| Cat. No. |
Product Name |
Information |
| PC-60574 |
VU714 oxalate
Kir7.1 inhibitor
|
VU714 oxalate is a potent inwardly rectifying K+ channel Kir7.1 inhibitor with IC50 of 5.6 uM in T1+ flux assays. |
| PC-60573 |
VU714
Kir7.1 inhibitor
|
VU714 is a potent inwardly rectifying K+ channel Kir7.1 inhibitor with IC50 of 5.6 uM in T1+ flux assays. |
| PC-60572 |
MRT2000769
Kir7.1 inhibitor
|
MRT2000769 is a potent Kir7.1 inhibitor with IC50 of 2.0 uM, induces long-lasting uterine contractility similar to those observed with VU590. |
| PC-60571 |
VU591
ROMK inhibitor
|
VU591 is a potent, selective renal outer medullary potassium channel (ROMK, Kir1.1) inhibitor with IC50 of 0.24 uM in T1+ flux assays. |
| PC-60570 |
VU590 dihydrochloride
ROMK inhibitor
|
VU590 is the first small-molecule inhibitor of renal outer medullary potassium channel (ROMK, Kir1.1) and Kir7.1 with IC50 of 294 nM for ROMK. |
| PC-60569 |
VU590
ROMK inhibitor
|
VU590 is the first small-molecule inhibitor of renal outer medullary potassium channel (ROMK, Kir1.1) and Kir7.1 with IC50 of 294 nM for ROMK. |
| PC-60559 |
RX 871024
|
RX 871024 is an imidazoline compound that stimulate insulin release by inhibition of ATP-dependent K+ channels and inducing of Ca2+ mobilization in mouse pancreatic beta-cells. |
| PC-70220 |
Paxilline
BKCa inhibitor
|
Paxilline is a potent blocker of high-conductance Ca2+-activated K+ (BKCa, KCa1.1) channels that binds to the α-subunit of BKCa with Ki of 1.9 nM. |
| PC-60460 |
MK-7145
ROMK inhibitor
|
MK-7145 is a potent, selective, and oral renal outer medullary potassium channel (ROMK, Kir1.1) inhibitor with IC50 of 68 nM. |
| PC-60338 |
BL-1249
TREK-1 activator
|
BL-1249 (BL1249) is a potent K2P2.1 (TREK-1) channel activator, enhance the activity of TREK1 currents and produces relaxation of 30 mM KCl-induced contractions in rat bladder strips with EC50 of 1.12 uM. |
| PC-60337 |
ML335
TREK-1/2 activator
|
ML335 (ML 335) is anovel potent, selective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) channels activator with EC50 of 14.3 and 5.2 uM, respectively. |
| PC-60336 |
ML402
TREK channel inhibitor
|
ML402 (ML-402) is a potent, selective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) channels activator with EC50 of 13.7 and 5.9 uM, respectively. |
