| Cat. No. |
Product Name |
Information |
| PC-61726 |
Tulrampator
AMPAR PAM
|
Tulrampator (S 47445, CX 1632) is a potent, selective, positive allosteric modulator of AMPA receptor (AMPAR) with EC50 of 2.5-5.4 uM for different AMPA receptors subtypes (GluA1/2/4 flip and flop variants). |
| PC-61725 |
GYKI 52466 dihydrochloride
AMPAR antagonist
|
GYKI 52466 is a selective, non-competitive, orally active AMPA receptor (AMPAR) antagonist with IC50 of 10-20 uM against AMPA-induced responses. |
| PC-61724 |
LY-404187
AMPAR PAM
|
LY-404187 is a potent, selective, positive allosteric modulator of AMPA receptor (AMPAR) with EC50 of 1.3 uM. |
| PC-61722 |
LY-503430
AMPAR agonist
|
LY-503430 is a novel AMPA receptor (AMPAR) potentiator that selectively enhances glutamate-induced calcium influx into HEK293 cells transfected with human GLUA1, GLUA2, GLUA3, or GLUA4 AMPA receptors with EC50 of 0.1-4 uM. |
| PC-61721 |
IDRA-21
AMPAR PAM
|
IDRA-21 is a positive allosteric modulator of the AMPA receptor (AMPAR). |
| PC-61719 |
NBQX
AMPAR antagonist
|
NBQX is a potent, selective and competitive AMPA receptor (AMPAR) antagonist with IC50 of 0.15 uM. |
| PC-61717 |
CNQX
AMPAR antagonist
|
CNQX (FG 9065) is a potent AMPA/kainate receptor antagonist with IC50 of 0.3/1.5 uM, respectively. |
| PC-61715 |
DNQX
AMPAR antagonist
|
DNQX (FG9041) is a potent AMPA/kainate receptor antagonist with IC50 of 0.5/2.0 uM, respectively. |
| PC-61714 |
Dasolampanel
AMPAR antagonist
|
Dasolampanel (NGX426) is an orally bioavailable, competitive antagonist of the AMPA-kainate receptors for the treatment of chronic pain conditions including neuropathic pain and migraine.. |
| PC-61713 |
Tezampanel
GluR5 antagonist
|
Tezampanel (LY 293558, NGX 424) is a competitive antagonist of the AMPA and kainate receptors with selectivity for the GluR5 subtype of the kainate receptor. |
| PC-61712 |
Selurampanel
AMPAR antagonist
|
Selurampanel (BGG 492) is a selective, orally active and competitive AMPA receptor (AMPAR) antagonist with IC50 of 0.19 uM. |
| PC-61711 |
Zonampanel
AMPAR antagonist
|
Zonampanel (YM 872) is a selective, potent and highly water-soluble, competitive AMPA receptor (AMPAR) antagonist with Ki of 96 nM. |
