| Cat. No. |
Product Name |
Information |
| PC-62767 |
BMS-919373
Kv1.5 inhibitor
|
BMS-919373 is a potent I(Kur)/Kv1.5 channel blocker with IC50 of 50 nM, with selectivity versus hERG, Na, Ca channels and reduced the level of brain penetration. |
| PC-62646 |
PAPTP
Kv1.3 inhibitor
|
PAPTP is a PAP-1 derivative, potent, specific Kv1.3 channel inhibitor with IC50 of 31 nM in Jurkat T lymphocytes by patch-clamp, reduces cell viability and efficiently kills B16F10 cancer cells at 1 uM. |
| PC-62645 |
PCARBTP
Kv1.3 inhibitor
|
PCARBTP is a derivative, potent, specific Kv1.3 channel inhibitor, reduces cell viability and efficiently kills B16F10 cancer cells at 1 uM. |
| PC-62358 |
ML133
Kir2.1 inhibitor
|
ML133 (CID781301) is a potent, selective K(ir)2.1 potassium channel with IC50 of 1.8 uM at pH 7.4 and 290 nM at pH 8.5, respectively. |
| PC-62357 |
ML133 hydrochloride
Kir2.1 inhibitor
|
ML133 (CID781301) is a potent, selective K(ir)2.1 potassium channel with IC50 of 1.8 uM at pH 7.4 and 290 nM at pH 8.5, respectively. |
| PC-62203 |
Psora-4
Kv1.3 inhibitor
|
Psora-4 is a potent and selective Kv1.3 potassium channel blocker with EC50 of 3 nM. |
| PC-62092 |
GI-530159
TERK opener
|
GI-530159 (ICA-069771) is a novel potent, selective, mechano-sensitive K2P channel (TERK) opener with EC50 of 1 uM for TERK1. |
| PC-62064 |
VU 0240551
KCC2 inhibitor
|
VU 0240551 is a potent, selecticve inhibitor of the neuronal K-Cl cotransporter KCC2 with IC50 of 568 nM in K+ uptake assay in KCC2-overexpressing cells. |
| PC-61462 |
NS-5806
Kv4.3 activator
|
NS-5806 (NS5806) is a potent Kv4.3 channel activator that mediates the transient outward K+ current (Ito). |
| PC-70331 |
ML297
GIRK1/2 activator
|
ML297 (VU 0456810) is a potent, selective, CNS-penetrant small molecule agonist of GIRK1/2 channel with EC50 of 160 nM. |
| PC-70312 |
RU-TRAAK-2
|
RU-TRAAK-2 is a completely reversible TRAAK inhibitor, shows no activity for non-K2P channels (Kv1.2, Slo1 and GIRK2). |
| PC-70311 |
RU-TRAAK-1
|
RU-TRAAK-1 is a poorly reversible TRAAK inhibitor, shows no activity for non-K2P channels (Kv1.2, Slo1 and GIRK2). |
