| Cat. No. |
Product Name |
Information |
| PC-49461 |
C101248
THIK-1 inhibitor
|
C101248 is the first selective small-molecule inhibitor of tandem pore domain halothane-inhibited K+ channel 1 (THIK-1) with IC50 of 50 nM for both mouse and human THIK-1. |
| PC-47105 |
TTQC-1
BKCa activator
|
TTQC-1 is a potent activator of the large-conductance Ca2+-activated K+ channel (BKCa channel), directly and reversibly activates the macroscopic current of BKCa channels expressed in Xenopus oocytes from both sides of the cellular membrane, increases the maximum conductance and shifted the half activation voltage to the left with EC50 of 2.8 uM. |
| PC-47099 |
SKA-31
KCa2/KCa3.1 activator
|
SKA-31 is a small molecule activator of KCa2 and KCa3.1 potassium channels with EC50 values of 260, 2900, 2900 nM for KCa3.1, KCa2.1 and KCa2.2 respectively. |
| PC-38848 |
KV10.1 inhibitor compound 1
Kv10.1 inhibitor
|
KV10.1 inhibitor compound 1 is a selective inhibitor of the voltage-gated potassium channel KV10.1 with IC50 of 740 nM. |
| PC-38847 |
ZVS-08
Kv10.1 inhibitor
|
ZVS-08 is a selective inhibitor of the voltage-gated potassium channel KV10.1 with IC50 of 3.7 uM. |
| PC-38639 |
3hi2one-G4
GIRK4 activator
|
3hi2one-G4 is a highly selective small molecule activator targeting GIRK4 homomeric channels, does not activate GIRK2, GIRK1/2 or GIRK1/4 channels. |
| PC-38493 |
RY785
Kv2 channel inhibitor
|
RY785 (RY-785) is a potent, selective voltage-gated potassium (Kv2) channels inhibitor with IC50 of 50 nM for Kv2.1 channel, possesses good selectivity over Kv1.2 (IC50>10 uM). |
| PC-38451 |
BMS-191011
KCa1.1/BK opener
|
BMS-191011 (BMS-A) is a small molecule activator of large-conductance calcium-activated potassium (KCa1.1/BK) channels, increases current to 126% over control at 1 uM. |
| PC-73403 |
Bafrekalant
Potassium channel blocker
|
Bafrekalant is a small molecule potassium channel blocker with the potential for the research of breathing disorders. |
| PC-73253 |
Lu AA41178
Kv7 channels opener
|
Lu AA41178 is a potent, pan-selective Kv7.2-7.5 opener with EC50 of 1.5, 0.6 20.5, and 37.0 uM for Kv7.2, Kv7.2/7.3, Kv7.4 and Kv7.5, respectively. |
| PC-73241 |
KNa1.1 inhibitor 31
KNa1.1 (Slack) inhibitor
|
KNa1.1 inhibitor 31 is a potent, selective, orally available inhibitor of sodium-activated potassium channel KNa1.1 (Slack, Slo2.2) with IC50 of 40 nM (hKNa1.1 WT). |
| PC-73240 |
VU0606170
KNa1.1 inhibitor
|
VU 0606170 is a selective sodium-activated potassium channel KNa1.1 (Slack, Slo2.2) inhibitor with EC50 of 1.84 and 1.16 uM for WT Slack and A934T Slack, repectively. |
