| Cat. No. |
Product Name |
Information |
| PC-43279 |
Eliprodil
GluN2B antagonist
|
Eliprodil (SL-820715) is a non-competitive NR2B-NMDA receptor (GluN2B) antagonist with IC50 of 1 uM, less potent for NR2A- and NR2C-containing receptors (IC50>100 uM). |
| PC-63207 |
NAB-14
GluN2C/2D modulator
|
NAB-14 is a potent, selective negative allosteric modulator of GluN2C/2D-containing NMDA receptors with IC50 of 580 nM, >800-fold selective over GluN2A/GluN2 receptors. |
| PC-43078 |
PEPA
AMPAR PAM
|
PEPA is an allosteric potentiator of AMPA receptors, potentiates glutamate responses by 50-fold in oocytes expressing GluRCflop (EC50=50 uM). |
| PC-43077 |
CMPDA
GluR2 PAM
|
CMPDA is a potent positive allosteric modulator of GluR2 receptors with EC50 of 45.4 and 63.4 nM at GluR2i and GluR2o respectively, in a calcium influx screening assays. |
| PC-43076 |
Naspm trihydrochloride
AMPAR antagonist
|
Naspm is a selective antagonist of Ca2+-permeable AMPA receptors, blocks GluR2-lacking AMPARs, suppresses current responses induced by kainate in type II neurons with IC50 of 0.33 uM. |
| PC-43075 |
Naspm
AMPAR antagonist
|
Naspm is a selective antagonist of Ca2+-permeable AMPA receptors, blocks GluR2-lacking AMPARs, suppresses current responses induced by kainate in type II neurons with IC50 of 0.33 uM. |
| PC-43074 |
CX546
AMPAR PAM
|
CX546 is an AMPA receptor potentiator and GluR activator, binds specifically to the agonist bound non-desensitized receptor. |
| PC-43072 |
CFM-2
AMPAR antagonist
|
CFM-2 is a selective, non-competitive AMPA receptor antagonist. |
| PC-43066 |
(S)-Willardiine
AMPAR agonist
|
(S)-Willardiine is a potent agonist of AMPA/kainate receptors with EC50 of 44.8 uM. |
| PC-42958 |
PEAQX tetrasodium hydrate
NR2A-NMDA receptor antagonist
|
PEAQX (NVP-AAM077) is a potent, selective, NR2A-preferring NMDA receptor antagonist with IC50 of 270 nM (NR1A/2A), >100-fold selectivity over NR1A/2B receptor (IC50=29,600 nM). |
| PC-42957 |
PEAQX
NR2A-NMDA receptor antagonist
|
PEAQX (NVP-AAM077) is a potent, selective, NR2A-preferring NMDA receptor antagonist with IC50 of 270 nM (NR1A/2A), >100-fold selectivity over NR1A/2B receptor (IC50=29,600 nM). |
| PC-63023 |
LY 392098
AMPAR PAM
|
LY 392098 is a selective, potent and centrally active positive allosteric modulator of AMPAR. |
