| Cat. No. |
Product Name |
Information |
| PC-42069 |
PAP-1
Kv1.3 inhibitor
|
PAP-1 is a potent, selective small molecule lymphocyte K+ channel Kv1.3 blocker with EC50 of 2 nM. |
| PC-45844 |
Senicapoc
KCa3.1 inhibitor
|
Senicapoc (ICA-17043) is a potent, selective Gardos channel (KCa3.1) blocker that blocks Ca(2+)-induced rubidium flux from human RBCs (IC50=11 nM) and inhibits RBC dehydration (IC50=10-50 nM). |
| PC-42381 |
GAL-021
BKCa inhibitor
|
GAL-021 is a respiratory stimulant that acts as a potent calcium-activated potassium (BKCa, KCa1.1) channel blocker blocker. |
| PC-46030 |
Dronedarone
Potassium channel inhibitor, USP11 inhibitor
|
Dronedarone (SR33589) is a multichannel blocker agent that has antiarrhythmic activity, reduces the late sustained K(+) current, I(K) (or Isus) with EC50 of 0.85 uM in postmyocardial infarcted (PMI) rats. |
| PC-45962 |
Dronedarone hydrochloride
|
Dronedarone hydrochloride (SR33589) is a multichannel blocker agent that has antiarrhythmic activity, reduces the late sustained K(+) current, I(K) (or Isus) with EC50 of 0.85 uM in postmyocardial infarcted (PMI) rats. |
| PC-45472 |
Azimilide dihydrochloride
hERG inhibitor
|
Azimilide dihydrochloride is a class ΙΙΙ antiarrhythmic agent that blocks hERG channel; blocks HERG channel at 0.1 and 1 Hz with IC50s of 1.4 uM and 5.2 uM respectively. |
| PC-45471 |
Azimilide
hERG inhibitor
|
Azimilide (NE-10064) is a class ΙΙΙ antiarrhythmic agent that blocks hERG channel, blocks HERG channel at 0.1 and 1 Hz with IC50s of 1.4 uM and 5.2 uM respectively. |
| PC-47402 |
Quinidine
|
A class I antiarrhythmic agent (Ia) that works by blocking the fast inward sodium current (INa). |
| PC-27005 |
K2P16-i7-4
TALK-1 inhibitor
|
K2P16-i7-4 is a potent, selective, reversible inhibitor of two-pore domain K+ (K2P) channel TALK-1 with IC50 of 1.61 uM, enhances [Ca2+]ER storage in T-REx-TALK-1 cells. |
| PC-27004 |
K2P16-i7
TALK-1 inhibitor
|
K2P16-i7 (VU0544194) is a potent, selective, reversible inhibitor of two-pore domain K+ (K2P) channel TALK-1 with IC50 of 5.2 uM, promotes β-cell function. |
| PC-26897 |
Zinc13732787
KCNQ1/Kv7.1 inhibitor
|
Zinc13732787 is a selective inhibitor of KCNQ1/Kv7.1 potassium channel, without affecting KCNQ2/KCNQ3. |
| PC-26855 |
VU0521426
Kv3.1 channel inhibitor
|
VU0521426 (VU426) is a potent, selective Kv3.1 channel inhibitor with IC50 of 4.3 uM, suppresses Kv3.1 activity413through a state-dependent mechanism consistent with stabilization of non-conducting channel states. |
