| Cat. No. |
Product Name |
Information |
| PC-45528 |
SYM2206
AMPAR antagonist
|
SYM2206 is an allosteric, non-competitive antagonist of the AMPA receptor with IC50 of 2.8 uM. |
| PC-45064 |
Rapastinel
NMDAR agonist
|
Rapastinel (GLYX-13, Thr-Pro-Pro-Thr-NH2) is a tetrapeptide (TPPT-amide) that acts as a NMDA receptor glycine site partial agonist. |
| PC-45533 |
CIQ
NMDAR potentiator
|
CIQ is a subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors. |
| PC-42745 |
LY450108
AMPAR PAM
|
LY450108 is a potent, selective, and centrally active positive allosteric modulator of AMPAR-mediated neurotransmission, which increase ion channel flux in the presence of agonist by suppressing desensitization and/or deactivation of the receptors. |
| PC-42744 |
LY451395
AMPAR PAM
|
Mibampator (LY451395) is a potent, selective, and centrally active positive allosteric modulator of AMPAR-mediated neurotransmission, which increase ion channel flux in the presence of agonist by suppressing desensitization and/or deactivation of the receptors. |
| PC-42691 |
Rislenemdaz
GluN2B antagonist
|
Rislenemdaz (MK-0657, CERC-301) is a potent, orally bioavailable brain‐penetrant, NR2B-selective NMDA receptor (GluN2B) antagonist with Ki and IC 50 of 8.1 nM and 3.6 nM respectively, with no off-target activity. |
| PC-45532 |
L-701324
NMDAR antagonist
|
L-701324 (L-701,324) is a potent, orally active antagonist at the glycine modulatory site on NMDA receptor with IC50 of 2 nM. |
| PC-42742 |
Aniracetam
AMPAR PAM
|
Aniracetam (Ro 13-5057) is a positive allosteric modulator of AMPAR, potentiates the iQA responses induced in Xenopus oocytes by rat brain mRNA in a reversible manner. |
| PC-42743 |
Ampalex
AMPAR PAM
|
Ampalex (CX516) is a positive allosteric modulator of AMPA, increases fast, excitatory (glutamatergic) synaptic responses in hippocampal slices by about 50% with an EC50 of 170 uM. |
| PC-42746 |
Farampator
AMPAR PAM
|
Farampator (CX-691, Org24448) is a positive allosteric modulator of AMPAR as ampakine agent. |
| PC-22610 |
NS3763
GLUK5 antagonist
|
NS3763 is a noncompetitive antagonist of GLUK5 receptor, inhibits domoate-induced increase in intracellular calcium mediated through the GLU(K5) of kainate receptors with IC50 of 1.6 uM, with no effect on GLU(K6) subtype. |
| PC-22609 |
3-Hydroxykynurenine
iGluR modulator
|
3-Hydroxykynurenine (3-HK) is a metabolite produced through host tryptophan metabolism, restricts bacterial expansion in macrophages via a systemic mechanism, modulates the activity of iGluR receptors of the AMPAR and KAR subclasses. |
