| Cat. No. |
Product Name |
Information |
| PC-60837 |
BeKm-1
hERG inhibitor
|
BeKm-1 is a potent, selective peptide inhibitor of hERG channel with IC50 of 3.3 nM for hERG1 channels. |
| PC-60836 |
AZSMO-23
hERG activator
|
AZSMO-23 (AZSMO 23, AZSMO23) is a potent hERG potassium channel (Kv11.1) activator that activates WT hERG pre-pulse and tail current with EC50 of 28.6 and 11.2 μM respectively. |
| PC-60835 |
ML-T531
hERG activator
|
ML-T531 (CFK332-B) is a potent, selective hERG potassium channel (Kv11.1) activator with EC50 of 3.13 uM. |
| PC-60834 |
PD-307243
hERG activator
|
A potent hERG channel activator that concentration-dependently increases the hERG current (2.1 and 3.4-fold at 3 and 10 uM, respectively) and markedly slows hERG channel deactivation and inactivation. |
| PC-60833 |
NS3623
hERG activator
|
NS3623 is a novel human RBC Cl-conductance blocker (IC50=210 nM) and HERG channel activitor (EC50=79.4 uM, HERG1 channel activation). |
| PC-60832 |
ICA-105574
hERG activator
|
ICA-105574 is a potent and efficacious hERG channel activator steeply potentiates current amplitudes more than 10-fold with EC50 of 0.5 uM. |
| PC-60831 |
ITP-2
hERG activator
|
ITP-2 is a novel small molecule activator of Kv11.1 (hERG) channel (216% over control at 3 uM for hERG1a activation). |
| PC-60824 |
ICA-27243
Kv7.2/Kv7.3 activator
|
ICA-27243 (ICA-207243) is a potent, selective KCNQ2/Q3 (Kv7.2/Kv7.3) potassium channel opener/activator with EC50 of 0.38 uM. |
| PC-60823 |
ICA-069673
Kv7.2/Kv7.3 activator
|
ICA-069673 (ICA069673) is a novel potent, selective and orally active KCNQ2/Q3 (Kv7.2/Kv7.3) potassium channel opener/activator with EC50 of 0.69 uM, 20-fold selectivity over KCNQ3/Q5. |
| PC-60806 |
RY796
Kv2 channel inhibitor
|
RY796 is a potent, selective Kv2 channel inhibitor that potently inhibits Kv2.1 and Kv2.2 with IC50 of 0.14 and 0.09 uM, respectively. |
| PC-60805 |
RY796 racemate
Kv2 inhibitor
|
RY796 racemate is the racemate form of RY796, a potent, selective Kv2 channel inhibitor that potently inhibits Kv2.1 and Kv2.2. |
| PC-60782 |
NS13001
KCa2.2/KCa2.3 inhibitor
|
NS13001 is a potent, selective, allosteric and orally acitve positive modulator of small-conductance calcium-activated K+ channel KCa2.2 and KCa2.3 with EC50 of 1.6 and 0.14 uM, respectively. |
