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Cat. No. Product Name Information
PC-42123

Nigericin sodium

Potassium ionophore, NLRP3 agonist

Nigericin sodium (NSC 292567) is an ionophore antibiotic derived from S. hygroscopicus that acts as a potassium ionophore promoting K+/H+ exchange across mitochondrial membranes.
PC-46826

Mitiglinide calcium hydrate

KATP channel inhibitor

Mitiglinide calcium hydrate is an insulin secretion stimulator by closing the ATP-sensitive potassium KATP channels in pancreatic β cells, has potent hypoglycemic effects.
PC-45221

Mitiglinide calcium

KATP channel inhibitor

Mitiglinide calcium is an insulin secretion stimulator by closing the ATP-sensitive potassium KATP channels in pancreatic β cells, has potent hypoglycemic effects.
PC-45091

NS-1643

hERG activator

A small molecule activator of hERG channels that enhances the magnitude of wild-type hERG current in a concentration- and voltage-dependent manner with EC50 of 10.4 uM at -10 mV.
PC-45127

Flupirtine

Kv7 activator

A selective neuronal potassium channel (KCNQ/KV7 channel) activator that also has indirect NMDA receptor antagonist and GABAA receptor modulatory properties.
PC-45126

Flupirtine maleate

Kv7 activator

Flupirtine maleate (D-9998) is a selective neuronal potassium channel (KCNQ/KV7 channel) activator that also has indirect NMDA receptor antagonist and GABAA receptor modulatory properties.
PC-42069

PAP-1

Kv1.3 inhibitor

PAP-1 is a potent, selective small molecule lymphocyte K+ channel Kv1.3 blocker with EC50 of 2 nM.
PC-45844

Senicapoc

KCa3.1 inhibitor

Senicapoc (ICA-17043) is a potent, selective Gardos channel (KCa3.1) blocker that blocks Ca(2+)-induced rubidium flux from human RBCs (IC50=11 nM) and inhibits RBC dehydration (IC50=10-50 nM).
PC-42381

GAL-021

BKCa inhibitor

GAL-021 is a respiratory stimulant that acts as a potent calcium-activated potassium (BKCa, KCa1.1) channel blocker blocker.
PC-46030

Dronedarone

Potassium channel inhibitor

Dronedarone (SR33589) is a multichannel blocker agent that has antiarrhythmic activity, reduces the late sustained K(+) current, I(K) (or Isus) with EC50 of 0.85 uM in postmyocardial infarcted (PMI) rats.
PC-45962

Dronedarone hydrochloride

Dronedarone hydrochloride (SR33589) is a multichannel blocker agent that has antiarrhythmic activity, reduces the late sustained K(+) current, I(K) (or Isus) with EC50 of 0.85 uM in postmyocardial infarcted (PMI) rats.
PC-45472

Azimilide dihydrochloride

hERG inhibitor

Azimilide dihydrochloride is a class ΙΙΙ antiarrhythmic agent that blocks hERG channel; blocks HERG channel at 0.1 and 1 Hz with IC50s of 1.4 uM and 5.2 uM respectively.

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