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Request The Product List ofPhosphodiesterase (PDE) Phosphodiesterase (PDE)

Cat. No. Product Name Information
PC-63096

CDP-840

PDE4 inhibitor

CDP-840 (CDP840;L-765527) is a potent and selective PDE4 inhibitor with IC50 of 4-45 nM for PDE4 extracted from tissues or recombinant PDE 4 isoforms expressed in yeast.
PC-63095

ONO-6126

PDE4 inhibitor

ONO-6126 is a potent and selective PDE4 inhibitor for the treatment of bronchial asthma and allergic conjunctivitis..
PC-63094

Oglemilast

PDE4 inhibitor

Oglemilast (GRC-3886) is a potent and selective PDE4 inhibitor with IC50 of 2.5 and 1.7 nM for PDE4B and PDE4D, respectively..
PC-63093

Tetomilast

PDE4 inhibitor

Tetomilast (OPC-6535) is a superoxide anion production inhibitor that inhibits PDE4 and proinflammatory functions of leukocytes including superoxide production and cytokine release.
PC-63092

Filaminast

PDE4 inhibitor

Filaminast (WAY-PDA-641, PDA-641, WAY-123641) is a potent and selective PDE4 inhibitor with IC50 of 420 nM, displays 36-fold selectivity over PDE3.
PC-63091

Lirimilast

PDE4 inhibitor

Lirimilast (BAY19-8004, BAY 198004) is a potent and selective PDE4 inhibitor with IC50 of 49 nM, shows potential for the treatment of COPD.
PC-63090

Tofimilast

PDE4 inhibitor

Tofimilast (CP-325366) is a potent, selective PDE4 inhibitor with IC50 of 23, 13 and 13 nM for PDE4A, PDE4B, and PDE4D, respectively.
PC-63089

Piclamilast

PDE4 inhibitor

Piclamilast (RP-73401) is a potent and highly selective PDE4 inhibitor with IC50 of 1.2 nM.
PC-63088

HT-0712

PDE4 inhibitor

HT-0712 (IPL-455903) is a novel potent, selective PDE4 inhibitor with IC50 of 0.15 uM for PDE4D3, without effect on PDE1B, PDE3A, and PDE10A.
PC-63029

TPN729 maleate

PDE5 inhibitor

TPN729 maleate is a novel potent, selective phosphodiesterase type 5 (PDE5) inhibitor with IC50 of 2.28 nM.
PC-63028

TPN729

PDE5 inhibitor

TPN729 is a novel potent, selective phosphodiesterase type 5 (PDE5) inhibitor with IC50 of 2.28 nM, shows better selectivity profile 2.5 times higher than sildenafil against PDE6 and 500 times higher than tadalafil against PDE11.
PC-62973

FCPR03

PDE4 inhibitor

FCPR03 is a novel potent, selective PDE4 inhibitor with IC50 of 60, 31 and 47 nM for PDE4CAT (PDE4 catalytic domain), PDE4B1 and PDE4D7, respectively.

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