Phosphodiesterase (PDE) (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-21899	Anagrelide hydrochloride PDE3 inhibitor	Anagrelide hydrochloride (BL4162A) is a potent inhibitor of phosphodiesterase type III (PDE3) with IC50 of 36 nM, inhibits platelet aggregation and bone marrow megakaryocytopoiesis.
PC-21518	D159687 PDE4D inhibitor	D159687 is a selective, negative allosteric modulator (inhibitor) of PDE4D with IC50 of 1.9 nM, >1,000 time more selective against PDE4 compared with other PDEs.
PC-20981	PDE12 inhibitor Compound 1 PDE12 inhibitor	PDE12 inhibitor Compound 1 is a potent, selective inhibitor of phosphodiesterase 12 (PDE12) with pIC50 of 9.1 and Ki of 17.5 nM, >1000-fold selectivity over EEP nuclease family member CNOT6.
PC-20974	CC-11050 PDE4 inhibitor	Dovramilast (CC-11050) is a potent and orally active phosphodiesterase 4 (PDE4) inhibitor, CC-11050 is a promising candidate for host directed therapy of patients with pulmonary TB.
PC-45081	(R)-(-)-Rolipram	A more active enantiomer of the PDE4 inhibitor rolipram.

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