information |
| PC-43076 |
Naspm trihydrochloride
AMPAR antagonist
|
Naspm is a selective antagonist of Ca2+-permeable AMPA receptors, blocks GluR2-lacking AMPARs, suppresses current responses induced by kainate in type II neurons with IC50 of 0.33 uM. |
| PC-43075 |
Naspm
AMPAR antagonist
|
Naspm is a selective antagonist of Ca2+-permeable AMPA receptors, blocks GluR2-lacking AMPARs, suppresses current responses induced by kainate in type II neurons with IC50 of 0.33 uM. |
| PC-43074 |
CX546
AMPAR PAM
|
CX546 is an AMPA receptor potentiator and GluR activator, binds specifically to the agonist bound non-desensitized receptor. |
| PC-43072 |
CFM-2
AMPAR antagonist
|
CFM-2 is a selective, non-competitive AMPA receptor antagonist. |
| PC-43066 |
(S)-Willardiine
AMPAR agonist
|
(S)-Willardiine is a potent agonist of AMPA/kainate receptors with EC50 of 44.8 uM. |
| PC-42958 |
PEAQX tetrasodium hydrate
NR2A-NMDA receptor antagonist
|
PEAQX (NVP-AAM077) is a potent, selective, NR2A-preferring NMDA receptor antagonist with IC50 of 270 nM (NR1A/2A), >100-fold selectivity over NR1A/2B receptor (IC50=29,600 nM). |
| PC-42957 |
PEAQX
NR2A-NMDA receptor antagonist
|
PEAQX (NVP-AAM077) is a potent, selective, NR2A-preferring NMDA receptor antagonist with IC50 of 270 nM (NR1A/2A), >100-fold selectivity over NR1A/2B receptor (IC50=29,600 nM). |
| PC-63023 |
LY 392098
AMPAR PAM
|
LY 392098 is a selective, potent and centrally active positive allosteric modulator of AMPAR. |
| PC-62087 |
HBT1
AMPAR PAM
|
HBT1 is a novel potent AMPA receptor potentiator with lower agonistic effect compared with LY451395 and OXP1. |
| PC-61911 |
Rislenemdaz mesylate
GluN2B antagonist
|
Rislenemdaz mesylate (MK 0657, CERC 301) is a potent, orally bioavailable, brain‐penetrant, NR2B-selective NMDA receptor (GluN2B) antagonist with Ki and IC 50 of 8.1 nM and 3.6 nM respectively, with no off-target activity. |
| PC-61909 |
Rislenemdaz hydrochloride
GluN2B antagonist
|
Rislenemdaz (MK 0657, CERC 301) is a potent, orally bioavailable, brain‐penetrant, NR2B-selective NMDA receptor (GluN2B) antagonist with Ki and IC 50 of 8.1 nM and 3.6 nM respectively, with no off-target activity. |
| PC-61864 |
PF-04958242
AMPAR PAM
|
PF-04958242 (Pesampator) is a novel potent, selctive, and orally-active AMPA receptor (AMPAR) positive allosteric modulator (PAM) with Ki of 170 nM, EC50 of 370 nM. |
