| Cat. No. |
Product Name |
Information |
| PC-38451 |
BMS-191011
KCa1.1/BK opener
|
BMS-191011 (BMS-A) is a small molecule activator of large-conductance calcium-activated potassium (KCa1.1/BK) channels, increases current to 126% over control at 1 uM. |
| PC-73403 |
Bafrekalant
Potassium channel blocker
|
Bafrekalant is a small molecule potassium channel blocker with the potential for the research of breathing disorders. |
| PC-73253 |
Lu AA41178
Kv7 channels opener
|
Lu AA41178 is a potent, pan-selective Kv7.2-7.5 opener with EC50 of 1.5, 0.6 20.5, and 37.0 uM for Kv7.2, Kv7.2/7.3, Kv7.4 and Kv7.5, respectively. |
| PC-73241 |
KNa1.1 inhibitor 31
KNa1.1 (Slack) inhibitor
|
KNa1.1 inhibitor 31 is a potent, selective, orally available inhibitor of sodium-activated potassium channel KNa1.1 (Slack, Slo2.2) with IC50 of 40 nM (hKNa1.1 WT). |
| PC-73240 |
VU0606170
KNa1.1 inhibitor
|
VU 0606170 is a selective sodium-activated potassium channel KNa1.1 (Slack, Slo2.2) inhibitor with EC50 of 1.84 and 1.16 uM for WT Slack and A934T Slack, repectively. |
| PC-73230 |
Benzopyran-G1
Kir3.1 channel inhibitor
|
Benzopyran-G1 (Benzopyran G1, BP-G1) is a potent and selective small-molecule inhibitor targeting Kir3.1-containing channels, inhibits heteromeric Kir3.1/4 or Kir3.1/2 channels with IC50 of 10-30 nM. |
| PC-73222 |
NS8593 hydrochloride
SK channel inhibitor
|
NS8593 is a potent and selective small conductance Ca2+-activated K+ channels (SK channels) inhibitor, reversibly inhibits recombinant SK3-mediated currents with potencies around 100 nM. |
| PC-73206 |
NS 11021
BKCa (KCa1.1) activator
|
NS11021 is a potent and specific activator of large-conductance Ca2+-activated potassium channels (BKCa/KCa1.1). |
| PC-73196 |
XEN1101
Kv7.2/Kv7.3 opener
|
XEN1101 (Azetukalner) is a small molecule activator/opener of Kv7.2/Kv7.3 (KCNQ2/3) potassium channel with potential for relieving pain. |
| PC-73038 |
Kv2.1-syntaxin inhibitor 15
Kv2.1-syntaxin inhibitor
|
Kv2.1-syntaxin inhibitor 15 (Kv2.1-syntaxin-IN-15, Cpd5) is a small molecule Kv2.1-syntaxin-binding inhibitor (IC50=5.5 uM) with neuroprotective properties. |
| PC-72872 |
VU6036720
Kir4.1/Kir5.1 inhibitor
|
VU6036720 (VU 6036720) is the first potent, selective inhibitor of heteromeric Kir4.1/Kir5.1 (KCNJ10/KCNJ16) with IC50 of 0.24 uM. |
| PC-72820 |
VU0468554
GIRK inhibitor
|
VU0468554 (VU 0468554) is a potent, selective inhibitor of GIRK channel with IC50 of 0.85 and 2.6 uM for GIRK1/GIRK4 and GIRK1/GIRK2 in cellular assays. |
