| Cat. No. |
Product Name |
Information |
| PC-45821 |
PF-2545920
PDE10A inhibitor
|
PF-2545920 (Mardepodect, MP-10) is a potent and selective PDE10A inhibitor with IC50 of 0.37 nM. |
| PC-45440 |
Avanafil
PDE5 inhibitor
|
Avanafil (TA1790) is a potent and highly selective PDE5 inhibitor (IC50=5.2 nM) for erectile dysfunction. |
| PC-42235 |
SCH00013
Cardiotonic agent
|
SCH00013 is a cardiotonic agent that acts as a calcium sensitizer with no chronotropic activity in mammalian cardiac muscle, elicits positive inotropic effect in dog and rabbit ventricular muscles (EC50=9.2 uM). |
| PC-45081 |
(R)-(-)-Rolipram
PDE4 inhibitor
|
(R)-(-)-Rolipram ((R)-Rolipram) is a more active enantiomer of the PDE4 inhibitor rolipram, shows 2-10-fold more potent than the S-(+) enantiomer rolipram. |
| PC-28608 |
PDE1-IN-4
PDE1C inhibitor
|
PDE1-IN-4 (compound 2g) is a potent and selective phosphodiesterase-1 (PDE1) inhibitor with IC50 of 10 nM, 145 nM, and 354 nM for PDE1C, PDE1A, and PDE1B respectively. |
| PC-28442 |
Sulfoaildenafil
PDE5 inhibitor
|
Sulfoaildenafil (Thioaildenafil) is an analog of sildenafil, potent and highly selective inhibitor of phosphodiesterase 5 (PDE5). |
| PC-28441 |
Aildenafil
PDE5 inhibitor
|
Aildenafil (Methisosildenafil, Dimethyl sildenafil) is a potent and highly selective inhibitor of phosphodiesterase 5 (PDE5) for the treatment of erectile dysfunction (ED). |
| PC-28251 |
OPC-33540
PDE3 inhibitor
|
OPC-33540 (OPC33540) is a potent, highly selective and competitive PDE3 inhibitor with IC50 of 0.32 nM and 1.5 nM for PDE3A and PDE3AB respectively. |
| PC-28060 |
PDE7-IN-3
PDE7 inhibitor
|
PDE7-IN-3 is a highly potent phosphodiesterase 7 (PDE7) with Ki of 1.9 nM (PDE7A), shows potential for treating neuropathic pain. |
| PC-28059 |
PDE7-IN-2
PDE7 inhibitor
|
PDE7-IN-2 is a potent phosphodiesterase 7 (PDE7) with IC50 of 2.1 uM. |
| PC-27465 |
Giclanfentrine
PDE3/4 inhibitor
|
Giclanfentrine (TQC3721) is a potent, selective phosphodiesterase PDE3/PDE4 dual inhibitor. |
| PC-27424 |
Envogmilast
PDE4 inhibitor
|
Envogmilast is a potent, selective PDE4 inhibitor. |
