| Cat. No. |
Product Name |
Information |
| PC-47099 |
SKA-31
KCa2/KCa3.1 activator
|
SKA-31 is a small molecule activator of KCa2 and KCa3.1 potassium channels with EC50 values of 260, 2900, 2900 nM for KCa3.1, KCa2.1 and KCa2.2 respectively. |
| PC-38848 |
KV10.1 inhibitor compound 1
Kv10.1 inhibitor
|
KV10.1 inhibitor compound 1 is a selective inhibitor of the voltage-gated potassium channel KV10.1 with IC50 of 740 nM. |
| PC-38847 |
ZVS-08
Kv10.1 inhibitor
|
ZVS-08 is a selective inhibitor of the voltage-gated potassium channel KV10.1 with IC50 of 3.7 uM. |
| PC-38639 |
3hi2one-G4
GIRK4 activator
|
3hi2one-G4 is a highly selective small molecule activator targeting GIRK4 homomeric channels, does not activate GIRK2, GIRK1/2 or GIRK1/4 channels. |
| PC-38493 |
RY785
Kv2 channel inhibitor
|
RY785 (RY-785) is a potent, selective voltage-gated potassium (Kv2) channels inhibitor with IC50 of 50 nM for Kv2.1 channel, possesses good selectivity over Kv1.2 (IC50>10 uM). |
| PC-38451 |
BMS-191011
KCa1.1/BK opener
|
BMS-191011 (BMS-A) is a small molecule activator of large-conductance calcium-activated potassium (KCa1.1/BK) channels, increases current to 126% over control at 1 uM. |
| PC-73403 |
Bafrekalant
Potassium channel blocker
|
Bafrekalant is a small molecule potassium channel blocker with the potential for the research of breathing disorders. |
| PC-73253 |
Lu AA41178
Kv7 channels opener
|
Lu AA41178 is a potent, pan-selective Kv7.2-7.5 opener with EC50 of 1.5, 0.6 20.5, and 37.0 uM for Kv7.2, Kv7.2/7.3, Kv7.4 and Kv7.5, respectively. |
| PC-73241 |
KNa1.1 inhibitor 31
KNa1.1 (Slack) inhibitor
|
KNa1.1 inhibitor 31 is a potent, selective, orally available inhibitor of sodium-activated potassium channel KNa1.1 (Slack, Slo2.2) with IC50 of 40 nM (hKNa1.1 WT). |
| PC-73240 |
VU0606170
KNa1.1 inhibitor
|
VU 0606170 is a selective sodium-activated potassium channel KNa1.1 (Slack, Slo2.2) inhibitor with EC50 of 1.84 and 1.16 uM for WT Slack and A934T Slack, repectively. |
| PC-73230 |
Benzopyran-G1
Kir3.1 channel inhibitor
|
Benzopyran-G1 (Benzopyran G1, BP-G1) is a potent and selective small-molecule inhibitor targeting Kir3.1-containing channels, inhibits heteromeric Kir3.1/4 or Kir3.1/2 channels with IC50 of 10-30 nM. |
| PC-73222 |
NS8593 hydrochloride
SK channel inhibitor
|
NS8593 is a potent and selective small conductance Ca2+-activated K+ channels (SK channels) inhibitor, reversibly inhibits recombinant SK3-mediated currents with potencies around 100 nM. |
