| Cat. No. |
Product Name |
Information |
| PC-60229 |
NS15370
Kv.7 activator
|
NS15370 is a highly potent positive modulator of Kv7 channels with EC50 of 100 nM (Kv7.2-Kv7.5). |
| PC-60228 |
ML213
Kv7.2/Kv7.4 activator
|
ML213 is a potent, selective KCNQ2 (Kv7.2) and KCNQ4 (Kv7.4) activator with EC50 of 230 and 510 nM, respectively. |
| PC-60191 |
ML67-33
K2P channel activator
|
ML67-33 is a low micromolar (EC50=9.7 uM, K2P2.1), selective activator of temperature- and mechano-sensitive K2P potassium channels. |
| PC-42123 |
Nigericin sodium
Potassium ionophore, NLRP3 agonist
|
Nigericin sodium (NSC 292567) is an ionophore antibiotic derived from S. hygroscopicus that acts as a potassium ionophore promoting K+/H+ exchange across mitochondrial membranes. |
| PC-46826 |
Mitiglinide calcium hydrate
KATP channel inhibitor
|
Mitiglinide calcium hydrate is an insulin secretion stimulator by closing the ATP-sensitive potassium KATP channels in pancreatic β cells, has potent hypoglycemic effects. |
| PC-45221 |
Mitiglinide calcium
KATP channel inhibitor
|
Mitiglinide calcium is an insulin secretion stimulator by closing the ATP-sensitive potassium KATP channels in pancreatic β cells, has potent hypoglycemic effects. |
| PC-45091 |
NS-1643
hERG activator
|
A small molecule activator of hERG channels that enhances the magnitude of wild-type hERG current in a concentration- and voltage-dependent manner with EC50 of 10.4 uM at -10 mV. |
| PC-45127 |
Flupirtine
Kv7 activator
|
A selective neuronal potassium channel (KCNQ/KV7 channel) activator that also has indirect NMDA receptor antagonist and GABAA receptor modulatory properties. |
| PC-45126 |
Flupirtine maleate
Kv7 activator
|
Flupirtine maleate (D-9998) is a selective neuronal potassium channel (KCNQ/KV7 channel) activator that also has indirect NMDA receptor antagonist and GABAA receptor modulatory properties. |
| PC-42069 |
PAP-1
Kv1.3 inhibitor
|
PAP-1 is a potent, selective small molecule lymphocyte K+ channel Kv1.3 blocker with EC50 of 2 nM. |
| PC-45844 |
Senicapoc
KCa3.1 inhibitor
|
Senicapoc (ICA-17043) is a potent, selective Gardos channel (KCa3.1) blocker that blocks Ca(2+)-induced rubidium flux from human RBCs (IC50=11 nM) and inhibits RBC dehydration (IC50=10-50 nM). |
| PC-42381 |
GAL-021
BKCa inhibitor
|
GAL-021 is a respiratory stimulant that acts as a potent calcium-activated potassium (BKCa, KCa1.1) channel blocker blocker. |
